Browsing Faculty of Medicine by Title

Now showing items 4866-4885 of 8839

    • Lactate is associated with mortality in very old intensive care patients suffering from COVID-19: results from an international observational study of 2860 patients 

      Bruno, Raphael Romano; Wernley, Bernhard; Flaatten, Hans; Fjølner, Jesper; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Binnebössel, Stephan; Baldia, Philipp Heinrich; Kelm, Malte; Beil, Michael; Sigal, Sivri; van Heerden, Peter Vernon; Szczeklik, Wojciech; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Wollborn, Jakob; Banzo, Maria José Arche; Fuest, Kristina; Marsh, Brian; Andersen, Finn H.; Moreno, Rui; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand; Jung, Christian (Journal article; Peer reviewed, 2021)
      Purpose: Lactate is an established prognosticator in critical care. However, there still is insufficient evidence about its role in predicting outcome in COVID-19. This is of particular concern in older patients who have ...

    • The laminin response in inflammatory bowel disease: Protection or malignancy? 

      Spenle, Caroline; Lefebvre, Olivier; Lacroute, Joel; Mechine-Neuville, Agnes; Barreau, Frederick; Blottiere, Herve M; Duclos, Bernard; Arnold, Christiane; Hussenet, Thomas; Hemmerle, Joseph; Gullberg, Donald; Kedinger, Michele; Sorokin, Lydia; Orend, Gertraud; Simon-Assmann, Patricia (Peer reviewed; Journal article, 2014-10-27)
      Laminins (LM), basement membrane molecules and mediators of epithelial-stromal communication, are crucial in tissue homeostasis. Inflammatory Bowel Diseases (IBD) are multifactorial pathologies where the microenvironment ...

    • Langtidsoppfølging av pasienter med Oral Lichen Planus - en retrospektiv studie 

      Strann, Linn Oppedal; Klyve, Rachel Fleten (Master thesis, 2010-02-01)
      The aim of this study was to evaluate progression of clinical appearance and symptoms in patients diagnosed with oral lichen planus (OLP), and observe if any malign transformation occurred. The study was retrospective and ...

    • Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in utero – the Norwegian Mother and Child Cohort Study 

      Husebye, Elisabeth Synnøve Nilsen; Gilhus, Nils Erik; Spigset, Olav; Daltveit, Anne Kjersti; Bjørk, Marte-Helene (Peer reviewed; Journal article, 2020)
      Background and purpose: The purpose was to examine the consequences of antiepileptic drug (AED) exposure during pregnancy on language abilities in children aged 5 and 8 years of mothers with epilepsy. Methods: The study ...

    • Laparoscopic rectal cancer resection yields comparable clinical and oncological results with shorter hospital stay compared to open access: a 5-year national cohort 

      Myrseth, Elisabeth; Gjessing, Petter Fosse; Nymo, Linn Såve; Kørner, Hartwig; Kvaløy, Jan Terje; Norderval, Stig (Journal article; Peer reviewed, 2023)
      Purpose Although widely applied, the results following laparoscopic rectal resection (LRR) compared to open rectal resection (ORR) are still debated. The aim of this study was to assess clinical short- and long-term ...

    • Laparoskopisk gastrisk bypassoperasjon versus livsstilsbehandling av unge med sykelig overvekt 

      Hjelmesæth, Jøran; Hertel, Jens Kristoffer; Holt, Ane Hjetland; Benestad, Beate; Seeberg, Lars Thomas; Lindberg, Morten; Halvorsen, Erling; Juliusson, Petur Benedikt; Sandbu, Rune; Lekhal, Samira (Journal article; Peer reviewed, 2020)
      BAKGRUNN Kunnskapsgrunnlaget om effekten av og komplikasjoner ved vektreduserende kirurgi hos ungdom er mangelfullt. Hovedformålet med 4XL-studien er å avklare om laparoskopisk Roux-en-Y gastrisk bypassoperasjon (LGBP) ...

