Browsing Faculty of Medicine by Title

Now showing items 5428-5447 of 8877

    • Microbiota that affect risk for shigellosis in children in low-income countries 

      Lindsay, Brianna; Oundo, Joseph O.; Hossain, Mohammad Anowar; Antonio, Martin; Tamboura, Boubou; Walker, Alan W.; Paulson, Joseph N.; Parkhill, Julian; Omore, Richard; Faruque, Abu Syed Golam; Das, Suman Kumar; Ikumapayi, Usman Nurudeen; Adeyemi, Mitchell; Sanogo, Doh; Saha, Debasish; Sow, Samba O.; Farag, Tamer H.; Nasrin, Dilruba; Li, Shan; Panchalingam, Sandra; Levine, Myron M.; Kotloff, Karen; Magder, Laurence S.; Hungerford, Laura L.; Sommerfelt, Halvor; Pop, Mihai; Nataro, James Paul; Stine, Oscar Colin (Peer reviewed; Journal article, 2015)
      Pathogens in the gastrointestinal tract exist within a vast population of microbes. We examined associations between pathogens and composition of gut microbiota as they relate to Shigella spp./enteroinvasive Escherichia ...

    • Microemboli detection in acute ischemic stroke 

      Aarli, Sander Johan (Doctoral thesis, 2021-12-10)
      Microembolic signals (MES) are detectable by transcranial Doppler monitoring and represent small, clinically silent particles in the cerebral circulation. MES are related to increased risk of first or recurrent ischemic ...

    • Microemboli-monitoring during the acute phase of ischemic stroke: Is it worth the time? 

      Idicula, Titto T.; Næss, Halvor; Thomassen, Lars (Peer reviewed; Journal article, 2010-09-10)
      Background The prevalence of microembolic signals (MES) during the acute phase of ischemic stroke and its influence on outcome is not well studied. The aim of our study was to determine the prevalence of MES, the different ...

    • The microenvironment in human ovarian carcinoma - characterization through proteomic analysis of tissue interstitial fluid 

      Haslene-Hox, Hanne (Doctoral thesis, 2013-10-11)
      The interstitial fluid of tissues and that of tumors in particular, represents the secretome and is thus a valuable source of tissue-specific proteins. The differential expression of proteins that are secreted in tumor ...

    • Microfilaments in cells associated with induced heterotpic bone formation in guinea pigs 

      Nilsen, Rune (Journal article, 1980)
      Sera from active chronic hepatitis were used to demonstrate actin microfilaments in cells of a bone-induced model. Demnineralized and freeze-dried allogenic dentine was implanted in the abdominal muscles of Guinea pigs. ...

    • Microfluidics for studying metastatic patterns of lung cancer 

      Ruzycka, Monika; Cimpan, Mihaela Roxana; Rios Mondragon, Ivan; Grudzinski, Ireneusz (Peer reviewed; Journal article, 2019-05-27)
      The incidence of lung cancer continues to rise worldwide. Because the aggressive metastasis of lung cancer cells is the major drawback of successful therapies, the crucial challenge of modern nanomedicine is to develop ...

    • Microheterogeneity and preanalytical stability of protein biomarkers of inflammation and renal function 

      Gao, Jie; Ulvik, Arve; McCann, Adrian; Ueland, Per Magne; Meyer, Klaus (Journal article; Peer reviewed, 2021)
      Protein biomarker microheterogeneity has attracted increasing attention in epidemiological and clinical research studies. Knowledge concerning the preanalytical stability of proteins is paramount to assess the biological ...

    • Micronutrients in paediatric Intestinal Failure Patients receiving home parenteral nutrition 

      Thomassen, Rut Anne; Kvammen, Janne Anita; Sæland, Camilla; Kjeserud, Christina; Eikeland, Joakim; Juliusson, Petur Benedikt; Bentsen, Beint Sigmund; Henriksen, Christine (Journal article; Peer reviewed, 2020-11)
      Background & aims Children with intestinal failure (IF) receive parental nutrition to ensure adequate growth and development. The aim of this study was to assess micronutrient status in paediatric IF patients receiving ...

    • Microplastic studies in humans: evidence from feces and effects in blood 

      Mastad, Oda Cathrine Lunne (Master thesis, 2022-06-10)

    • MicroRNA Alterations and Associated Aberrant DNA Methylation Patterns across Multiple Sample Types in Oral Squamous Cell Carcinoma 

      Wiklund, Erik D.; Gao, Shan; Hulf, Toby; Sibbritt, Tennille; Nair, Shalima; Costea, Daniela Elena; Villadsen, Sune B.; Bakholdt, Vivi; Bramsen, Jesper B.; Sørensen, Jens A.; Krogdahl, Annelise; Clark, Susan J.; Kjems, Jørgen (Peer reviewed; Journal article, 2011-11-22)
      Background: MicroRNA (miRNA) expression is broadly altered in cancer, but few studies have investigated miRNA deregulation in oral squamous cell carcinoma (OSCC). Epigenetic mechanisms are involved in the regulation of .30 ...

