Blar i Faculty of Medicine på tittel

Viser treff 8445-8464 av 8833

    • Unmet Surgical Need in Malawi 

      Varela, Carlos Gomes (Doctoral thesis, 2021-10-04)
      Introduction Globally, and especially in sub-Saharan Africa, including Malawi, surgical conditions receive a low level of priority in national health systems. The burden of surgical diseases is not well documented and the ...

    • Unperturbed cytotoxic lymphocyte phenotype and function in myalgic encephalomyelitis/chronic fatigue syndrome patients 

      Theorell, Jakob; Bileviciute-Ljungar, Indre; Tesi, Bianca; Schlums, Heinrich; Johnsgaard, Mette Sophie; Asadi-Azarbaijani, Babak; Strand, Elin Bolle; Bryceson, Yenan (Peer reviewed; Journal article, 2017-06-26)
      Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a debilitating disorder linked to diverse intracellular infections as well as physiological stress. Cytotoxic lymphocytes combat intracellular infections. ...

    • Unravelling the prospective associations between mixed anxiety-depression and insomnia during the course of cognitive behavioral therapy 

      Thun, Eirunn; Sivertsen, Børge; Knapstad, Marit; Smith, Otto Robert Frans (Journal article; Peer reviewed, 2019)
      Objective Previous studies have suggested that there is a reciprocal relationship between anxiety/depression and insomnia. However, little is known about the prospective relationships between these constructs across the ...

    • Unsubstantiated belief in the diagnostic accuracy of the triad of abusive head trauma may lead to incorrect diagnoses of alleged abuse cases 

      Wester, Knut; Wikström, Johan; Lynøe, Niels; Eriksson, Anders (Journal article; Peer reviewed, 2021)

    • Unsupervised clustering of missense variants in HNF1A using multidimensional functional data aids clinical interpretation 

      Althari, Sara; Najmi, Laeya Abdoli; Bennett, Amanda J.; Aukrust, Ingvild; Rundle, Jana K.; Colclough, Kevin; Molnes, Janne; Kaci, Alba; Nawaz, Sameena; van der Lugt, Timme; Hassanali, Neelam; Mahajan, Anubha; Molven, Anders; Ellard, Sian; McCarthy, Mark I.; Bjørkhaug, Lise; Njølstad, Pål Rasmus; Gloyn, Anna L. (Journal article; Peer reviewed, 2020-10-01)
      Exome sequencing in diabetes presents a diagnostic challenge because depending on frequency, functional impact, and genomic and environmental contexts, HNF1A variants can cause maturity-onset diabetes of the young (MODY), ...

    • Unveiling sex bias and adverse neonatal outcomes in ultrasound estimation of gestational age: A population-based cohort study 

      Einum, Anders; Sørbye, Linn Marie; Nilsen, Roy Miodini; Ebbing, Cathrine; Morken, Nils-Halvdan (Journal article; Peer reviewed, 2024)
      Background Gestational age estimation by second-trimester ultrasound biometry introduces systematic errors due to sex differences in early foetal growth, consequently increasing the risk of adverse neonatal outcomes. ...

    • Update on primary sclerosing cholangitis 

      Karlsen, Tom Hemming; Boberg, Kirsten Muri (Peer reviewed; Journal article, 2013-09)
      Primary sclerosing cholangitis (PSC) remains one of the most challenging conditions of clinical hepatology. There has been a steady growth in research to overcome this fact and the present review aims at summarizing the ...

    • An Update on Vitamin D and Disease Activity in Multiple Sclerosis 

      Smolders, Joost; Torkildsen, Øivind; Camu, William; Holmøy, Trygve (Peer reviewed; Journal article, 2019)
      Vitamin D and its main active metabolite 1,25-dihydroxyvitamin D serve a crucial role in maintenance of a healthy calcium metabolism, yet have additional roles in immune and central nervous system cell homeostasis. Serum ...

    • Updated total IgE reference intervals in Norwegian adults 

      Vinnes, Erik Wilhelm; Skarbø, Birthe Rochlenge Skarbø; Wentzel-Larsen, Tore; Sylte, Marit Sverresdotter; Apelseth, Torunn Oveland (Journal article; Peer reviewed, 2023)
      Background It is important and expected of laboratories to provide updated reference intervals to the clinician. As no recent publications report adult total IgE reference intervals on a Scandinavian population, the aim ...

    • Upgrades from Previous Cardiac Implantable Electronic Devices Compared to De Novo Cardiac Resynchronization Therapy Implantations: Results from CRT Survey-II in the Turkish Population 

      Koçyiğit, Duygu; Sarıgül, Nedim Umutay; Altın, Timuçin; Çay, Serkan; Normand, Camilla Jacqueline Hansine; Linde, Cecilia; Dickstein, Kenneth (Journal article; Peer reviewed, 2022)
      Objective: Cardiac resynchronization therapy is the guideline-directed treatment option in selected heart failure with reduced left ventricular ejection fraction patients. Data regarding the contemporary clinical practice ...

    • Upper limb disability in Norwegian workers with hand-arm vibration syndrome 

      Buhaug, Kristin; Moen, Bente E.; Irgens, Ågot (Peer reviewed; Journal article, 2014-02-11)
      Background: Hand-arm vibration syndrome (HAVS) is a well-known disease among workers using hand-held vibrating tools. These patients experience major symptoms from their upper limbs. However, there are few studies on ...

    • Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis 

      Martínez-Nieto, Guillermo A.; Teppo, Hanna-Riikka; Petrelius, Noora; Izzi, Valerio; Devarajan, Raman; Petäistö, Tiina; Liu, Hengshuo; Kim, Kris S.; Karppinen, Sanna-Maria; Ruotsalainen, Heli; Koivunen, Jarkko; Mäki, Joni M.; Walker, Gilbert C.; Pihlajaniemi, Taina; Gullberg, Elon Donald; Heljasvaara, Ritva Leena (Journal article; Peer reviewed, 2022)
      Integrin α11β1 is a collagen-binding integrin that is needed to induce and maintain the myofibroblast phenotype in fibrotic tissues and during wound healing. The expression of the α11 is upregulated in cancer-associated ...

    • Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation 

      Pettersen, Ina Katrine Nitschke; Tusubira, Deusdedit; Ashrafi, Hanan; Dyrstad, Sissel Elisabeth; Hansen, Lena; Liu, Xiao-Zheng; Hodneland, Linn I.; Løvsletten, Nils Gunnar; Berge, Kjetil; Wergedahl, Hege; Bjørndal, Bodil; Fluge, Øystein; Bruland, Ove; Rustan, Arild; Halberg, Nils; Røsland, Gro Vatne; Berge, Rolf Kristian; Tronstad, Karl Johan (Peer reviewed; Journal article, 2019)
      Fatty acid oxidation is a central fueling pathway for mitochondrial ATP production. Regulation occurs through multiple nutrient- and energy-sensitive molecular mechanisms. We explored if upregulated mRNA expression of the ...

    • Uptake and predictors of direct-acting antiviral treatment for hepatitis C among people receiving opioid agonist therapy in Sweden and Norway: a drug utilization study from 2014 to 2017 

      Aas, Christer Frode; Vold, Jørn Henrik; Skurtveit, Svetlana; Odsbu, Ingvild; Chalabianloo, Fatemeh; Lim, Aaron G.; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2020)
      Background Treatment with direct-acting antiviral agents (DAAs) offers an opportunity to eliminate hepatitis C virus (HCV) endemic among people who inject drugs (PWID) and people enrolled in opioid agonist therapy (OAT) ...

    • Urban settings do not ensure access to services: findings from the immunisation programme in Kampala Uganda 

      Babirye, Juliet N.; Engebretsen, Ingunn Marie S.; Rutebemberwa, Elizeus; Kiguli, Juliet; Nuwaha, Fred (Peer reviewed; Journal article, 2014-03-06)
      Background: Previous studies on vaccination coverage in developing countries focus on individual- and community-level barriers to routine vaccination mostly in rural settings. This paper examines health system barriers to ...

    • The urban-rural gradient in asthma: A population-based study in Northern Europe 

      Timm, Signe; Frydenberg, Morten; Janson, Christer; Campbell, Brittany; Forsberg, Bertil; Gíslason, Þórarinn; Holm, Mathias; Jõgi, Rain; Omenaas, Ernst; Sigsgaard, Torben; Svanes, Cecilie; Schlünssen, Vivi (Peer reviewed; Journal article, 2015-12-30)
      The early life environment appears to have a persistent impact on asthma risk. We hypothesize that environmental factors related to rural life mediate lower asthma prevalence in rural populations, and aimed to investigate ...

    • Urban–Rural Differences in Hip Fracture Mortality: A Nationwide NOREPOS Study 

      Solbakken, Siri Marie; Magnus, Jeanette H.; Meyer, Haakon E; Dahl, Cecilie; Stigum, Hein; Søgaard, Anne-Johanne; Holvik, Kristin; Tell, Grethe S.; Emaus, Nina; Forsmo, Siri; Gjesdal, Clara Gram; Schei, Berit; Vestergaard, Peter; Omsland, Tone Kristin (Peer reviewed; Journal article, 2019-09-09)
      Higher hip fracture incidence in urban than in rural areas has been demonstrated, but urban–rural differences in posthip fracture mortality have been less investigated, and the results are disparate. Hence, the aims of the ...

    • Ureteral access sheaths and its use in the future: A comprehensive update based on a literature review 

      De Coninck, Vincent; Somani, Bhaskar; Sener, Emre Tarik; Emiliani, Esteban; Corrales, Mariela; Jones, Charles Patrick Warburton; Pietropaolo, Amelia; Mykoniatis, Ioannis; Zeeshan Hameed, Belthangady M.; Esperto, Francesco; Proietti, Silvia; Traxer, Olivier; Keller, Etienne Xavier (Journal article; Peer reviewed, 2022-08-31)
      Ureteral access sheaths (UASs) are part of urologist’s armamentarium when performing retrograde intrarenal surgery (RIRS). Recently, the world of RIRS has changed dramatically with the development of three game-changers: ...

    • Ureteral Strictures Following Ureteroscopic Stone Treatment 

      Ulvik, Øyvind; Harneshaug, Jill-Randi; Gjengstø, Peder (Journal article; Peer reviewed, 2021)
      Background and Purpose: Ureteral stricture is a rare, but serious complication following ureteroscopy (URS) for stones. The aim of this study was to investigate how many patients ended up with a ureteral stricture after ...

    • Ureteroscopy for stone disease in the paediatric population: lessons learned and outcomes in a Nordic setting 

      Jones, Charles Patrick Warburton; Æsøy, Mathias S.; Gjengstø, Peder; Beisland, Christian; Ulvik, Øyvind (Journal article; Peer reviewed, 2022)
      Introduction: Paediatric stone disease is rare in the Nordic communities. Still, the condition can require surgical intervention in the form of ureteroscopy (URS). Here, we report outcomes achieved at a regional (tertiary) ...