Browsing Faculty of Medicine by Title
Now showing items 8345-8364 of 8839
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Tribal differences in perception of tuberculosis : a possible role in tuberculosis control in Arusha, Tanzania
(Peer reviewed; Journal article, 2003-10)SETTING: Arusha, Tanzania. OBJECTIVE: To determine tribal differences in knowledge and practices that might influence tuberculosis control. METHOD: Twenty-seven villages were selected randomly out of 242 villages in four ... -
Tricalcium silicate cements: in-vitro comparative studies of mechanical and biological characteristics of relevance to regenerative endodontics
(Doctoral thesis, 2020-12-08)Tricalcium silicate cements (TSC), are bioactive ceramic materials with a wide range of clinical applications in the field of “regenerative endodontics”, i.e. tissue engineering concepts applied to regeneration of damaged ... -
Trifluoperazine prolongs the survival of experimental brain metastases by STAT3-dependent lysosome membrane permeabilization
(Journal article; Peer reviewed, 2020)Brain metastasis is a major cause of mortality in melanoma patients. The blood-brain barrier (BBB) prevents most anti-tumor compounds from entering the brain, which significantly limits their use in the treatment of brain ... -
Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination
(Peer reviewed; Journal article, 2017-09-05)Background: Resistance to adjuvant radiotherapy is a major cause of treatment failure in patients with glioblastoma (GBM). Autophagy inhibitors have been shown to enhance the efficacy of radiotherapy for certain solid ... -
TRIGEN INTERTAN Intramedullary Nail Versus Sliding Hip Screw
(Peer reviewed; Journal article, 2013-02-06)Background: Both intramedullary nails and sliding hip screws are used with good results in the treatment of intertrochanteric and subtrochanteric fractures. The aim of our study was to assess whether use of the TRIGEN ... -
The triglyceride-glucose index as a measure of insulin resistance and risk of obesity-related cancers
(Peer reviewed; Journal article, 2020)Background: The role of insulin resistance as a mediator in the association of body mass index (BMI) with site-specific cancer risk has, to our knowledge, never been systematically quantified. Methods: Altogether 510 471 ... -
TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα
(Journal article; Peer reviewed, 2021)NF-κB signaling plays a critical role in tumor growth and treatment resistance in GBM as in many other cancers. However, the molecular mechanisms underlying high, constitutive NF-κB activity in GBM remains to be elucidated. ... -
TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein
(Journal article; Peer reviewed, 2022)Background The tripartite motif (TRIM) family of proteins plays a key role in the developmental growth and therapeutic resistance of many tumors. However, the regulatory mechanisms and biological functions of TRIM proteins ... -
Trimethyllysine predicts all-cause and cardiovascular mortality in community-dwelling adults and patients with coronary heart disease
(Journal article; Peer reviewed, 2021)Aims Trimethyllysine (TML) is involved in carnitine synthesis, serves as a precursor of trimethylamine N-oxide (TMAO) and is associated with cardiovascular events in patients with established coronary heart disease (CHD). ... -
Trochanteric stabilizing plate in the treatment of trochanteric fractures: a scoping review
(Journal article; Peer reviewed, 2021)Background and purpose — The trochanteric stabilizing plate (TSP) may be used as an adjunct to a sliding hip screw (SHS) in the treatment of trochanteric fractures to increase construct stability. We performed a scoping ... -
Truncating and zinc-finger variants in GLI2 are associated with hypopituitarism
(Journal article; Peer reviewed, 2022)Variants in transcription factor GLI2 have been associated with hypopituitarism and structural brain abnormalities, occasionally including holoprosencephaly (HPE). Substantial phenotypic variability and nonpenetrance have ... -
Trunk Control and Lesion Locations According to Alberta Stroke Program Early CT Score in Acute Stroke: A Cross-Sectional Study
(Peer reviewed; Journal article, 2014-02-14)Background: Stroke is a leading cause of disability in elderly people. Lesion location and size, and trunk control early after stroke have been found predictive of functional outcome. Trunk control is an important aspect ... -
Trunk control in stroke. Aspects of measurement, relation to brain lesion, and change after rehabilitation
(Doctoral thesis, 2014-09-19)Stroke is a leading cause of disability worldwide and affects mostly elderly people. Neurorehabilitation is important for reducing the long-term consequences of stroke, aiming to achieve an optimal functional recovery for ... -
The Trunk Impairment Scale - modified to ordinal scales in the Norwegian version
(Peer reviewed; Journal article, 2012-08)Purpose: To translate the Trunk Impairment Scale (TIS), a measure of trunk control in patients with stroke, into Norwegian (TIS-NV), and to explore its construct validity, internal consistency, intertester and test-retest ... -
Trust-building interventions to home-dwelling persons with dementia who resist care
(Journal article; Peer reviewed, 2022)Background: Providing care for a home-dwelling person with dementia who resists care is an ethical and practical complex and challenging task. Faced with a growing number of persons with dementia, the healthcare professional’s ... -
Trustingly bewildered. How first-year medical students make sense of their learning experience in a traditional, preclinical curriculum
(Peer reviewed; Journal article, 2018)Background: Traditional preclinical curricula based on memorization of scientific facts constitute learning environments which may negatively influence both factual understanding and professional identity development in ... -
The Truth behind the Zeros: A New Approach to Principal Component Analysis of the Neuropsychiatric Inventory
(Journal article; Peer reviewed, 2021)Psychiatric syndromes in dementia are often derived from the Neuropsychiatric Inventory (NPI) using principal component analysis (PCA). The validity of this statistical approach can be questioned, since the excessive ... -
Tryggere når det trengs
(Master thesis, 2020-08-29)Avdelingsledere har ansvar for at medarbeidere innehar nødvendig kunnskap for å utføre oppgavene som er tiltenkt stillingene deres. Dette er pålagt gjennom lover og forskrifter. Studien fokuserer på leders ansvar for ... -
Tryptophan and kynurenine pathway metabolites in neuropsychiatric disorders
(Doctoral thesis, 2024-05-21)Bakgrunn: Kynureninar er ei gruppe metabolittar av den kosthaldsavhengige aminosyra tryptofan (Trp) som er involverte i ei rekkje biologiske mekanismar, mellom anna inflammasjon og reguleringa av nevrotransmitteren glutamat. ... -
Tryptophan catabolites as metabolic markers of vitamin B-6 status evaluated in cohorts of healthy adults and cardiovascular patients
(Journal article; Peer reviewed, 2020)Background Vitamin B-6 status is routinely measured as pyridoxal 5′-phosphate (PLP) in plasma. Low concentrations of PLP are associated with rheumatic, cardiovascular, and neoplastic diseases. We have previously shown ...