Blar i Department of Clinical Science på tittel
Viser treff 685-704 av 2325
-
Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition: an ESE clinical practice guideline
(Journal article; Peer reviewed, 2022)Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment but are associated with significant autoimmune endocrinopathies that pose both diagnostic and treatment challenges. The aim of this guideline is to ... -
The endogenous hallucinogen and trace amine N,N-dimethyltryptamine (DMT) displays potent protective effects against hypoxia via sigma-1 receptor activation in human primary iPSC-derived cortical neurons and microglia-like immune cells
(Peer reviewed; Journal article, 2016)N,N-dimethyltryptamine (DMT) is a potent endogenous hallucinogen present in the brain of humans and other mammals. Despite extensive research, its physiological role remains largely unknown. Recently, DMT has been found ... -
Endometrial ablation; less is more? Historical cohort study comparing long-term outcomes from two time periods and two treatment modalities for 854 women
(Peer reviewed; Journal article, 2019-07-10)Background: Abnormal uterine bleeding needs surgical treatment if medical therapy fails. After introduction of non-hysteroscopic endometrial ablation as alternative to hysteroscopic endometrial resection, we aimed to compare ... -
Endometrial carcinoma: a step closer to individualized therapy? Exploring transcriptional alterations in relation to prognostic biomarkers
(Doctoral thesis, 2013-09-30)Background: Endometrial cancer is diagnosed early and has in general a good prognosis. The more important it is to diagnose and treat the poor-prognosis cases. Therapy of endometrial carcinoma patients per today is to a ... -
Endoplasmic Reticulum Calcium Pumps and Tumor Cell Differentiation
(Journal article; Peer reviewed, 2020)Endoplasmic reticulum (ER) calcium homeostasis plays an essential role in cellular calcium signaling, intra-ER protein chaperoning and maturation, as well as in the interaction of the ER with other organelles. Calcium is ... -
Endothelial dysfunction in ME/CFS patients
(Journal article; Peer reviewed, 2023-02-02)Objective: A few earlier studies have found impaired endothelial function in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The present study investigated large-vessel and small-vessel endothelial ... -
Endurance exercise training volume is not associated with progression of coronary artery calcification
(Journal article; Peer reviewed, 2020)Background Recent cross‐sectional studies have suggested a dose‐dependent relationship between lifelong exposure to physical activity and the burden of calcified coronary artery disease (CAD). No longitudinal studies have ... -
Energy intake, nutritional status and weight reduction in patients one year after laparoscopic sleeve gastrectomy
(Peer reviewed; Journal article, 2013-07-30)Background: Laparoscopic sleeve gastrectomy (LSG) is increasingly popular due to its efficiency in reducing excess weight, however little is known about the nutritional status in patients after surgery. Purpose: To investigate ... -
Enhanced T-lymphocyte infiltration in a desmoid tumor of the thoracic wall in a young woman treated with intratumoral injections of the oncolytic peptide LTX-315: A case report
(Peer reviewed; Journal article, 2019-06-10)Background: Desmoid tumors are intermediary malignant, fibrous lesions occurring in various soft tissues. Surgical treatment is relentlessly challenging because of the propensity for local aggressive behavior and high risk ... -
Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles
(Journal article; Peer reviewed, 2018)Phenazine is known to regroup planar nitrogen-containing heterocyclic compounds. It was used here to enhance the bioavailability of the biologically important compound iodinin, which is near insoluble in aqueous solutions. ... -
Enhancing potential impact of hospital discharge interventions for patients with COPD: a qualitative systematic review
(Journal article; Peer reviewed, 2023-06-22)Background: Patients with chronic obstructive pulmonary disease (COPD) are frequently readmitted to hospital resulting in avoidable healthcare costs. Many different interventions designed to reduce hospital readmissions ... -
Enhancing Public Health Communication Regarding Vaccine Trials: Design and Development of the Pan-European VACCELERATE Toolkit
(Journal article; Peer reviewed, 2023)Background: The pan-European VACCELERATE network aims to implement the first transnational harmonized and sustainable vaccine trial Volunteer Registry, being a single entry point for potential volunteers of large-scale ... -
Enrichment of genetic markers of recent human evolution in educational and cognitive traits
(Peer reviewed; Journal article, 2018-08-22)Higher cognitive functions are regarded as one of the main distinctive traits of humans. Evidence for the cognitive evolution of human beings is mainly based on fossil records of an expanding cranium and an increasing ... -
Environmental pollutants in blood donors: The multicentre Norwegian donor study
(Journal article; Peer reviewed, 2020)Objectives The aim of this study was to measure blood concentrations of environmental pollutants in Norwegian donors and evaluate the risk of pollutant exposure through blood transfusions. Background Transfused blood ... -
Eosinophilic airway diseases: basic science, clinical manifestations and future challenges
(Journal article; Peer reviewed, 2022)Eosinophils have a broad range of functions, both homeostatic and pathological, mediated through an array of cell surface receptors and specific secretory granules that promote interactions with their microenvironment. ... -
Epicardial adipose tissue volume, plaque vulnerability and myocardial ischemia in non-obstructive coronary artery disease
(Journal article; Peer reviewed, 2023)Background Epicardial adipose tissue (EAT) accumulation has been associated with inflammation, atherosclerosis and microvascular dysfunction. Whether increased EAT volume is associated with coronary plaque vulnerability ... -
An epidemiological study on the associations between preeclampsia exposure, growth and physical activity in preschool age and subsequent allergy, asthma and lung function in late childhood
(Doctoral thesis, 2017-10-13)Background An adverse intrauterine environment may affect offspring immunology, including allergies, asthma and lung function, as well as offspring metabolism, including growth and development. A few studies have been ... -
The epidemiology and characteristics of sepsis in Norwegian hospitals
(Doctoral thesis, 2018-06-08)Background: Sepsis develops when the host’s immune response to infection becomes dysregulated to such an extent that life-threatening organ dysfunction evolves. Sepsis epidemiology is influenced by population characteristics, ... -
Epidemiology and etiology of primary ovarian insuffciency
(Doctoral thesis, 2023-03-02)Bakgrunn: Primær ovarialinsuffisiens (POI) er forårsaket av utilstrekkelig ovarieaktivitet og resulterer i for tidlig overgangsalder (alder <40 år). Diagnosen POI har livsendrende konsekvenser på grunn av infertilitet og ... -
Epidemiology and health related quality of life in hypoparathyroidism in Norway
(Peer reviewed; Journal article, 2016-08)Objective: The epidemiology of hypoparathyroidism (HP) is largely unknown. We aimed to determine prevalence, etiologies, health related quality of life (HRQOL) and treatment pattern of HP. Methods: Patients with HP and ...