    • A MicroRNA Linking Human Positive Selection and Metabolic Disorders 

      Wang, Lifeng; Sinnott-Armstrong, Nicholas A; Wagschal, Alexandre; Wark, Abigail R.; Camporez, Joao-Paulo; Perry, Rachel J.; Ji, Fei; Sohn, Yoojin; Oh, Justin; Wu, Su; Chery, Jessica; Moud, Bahareh Nemati; Saadat, Alham; Dankel, Simon N; Mellgren, Gunnar; Tallapragada, Divya Sri Priyanka; Strobel, Sophie Madlen; Lee, Mi-Jeong; Tewhey, Ryan; Sabeti, Pardis C.; Schaefer, Anne; Petri, Andreas; Kauppinen, Sakari; Chung, Raymond T.; Soukas, Alexander; Avruch, Joseph; Fried, Susan K.; Hauner, Hans; Sadreyev, Ruslan I.; Shulman, Gerald I.; Claussnitzer, Melina; Näär, Anders M. (Journal article; Peer reviewed, 2020)
      Positive selection in Europeans at the 2q21.3 locus harboring the lactase gene has been attributed to selection for the ability of adults to digest milk to survive famine in ancient times. However, the 2q21.3 locus is also ...

    • MicroRNA Regulation of the Synaptic Plasticity-Related Gene Arc 

      Wibrand, Karin; Pai, Balagopal; Siripornmongcolchai, Taweeporn; Bittins, Margarethe; Berentsen, Birgitte; Ofte, May Lillian; Weigel, Arwed; Skaftnesmo, Kai Ove; Bramham, Clive R. (Peer reviewed; Journal article, 2012-07-26)
      Expression of activity-regulated cytoskeleton associated protein (Arc) is crucial for diverse types of experience-dependent synaptic plasticity and long-term memory in mammals. However, the mechanisms governing Arc-specific ...

    • MicroRNA serum profiles and chronic graft-versus-host disease 

      Reikvam, Håkon; Vo, Anh Khoi; Johansen, Silje; Hemsing, Anette Lodvir; Haugland Solheim, Magne; Mosevoll, Knut Anders; Tvedt, Tor Henrik Anderson; Hatfield, Kimberley Joanne (Journal article; Peer reviewed, 2022)
      Chronic graft-versus-host disease (cGVHD) is the most common long-term complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). During the last decade, the interest of micro RNAs (miRNAs) in the ...

    • MicroRNA-138 abates fibroblast motility with effect on invasion of adjacent cancer cells 

      Rajthala, Saroj; Parajuli, Himalaya; Dongre, Harsh Nitin; Ljøkjel, Borghild; Hoven, Kristin Marie; Kvalheim, Arild; Lybak, Stein; Neppelberg, Evelyn; Sapkota, Dipak; Johannessen, Anne Christine; Costea, Daniela Elena (Journal article; Peer reviewed, 2022-03-17)
      Background: Recent studies have shown aberrant expression of micro-RNAs in cancer-associated fibroblasts (CAFs). This study aimed to investigate miR-138 dysregulation in CAFs in oral squamous cell carcinoma (OSCC) and its ...

    • MicroRNAs as important players and biomarkers in oral carcinogenesis 

      Min, Anjie; Zhu, Chao; Peng, Shuping; Rajthala, Saroj; Costea, Daniela Elena; Sapkota, Dipak (Peer reviewed; Journal article, 2015)
      Oral cancer, represented mainly by oral squamous cell carcinoma (OSCC), is the eighth most common type of human cancer worldwide. The number of new OSCC cases is increasing worldwide, especially in the low-income countries, ...

    • MicroRNAs enrichment in GWAS of complex human phenotypes 

      Goulart, Luiz Fernando De Souza; Bettella, Franscesco; Sønderby, Ida Elken; Schork, AJ; Thompson, Kurt Wesley; Mattingsdal, Morten; Steen, Vidar Martin; Zuber, Verena; Wang, Yunpeng; Dale, Anders; Andreassen, Ole Andreas; Djurovic, Srdjan (Peer reviewed; Journal article, 2015-04-16)
      Background: The genotype information carried by Genome-wide association studies (GWAS) seems to have the potential to explain more of the ‘missing heritability’ of complex human phenotypes, given improved statistical ...

    • MicroRNAs in Differentiation of Embryoid Bodies and the Teratoma Subtype of Testicular Cancer 

      Myklebust, Mette Pernille; Søviknes, Anne Mette; Halvorsen, Ole Johan; Thor, Anna; Dahl, Olav; Ræder, Helge (Journal article; Peer reviewed, 2022)
      Background: Testicular germ cell tumours (TGCTs) are the most frequent tumour type among young, adult men. TGCTs can be efficiently treated, but metastases of the teratoma subtype, for which there are no circulating ...

    • Microsatellite instability at tetranucleotides (EMAST) in colorectal cancer: clinical relevance, mechanisms and immune markers 

      Watson, Martin M (Doctoral thesis, 2020-06-18)
      Colorectal cancer (CRC) is the second-leading cause of cancer-related death and a global burden in terms of incidence, person-years of life lost and public health costs. About 10-20% of sporadic CRCs develop through a ...

    • Microsphere cytometry to interrogate microenvironment-dependent cell signaling 

      Ertsås, Henriette Christie; Nolan, Garry P.; LaBarge, Mark A.; Lorens, James (Journal article; Peer reviewed, 2017)
      Microenvironmental cues comprising surface-mediated and soluble factors control cellular signaling mechanisms underlying normal cellular responses that define homeostatic and diseased cell states. In order to measure cell ...

    • Microvascular proliferation in luminal Aand basal-like breast cancer subtypes 

      Kraby, Maria Ryssdal; Krüger, Kristi; Opdahl, Signe; Vatten, Lars Johan; Akslen, Lars A.; Bofin, Anna M. (Peer reviewed; Journal article, 2015)
      Aims: The aims of this study were to examine microvessel density (MVD), proliferating MVD (pMVD) and Vascular Proliferation Index (VPI) in basal-like phenotype (BP) and luminal A subtypes of breast cancer and to study their ...