Blar i Department of Clinical Science på tittel
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The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
(Journal article; Peer reviewed, 2023)The International prognostic Index (IPI) is the most widely used clinical prediction model for diffuse large B-cell lymphoma (DLBCL) patients treated with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone ... -
Germline pathogenic variants in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms
(Journal article; Peer reviewed, 2023)High-grade gastroenteropancreatic (HG-GEP) neuroendocrine neoplasms (NENs) are highly aggressive cancers. The molecular etiology of these tumors remains unclear, and the prevalence of pathogenic germline variants in patients ... -
Gestational diabetes mellitus follow-up in Norwegian primary health care: a qualitative study
(Journal article; Peer reviewed, 2022)Background Women with gestational diabetes mellitus (GDM) have a tenfold increased risk of developing diabetes, and a high risk of recurrent GDM. Endorsing the life-course approach, aiming to prevent disease and promote ... -
Getting personal: Can systems medicine integrate scientific and humanistic conceptions of the patient?
(Peer reviewed; Journal article, 2014-12)Rationale, aims and objectives The practicing doctor, and most obviously the primary care clinician who encounters the full complexity of patients, faces several fundamental but intrinsically related theoretical and practical ... -
Giant right ventricular outflow tract thrombus in hereditary spherocytosis: a case report
(Peer reviewed; Journal article, 2016-04-26)Background: In hereditary spherocytosis with severe anemia, splenectomy is a recommended treatment. However, the spleen carries an important role both in immune function and coagulation. The increased risk of bacterial ... -
Giardia-specific cellular immune responses in post-giardiasis chronic fatigue syndrome
(Peer reviewed; Journal article, 2017-01-28)Background: The role of pathogen specific cellular immune responses against the eliciting pathogen in development of post-infectious chronic fatigue syndrome (PI-CFS) is not known and such studies are difficult to perform. ... -
Giardiasis : with emphasis on treatment and post-infectious manifestations
(Doctoral thesis, 2010-05-21) -
Giardiasis treatment: an update with a focus on refractory disease
(Journal article; Peer reviewed, 2020-10)Purpose of review Giardiasis remains a common cause of diarrhea and intestinal enteropathy globally. Here we give an overview of clinical treatment studies and discuss potential mechanisms and molecular targets for ... -
Global coronary artery plaque area is associated with myocardial hypoperfusion in women with non-ST elevation myocardial infarction
(Peer reviewed; Journal article, 2015-05)Background: Women with non-ST elevation myocardial infarction (NSTEMI) have similar extent of myocardial ischemia but less obstructive coronary artery disease (CAD) than their male counterparts. We tested the impact of ... -
Global left ventricular load in asymptomatic aortic stenosis: covariates and prognostic implication (the SEAS trial)
(Peer reviewed; Journal article, 2012-11-05)Introduction: Valvuloarterial impedance (Zva) is a measure of global (combined valvular and arterial) load opposing left ventricular (LV) ejection in aortic stenosis (AS). The present study identified covariates and tested ... -
Global Lung Function Initiative 2012 reference equations for spirometry in the Norwegian Population
(Peer reviewed; Journal article, 2016)We studied the fit of the Global Lung Function Initiative (GLI) all-age reference values to Norwegians, compared them with currently used references (European Community for Steel and Coal (ECSC) and Zapletal) and estimated ... -
Glucocorticoid pharmacogenetics in Addison's disease - The role of the immunophilin FK506-binding protein (FKBP51) for glucocorticoid sensitivity
(Master thesis, 2008-05-31)There is great variation in the inter-individual sensitivity to glucocorticoids. The immunophilin FK506 binding protein (FKBP51) confers short-loop negative feedback inhibition of the glucocorticoid signalling pathway. ... -
Glucocorticoid Treatment and Quality of Life in Addison’s disease
(Doctoral thesis, 2014-06-06)Addison’s disease (AD) is rare and result in lack of the adrenal hormones cortisol, aldosterone and adrenal androgens. Despite conventional oral replacement therapy, mortality is increased and Health-Related Quality-of-life ... -
Glycated albumin and continuous glucose monitoring metrics across pregnancy in women with pre-gestational diabetes
(Journal article; Peer reviewed, 2022)Introduction: Glycated albumin (GA), a biomarker reflecting short-term glycaemia, may be useful to assess glycaemic control in pregnancy. We examined the association between GA and continuous glucose monitoring (CGM) metrics ... -
Glycated albumin in pregnancy: LC-MS/MS-based reference interval in healthy, nulliparous Scandinavian women and its diagnostic accuracy in gestational diabetes mellitus
(Journal article; Peer reviewed, 2022)Glycated albumin (GA) may be a useful biomarker of glycemia in pregnancy. The aim of this study was to establish the reference interval (RI) for GA, analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS), ... -
Glycated hemoglobin and long-term prognosis in patients with suspected stable angina pectoris without diabetes mellitus: A prospective cohort study
(Peer reviewed; Journal article, 2015-05)Objective: Associations of glycated hemoglobin A1c (HbA1c) levels to incident coronary and cardiovascular events among non-diabetic patients with coronary artery disease are unclear. We investigated relations of HbA1c to ... -
GM-CSF, Flt3-L and IL-4 affect viability and function of conventional dendritic cell types 1 and 2
(Journal article; Peer reviewed, 2023-01-12)Conventional type 1 dendritic cells (cDC1) and conventional type 2 dendritic cells (cDC2) have attracted increasing attention as alternatives to monocyte-derived dendritic cells (moDCs) in cancer immunotherapy. Use of cDCs ... -
GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis
(Peer reviewed; Journal article, 2018-12-06)Autoantibodies have been associated with autoimmune diseases. However, studies have identified autoantibodies in healthy donors (HD) who do not develop autoimmune disorders. Here we provide evidence of a network of ... -
Grading of Aortic Stenosis: Is it More Complicated in Women?
(Journal article; Peer reviewed, 2022)Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and ... -
Granulocyte colony-stimulating factor alters the systemic metabolomic profile in healthy donors
(Journal article; Peer reviewed, 2017)Introduction: Peripheral blood stem cells mobilized by granulocyte colony-stimulating factor (G-CSF) from healthy donors are commonly used for allogeneic stem cell transplantation. The effect of G-CSF administration on ...