Blar i Department of Clinical Science på tittel
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The effect of electroconvulsive therapy (ECT) on serum kynurenine pathway metabolites in late-life depression
(Journal article; Peer reviewed, 2023)Background: Depression is reportedly associated with alterations in kynurenine pathway metabolites (kynurenines). Several kynurenines are involved in glutamate signaling, and some have potentially neurotoxic effects while ... -
Effect of Folic Acid Supplementation on Levels of Circulating Monocyte Chemoattractant Protein-1 and the Presence of Intravascular Ultrasound Derived Virtual Histology Thin-Cap Fibroatheromas in Patients with Stable Angina Pectoris
(Peer reviewed; Journal article, 2013-07-25)Background: Virtual Histology Intravascular Ultrasound (VH–IVUS) may be used to detect early signs of unstable coronary artery disease. Monocyte Chemoattractant Protein-1 (MCP-1) is linked with coronary atherosclerosis and ... -
Effect of genetic variability in 20 pharmacogenes on concentrations of tamoxifen and its metabolites
(Journal article; Peer reviewed, 2021)Background: Tamoxifen, as a treatment of estrogen receptor positive (ER+) breast cancer, is a weak anti-estrogen that requires metabolic activation to form metabolites with higher anti-estrogenic activity. Endoxifen is the ... -
The Effect of Lean-Seafood and Non-Seafood Diets on Fasting and Postprandial Serum Metabolites and Lipid Species: Results from a Randomized Crossover Intervention Study in Healthy Adults
(Peer reviewed; Journal article, 2018-05-11)The metabolic effects associated with intake of different dietary protein sources are not well characterized. We aimed to elucidate how two diets that varied in main protein sources affected the fasting and postprandial ... -
The effect of low dose marine protein hydrolysates on short-term recovery after high intensity performance cycling: A double-blinded crossover study
(Peer reviewed; Journal article, 2019)Background: Knowledge of the effect of marine protein hydrolysate (MPH) supplementation to promote recovery after high intensity performance training is scarce. The aim of this study was to examine the effect of MPH ... -
Effect of maternal sleep on embryonic development
(Journal article; Peer reviewed, 2022)The concept of developmental origin of health and disease has ignited a search for mechanisms and health factors influencing normal intrauterine development. Sleep is a basic health factor with substantial individual ... -
Effect of Non-tuberculous Mycobacteria on Host Biomarkers Potentially Relevant for Tuberculosis Management.
(Peer reviewed; Journal article, 2014-10-16)Background Non-tuberculous mycobacteria (NTM) are different from Mycobacterium tuberculosis (MTB) both in their ubiquitous environmental distribution and in their reduced capacity to cause disease. While often neglected ... -
The Effect of Protease-Activated Receptor-1 (PAR-1) Inhibition on Endothelial-Related Biomarkers in Patients with Coronary Artery Disease
(Journal article; Peer reviewed, 2022)Background: Vorapaxar has been shown to reduce cardiovascular mortality in postmyocardial infarction (MI) patients. Pharmacodynamic biomarker research related to protease-activated receptor-1 (PAR-1) inhibition with vorapaxar ... -
Effect of Temporal and Spatial Smoothing on Speckle–Tracking‑Derived Strain in Neonates
(Journal article; Peer reviewed, 2021)Clinical application of strain in neonates requires an understanding of which image acquisition and processing parameters affect strain values. Previous studies have examined frame rate, transmitting frequency, and vendor ... -
Effect of the MDM2 promoter polymorphisms SNP309T>G and SNP285G>C on the risk of ovarian cancer in BRCA1 mutation carriers
(Peer reviewed; Journal article, 2012-10-05)Background: While BRCA mutation carriers possess a 20-40% lifetime risk of developing ovarian cancer, knowledge about genetic modifying factors influencing the phenotypic expression remains obscure. We explored the ... -
Effect of the World Health Organization Checklist on Patient Outcomes: A Stepped Wedge Cluster Randomized Controlled Trial
(Peer reviewed; Journal article, 2015-05)Objectives: We hypothesized reduction of 30 days’ in-hospital morbidity, mortality, and length of stay postimplementation of the World Health Organization’s Surgical Safety Checklist (SSC). Background: Reductions of morbidity ... -
The effect of transitions intervention to ensure patient safety and satisfaction when transferred from hospital to home health care-A systematic review
(Journal article; Peer reviewed, 2023)Aim The aim of this systematic review is to describe and evaluate the effectiveness of transition interventions to safeguard patient safety and satisfaction during patients' transition from hospital to home health ... -
The effect of WnT pathway modulators on human iPSC-derived pancreatic beta cell maturation
(Peer reviewed; Journal article, 2019-05-08)Current published protocols for targeted differentiation of human stem cells toward pancreatic β-cells fail to deliver sufficiently mature cells with functional properties comparable to human islet β-cells. We aimed to ... -
The effect of Zhang’s guideline versus the WHO partograph on childbirth experience measured by the Childbirth Experience Questionnaire in the Labor Progression Study (LaPS): A cluster randomized trial
(Journal article; Peer reviewed, 2021)Introduction Childbirth experience is an increasingly recognized and important measure of quality of obstetric care. Previous research has shown that it can be affected by intrapartum care and how labor is followed. A ... -
Effectiveness of Internet-Based Cognitive Behavioral Therapy with Telephone Support for Noncardiac Chest Pain: Randomized Controlled Trial
(Journal article; Peer reviewed, 2022)Background: Noncardiac chest pain has a high prevalence and is associated with reduced quality of life, anxiety, avoidance of physical activity, and high societal costs. There is a lack of an effective, low-cost, easy to ... -
Effectiveness, safety, and patient reported outcomes of a planned investment procedure in higher-risk chronic total occlusion percutaneous coronary intervention: Rationale and design of the invest-CTO study
(Journal article; Peer reviewed, 2023)Background: The anatomical complexity of a chronic total occlusion (CTO) correlates with procedural failure and complication rates. CTO modification after unsuccessful crossing has been associated with subsequent higher ... -
Effects of a multicomponent high intensity exercise program on physical function and health-related quality of life in older adults with or at risk of mobility disability after discharge from hospital: a randomised controlled trial
(Journal article; Peer reviewed, 2020)Background Many older people suffer from mobility limitations and reduced health-related quality of life (HRQOL) after discharge from hospital. A consensus regarding the most effective exercise-program to optimize physical ... -
Effects of anthocyanin supplementation on serum lipids, glucose, markers of inflammation and cognition in adults with increased risk of dementia - A pilot study
(Peer reviewed; Journal article, 2019-06-11)Background: Anthocyanins may protect against cardiovascular related cognitive decline and dementia. Objective: Open-label study to measure changes in serum lipids, glucose, glycosylated hemoglobin (HbA1c), and markers of ... -
Effects of applying universal fetal growth standards in a Scandinavian multi-ethnic population
(Peer reviewed; Journal article, 2018-02)Introduction: The question of whether universal growth charts can be used in multi‐ethnic settings is of general interest. The Intergrowth‐21st fetal growth and newborn size standards are suggested to represent optimal ... -
Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs
(Journal article; Peer reviewed, 2022)The Enhancing NeuroImaging Genetics through Meta-Analysis copy number variant (ENIGMA-CNV) and 22q11.2 Deletion Syndrome Working Groups (22q-ENIGMA WGs) were created to gain insight into the involvement of genetic factors ...