    • A large community outbreak of waterborne giardiasis- delayed detection in a non-endemic urban area 

      Nygård, Karin; Schimmer, Barbara; Søbstad, Øystein; Walde, Anna; Tveit, Ingvar; Langeland, Nina; Hausken, Trygve; Aavitsland, Preben (BMC Public Health 6(141), Peer reviewed; Journal article, 2006-05-25)
      Background: Giardia is not endemic in Norway, and more than 90% of reported cases acquire the infection abroad. In late October 2004, an increase in laboratory confirmed cases of giardiasis was reported in the city of ...

    • Large-scale external validation and comparison of prognostic models: An application to chronic obstructive pulmonary disease 

      Guerra, Beniamino; Haile, Sarah R.; Lamprecht, Bernd; Ramírez, Ana S.; Martinez-Camblor, Pablo; Kaiser, Bernhard; Alfageme, Inmaculada; Almagro, Pere; Casanova, Ciro; Esteban-González, Cristóbal; Soler-Cataluña, Juan J.; de-Torres, Juan P.; Miravitlles, Marc; Celli, Bartolomé R.; Marin, Jose M.; ter Riet, Gerben; Sobradillo, Patricia; Lange, Peter; Garcia-Aymerich, Judith; Antó, Jósep Maria; Turner, Alice M.; Han, Meilan K.; Langhammer, Arnulf; Leivseth, Linda; Bakke, Per S.; Johannessen, Ane; Oga, Toru; Cosio, Borja; Ancochea-Bermúdez, Julio; Echazarreta, Andrés; Roche, Nicolas; Burgel, Pierre-Régis; Sin, Don D.; Soriano, Joan B.; Puhan, Milo A. (Peer reviewed; Journal article, 2018-03-02)
      Background: External validations and comparisons of prognostic models or scores are a prerequisite for their use in routine clinical care but are lacking in most medical fields including chronic obstructive pulmonary disease ...

    • Large-scale genomics unveil polygenic architecture of human cortical surface area 

      Chen, Chi-Hua; Peng, Qian; Schork, Andrew J.; Lo, Min-Tzu; Fan, Chun-Chieh; Wang, Yunpeng; Desikan, Rahul S.; Bettella, Franscesco; Hagler, Donald J.; Westlye, Lars Tjelta; Kremen, William S.; Jernigan, Terry L.; Le Hellard, Stephanie; Steen, Vidar Martin; Espeseth, Thomas; Huentelman, Matt; Håberg, Asta; Agartz, Ingrid; Djurovic, Srdjan; Andreassen, Ole Andreas; Schork, Nicholas; Dale, Anders (Peer reviewed; Journal article, 2015-07-20)
      Little is known about how genetic variation contributes to neuroanatomical variability, and whether particular genomic regions comprising genes or evolutionarily conserved elements are enriched for effects that influence ...

    • Large-scale resting state network correlates of cognitive impairment in Parkinson’s disease and related dopaminergic deficits 

      Lebedev, Alexander; Westman, Eric; Simmons, Andrew; Lebedeva, Aleksandra; Siepel, Françoise J.; Pereira, Joana B.; Aarsland, Dag (Peer reviewed; Journal article, 2014-04-03)
      Cognitive impairment is a common non-motor feature of Parkinson’s disease (PD). Understanding the neural mechanisms of this deficit is crucial for the development of efficient methods for treatment monitoring and augmentation ...

    • Laryngeal response patterns during mechanically assisted cough in Amyotrophic Lateral Sclerosis 

      Andersen, Tiina Maarit (Doctoral thesis, 2018-06-21)
      Background: Patients with amyotrophic lateral sclerosis (ALS) are treated with mechanical cough assist devices using the technique of mechanical insufflationexsufflation (MI-E) in order to improve cough and enhance clearance ...

    • Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis 

      Andersen, Tiina Maarit; Sandnes, Astrid; Brekka, Anne Kristine; Hilland, Magnus; Clemm, Hege; Fondenes, Ove; Tysnes, Ole Bjørn; Heimdal, John-Helge; Halvorsen, Thomas; Vollsæter, Maria; Røksund, Ola Drange (Peer reviewed; Journal article, 2017)
      Background: Most patients with amyotrophic lateral sclerosis (ALS) are treated with mechanical insufflation–exsufflation (MI-E) in order to improve cough. This method often fails in ALS with bulbar involvement, allegedly ...

    • Laryngeal tube use in out-of-hospital cardiac arrest by paramedics in Norway 

      Sunde, Geir Arne; Brattebø, Guttorm; Ødegården, Terje; Kjernlie, Dag Frode; Rødne, Emma Sjøgren; Heltne, Jon-Kenneth (Peer reviewed; Journal article, 2012-12-18)
      Background: Although there are numerous supraglottic airway alternatives to endotracheal intubation, it remains unclear which airway technique is optimal for use in prehospital cardiac arrests. We evaluated the use of the ...

    • Larynx during exercise: the unexplored bottleneck of the airways 

      Røksund, Ola Drange; Heimdal, John-Helge; Olofsson, Jan; Maat, Robert; Halvorsen, Thomas (Peer reviewed; Journal article, 2014-07-18)
      Exercise-induced shortness of breath is not uncommon in otherwise healthy young people. Based on the presenting symptoms alone, it is challenging to distinguish exercise-induced asthma (EIA) from exercise-induced obstruction ...

    • Larynx in exercising humans. The unexplored bottleneck of the airways 

      Røksund, Ola Drange (Doctoral thesis, 2012-06-21)

    • Laserbehandling av infeksjoner ved dentale implantater 

      Alstad, Miriam Elisabeth; Angelsen, Stine Victoria (Master thesis, 2009-04-27)
      En gjennomgang av litteraturen indikerer at peri- implantatrelaterte sykdommer oppstår svært ofte etter implantatforankret protetikk. Det er derfor viktig at det utarbeides forslag til behandlingsprotokoller og utprøves ...

    • Laserbehandling av infiserte tannkjøttslommer 

      Espervik, Annika; Eriksen, Elisabeth Schilbred (Master thesis, 2009-04-27)
      De fleste pasienter med kronisk marginal periodontitt responderer godt på tradisjonell periodontal behandling, men ca. 10 % ser ut til å ha en bakterieflora som er særlig behandlingsresistent. For disse pasientene er ...

    • Late Onset Myasthenia Gravis Is Associated with HLA DRB1*15:01 in the Norwegian Population 

      Maniaol, Angelina H.; Elsais, Ahmed; Lorentzen, Åslaug R.; Owe, Jone F.; Viken, Marte K.; Gilhus, Nils Erik (Peer reviewed; Journal article, 2012-05-09)
      Background: Acquired myasthenia gravis (MG) is a rare antibody-mediated autoimmune disease caused by impaired neuromuscular transmission, leading to abnormal muscle fatigability. The aetiology is complex, including genetic ...

    • Late-onset sepsis in very preterm infants in Norway in 2009-2018: A population-based study 

      Huncikova, Zuzana; Vatne, Anlaug; Stensvold, Hans Jørgen; Lang, Astri Maria; Støen, Ragnhild; Brigtsen, Anne Karin; Salvesen, Bodil; Øymar, Knut Asbjørn Alexander; Rønnestad, Arild Erland; Klingenberg, Claus Andreas (Journal article; Peer reviewed, 2023)
      Objective: To evaluate epidemiology and outcomes among very preterm infants (<32 weeks’ gestation) with culture-positive and culture-negative late-onset sepsis (LOS). Design: Cohort study using a nationwide, population-based ...

    • Late-Stage Prostate Cancer and Prostate Cancer Mortality : A Population-Based Study 

      Löffeler, Sven (Doctoral thesis, 2019-11-29)
      AIMS OF THE THESIS The aim of this thesis was to provide a better understanding of the final stages of PCa, metastatic castration resistant PCa and PCa death. We further aimed to address the consequences of possible ...