Blar i Department of Clinical Science på tittel
Viser treff 1157-1176 av 2325
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Incidence of tuberculosis among school-going adolescents in South India
(Peer reviewed; Journal article, 2016-07-26)Background: Tuberculosis (TB) incidence data in vaccine target populations, particularly adolescents, are important for designing and powering vaccine clinical trials. Little is known about the incidence of tuberculosis ... -
Incidence of tuberculosis and the influence of surveillance strategy on tuberculosis case-finding and all-cause mortality: A cluster randomised trial in Indian neonates vaccinated with BCG
(Peer reviewed; Journal article, 2019)Introduction: Accurate tuberculosis (TB) incidence and optimal surveillance strategies are pertinent to TB vaccine trial design. Infants are a targeted population for new TB vaccines, but data from India, with the highest ... -
Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients
(Peer reviewed; Journal article, 2016-09)Objectives: The objectives of this study were to estimate the impact of recruitment source and outcome definition on the incidence of acute exacerbations of COPD (AECOPD) and explore possible predictors of AECOPD. Patients ... -
Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis
(Peer reviewed; Journal article, 2017-07)Background A potential link between increase in total cholesterol and triglycerides and clinical improvement has been observed during antipsychotic drug treatment in chronic schizophrenia patients, possibly due to drug ... -
Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe
(Peer reviewed; Journal article, 2014-07-21)Background: One out of ten newly diagnosed patients in Europe was infected with a virus carrying a drug resistant mutation. We analysed the patterns over time for transmitted drug resistance mutations (TDRM) using data ... -
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
(Journal article; Peer reviewed, 2022)Background Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ... -
Increased CSF levels of aromatic amino acids in hip fracture patients with delirium suggests higher monoaminergic activity
(Peer reviewed; Journal article, 2016-08-02)Background: To examine whether delirium in hip fracture patients was associated with changes in the levels of amino acids and/or monoamine metabolites in cerebrospinal fluid (CSF) and serum. Methods: In this prospective ... -
Increased cytotoxicity and streptolysin O activity in group G streptococcal strains causing invasive tissue infections
(Peer reviewed; Journal article, 2015)Streptococcus dysgalactiae subsp. equisimilis (SDSE) has emerged as an important cause of severe skin and soft tissue infections, but little is known of the pathogenic mechanisms underlying tissue pathology. Patient samples ... -
Increased gastric chromogranin A cell density following changes to diets of patients with irritable bowel syndrome
(Peer reviewed; Journal article, 2014-11)The gut endocrine cells control and regulate several functions of the gastrointestinal tract. They have been reported to be abnormal in irritable bowel syndrome (IBS), with alterations occurring in several functions regulated ... -
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19
(Journal article; Peer reviewed, 2020-12)In SARS-CoV-2 infection there is an urgent need to identify patients that will progress to severe COVID-19 and may benefit from targeted treatment. In this study we analyzed plasma cytokines in COVID-19 patients and ... -
Increased level of acute phase reactants in patients infected with modern Mycobacterium tuberculosis genotypes in Mwanza, Tanzania
(Peer reviewed; Journal article, 2014-06-05)Background: There is increasing evidence to suggest that different Mycobacterium tuberculosis lineages cause variations in the clinical presentation of tuberculosis (TB). Certain M. tuberculosis genotypes/lineages have ... -
Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas
(Peer reviewed; Journal article, 2014)Background: We aimed to study the angiogenic profile based on histomorphological markers in endometrial carcinomas in relation to imaging parameters obtained from preoperative dynamic contrast-enhanced magnetic resonance ... -
Increased Plasma Levels of Triglyceride-Enriched Lipoproteins Associate with Systemic Inflammation, Lipopolysaccharides, and Gut Dysbiosis in Common Variable Immunodeficiency
(Journal article; Peer reviewed, 2023)Purpose: Triglycerides (TG) and their major transport lipoprotein in the circulation (VLDL) appear to be related to inflammation. Patients with common variable immunodeficiency (CVID) have inflammatory complications ... -
Increased Plasma Soluble Interleukin-2 Receptor Alpha Levels in Patients With Long-Term Type 1 Diabetes With Vascular Complications Associated With IL2RA and PTPN2 Gene Polymorphisms
(Journal article; Peer reviewed, 2020)Type 1 diabetes (T1D) is largely considered an autoimmune disease leading to the destruction of insulin-producing pancreatic β cells. Further, patients with T1D have 3–4-fold increased risk of developing micro- and ... -
Increased risk of atrial fibrillation among elderly Norwegian men with a history of long-term endurance sport practice
(Journal article; Peer reviewed, 2014)Atrial fibrillation (AF) is the most common cardiac arrhythmia. The prevalence increases with increasing age. In middle-aged men, endurance sport practice is associated with increased risk of AF but there are few studies ... -
Increased severity and mortality in adults co-infected with malaria and HIV in Maputo, Mozambique: a prospective cross-sectional study
(Peer reviewed; Journal article, 2014-02-05)Background: Co-infection with falciparum malaria and HIV-1 increases the severity and mortality of both infections in unstable malaria-transmission areas. In contrast, in stable transmission areas, HIV co-infection increases ... -
Increasing Resistance of Coagulase-Negative Staphylococci in Total Hip Arthroplasty Infections: 278 THA-Revisions due to Infection Reported to the Norwegian Arthroplasty Register from 1993 to 2007
(Peer reviewed; Journal article, 2014-10-09)We investigated bacterial findings from intraoperative tissue samples taken during revision due to infection after total hip arthroplasty (THA). The aim was to investigate whether the susceptibility patterns changed during ... -
Incremental costs of COPD exacerbations in GOLD stage 2+ COPD in ever-smokers of a general population
(Journal article; Peer reviewed, 2020-11)Objectives To estimate treatment- and productivity-related costs associated with COPD in two different samples, and to analyse the association between the costs and moderate and severe exacerbations. Methods We performed ... -
Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disorders
(Journal article; Peer reviewed, 2020)Background One third of people diagnosed with schizophrenia fail to respond adequately to antipsychotic medication, resulting in persisting disabling symptoms, higher rates of hospitalization and higher costs for society. ... -
Indoor Airborne Microbiome and Endotoxin: Meteorological Events and Occupant Characteristics Are Important Determinants
(Journal article; Peer reviewed, 2023)Airborne bacteria and endotoxin may affect asthma and allergies. However, there is limited understanding of the environmental determinants that influence them. This study investigated the airborne microbiomes in the homes ...