Blar i Faculty of Medicine på tittel
Viser treff 8289-8308 av 8754
-
Tumor budding score predicts lymph node status in oral tongue squamous cell carcinoma and should be included in the pathology report
(Journal article; Peer reviewed, 2020)Background The majority of oral cavity cancers arise in the oral tongue. The aim of this study was to evaluate the prognostic value of tumor budding in oral tongue squamous cell carcinoma, both as a separate variable and ... -
Tumor HPV status, level of regulatory T cells and macrophage infiltration predict up to 20-year non-disease-specific survival in oropharynx squamous cell carcinoma patients
(Journal article; Peer reviewed, 2022)Oropharynx squamous cell carcinoma (OPSCC) is of special interest because human papilloma virus (HPV) and/or smoking cause this disease. Influxes of inflammatory cells into such tumors are known to vary with prognoses. ... -
Tumor infiltration levels of CD3, Foxp3 (+) lymphocytes and CD68 macrophages at diagnosis predict 5-year disease-specific survival in patients with oropharynx squamous cell carcinoma
(Journal article; Peer reviewed, 2022)Head and neck cancer (HNC) is the sixth most common cancer worldwide. Oropharyngeal (OP) cancers are of special interest because of possible underlying HPV infection which is tied to prognosis. Influxes of inflammatory ... -
Tumor interstitial fluid formation, characterization, and clinical implications
(Peer reviewed; Journal article, 2015-05-26)The interstitium, situated between the blood and lymph vessels and the cells, consists of a solid or matrix phase and a fluid phase representing the tissue microenvironment. In the present review, we focus on the interstitial ... -
Tumor necrosis is associated with increased alphav beta3 integrin expression and poor prognosis in nodular cutaneous melanomas
(Peer reviewed; Journal article, 2008-12-05)Background: Tumor necrosis and apoptotic activity are considered important in cancer progression, but these features have not been much studied in melanomas. Our hypothesis was that rapid growth in cutaneous melanomas of ... -
Tumor oxygenation - influence on mammary tumor growth, progression and response to chemotherapy
(Doctoral thesis, 2011-04-28) -
Tumor-associated lymphocytes and macrophages are related to stromal elastosis and vascular invasion in breast cancer
(Journal article; Peer reviewed, 2021)The tumor microenvironment plays a critical role in breast cancer progression. Here, we investigated tumor-infiltrating lymphocytes (TILs) and associations with macrophage numbers, tumor stromal elastosis, vascular invasion, ... -
Tumor-associated macrophages in gliomas—basic insights and treatment opportunities
(Journal article; Peer reviewed, 2022)Glioma refers to a group of primary brain tumors which includes glioblastoma (GBM), astrocytoma and oligodendroglioma as major entities. Among these, GBM is the most frequent and most malignant one. The highly infiltrative ... -
Tumor-Derived Lactic Acid Contributes to the Paucity of Intratumoral ILC2s
(Journal article; Peer reviewed, 2020)Group 2 innate lymphoid cells (ILC2s) are abundant in non-lymphoid tissues and increase following infectious and inflammatory insults. In solid tumors, however, ILC2s constitute a relatively small proportion of immune ... -
Tumor-penetrating peptide for systemic targeting of Tenascin-C
(Journal article; Peer reviewed, 2020)Extracellular matrix in solid tumors has emerged as a specific, stable, and abundant target for affinity-guided delivery of anticancer drugs. Here we describe the homing peptide that interacts with the C-isoform of Tenascin-C ... -
Tumour texture features from preoperative CT predict high-risk disease in endometrial cancer
(Journal article; Peer reviewed, 2021-01)Background: To enable more individualised treatment of endometrial cancer, improved methods for preoperative tumour characterization are warranted. Texture analysis is a method for quantification of heterogeneity in images, ... -
Tumour-associated glial host cells display a stem-like phenotype with a distinct gene expression profile and promote growth of GBM xenografts
(Peer reviewed; Journal article, 2017-02-07)Background: Little is known about the role of glial host cells in brain tumours. However, supporting stromal cells have been shown to foster tumour growth in other cancers. Methods: We isolated stromal cells from patient-derived ... -
Tunneling nanotubes: Diversity in morphology and structure
(Peer reviewed; Journal article, 2014-02-06)Tunneling nanotubes (TNTs) are recently discovered thin membranous tubes that interconnect cells. During the last decade, research has shown TNTs to be diverse in morphology and composition, varying between and within cell ... -
Turnover of IPS employment specialists: Rates and predictors
(Journal article; Peer reviewed, 2022)Background: There are anecdotal reports of high job turnover of Individual Placement and Support employment specialists. However, no studies have addressed this issue. Objective: To explore whether turnover rates among ... -
Turnusordningar i helsevesenet - Erfaringar med kort kviletid mellom vakter hjå helsepersonell i todelt turnus: Ein fokusgruppeintervjustudie
(Master thesis, 2023-05-15)SAMANDRAG Bakgrunn: Helsepersonell i todelt turnus må ofte belage seg på å arbeide vaktkombinasjonen sein-tidleg, som gir kortare enn 11 timar kviletid mellom to vakter, «quick return». Quick return er relatert til fleire ... -
Tweeting the meeting: Quantitative and qualitative twitter activity during the 38th ESSO conference
(Peer reviewed; Journal article, 2019-02)Introduction: Social media is increasingly used to share information with the potential for fast and wide reach. Data on use during surgical oncology conferences is limited. We aimed to monitor twitter usage during a ... -
Twin Pregnancies: Long-term Maternal Mortality, Birthweight in Subsequent Pregnancy and Adverse Pregnancy Outcomes in Next Generation
(Doctoral thesis, 2024-04-15)Bakgrunn: Tvillingsvangerskap har vært mindre studert enn svangerskap med enkeltfødte. Ved å bruke populasjonsbaserte registerdata ønsket vi å belyse sammenheng mellom tvillingsvangerskap, reproduksjon og langtidsdødelig ... -
Two age peaks in the incidence of chronic fatigue syndrome/myalgic encephalomyelitis: a population-based registry study from Norway 2008-2012
(Peer reviewed; Journal article, 2014-10-01)Background: The aim of the current study was to estimate sex- and age-specific incidence rates of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) using population-based registry data. CFS/ME is a debilitating ... -
Two interventions to treat pain disorders and post-traumatic symptoms among Syrian refugees: protocol for a randomized controlled trial
(Peer reviewed; Journal article, 2019)Background: There is a high prevalence of pain and post-traumatic symptoms among refugees and feasible interventions to manage these are needed. However, knowledge about the effect of physiotherapy and psychological group ... -
Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases
(Journal article; Peer reviewed, 2022)Context Maturity onset diabetes of the young, type 8 (MODY8) is associated with mutations in the CEL gene, which encodes the digestive enzyme carboxyl ester lipase. Several diabetes cases and families have in recent years ...