Blar i Faculty of Medicine på tittel
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Fotokjemisk internalisering (PCI) av HER2-rettet immunotoksin; trastuzumab-saporin
(Master thesis, 2009-05-19)En begrensning for terapeutisk nytte av makromolekyler som utøver sin effekt intracellulært er at de etter opptak ved endocytose degraderes lysosomalt før de når sitt terapeutiske mål i cytosol. Fotokjemisk internalisering ... -
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
(Peer reviewed; Journal article, 2017)A meta-analysis of publicly available summary statistics on multiple sclerosis combined with three Nordic multiple sclerosis cohorts (21,079 cases, 371,198 controls) revealed seven sequence variants associating with multiple ... -
FOXC2 expression and epithelial–mesenchymal phenotypes are associated with castration resistance, metastasis and survival in prostate cancer
(Peer reviewed; Journal article, 2019)Epithelial–mesenchymal transition (EMT) is important for tumour cell invasion and metastasis and is a feature of aggressive carcinomas. EMT is characterised by reduced E‐cadherin and increased N‐cadherin expression ... -
Fra skjema til system. En kvalitativ studie av leders erfaringer med kvalitetssystem som styringsredskap
(Master thesis, 2023-06-15)Bakgrunn: Kvalitetsforbedringsforskriften stiller krav om systematisk forbedring, kvalitet, system og kultur. Et velfungerende kvalitetssystem er en forutsetning for effektiv virksomhetsstyring. I 2019 ble et elektronisk ... -
Fra sosialproblem til helseproblem? En praxeologisk analyse av narkotikapolitikken i Norge
(Master thesis, 2017-06-21)I denne oppgaven søker jeg å beskrive narkotikafeltets utvikling i Norge, gjennom registrantanalyse av stortingsmeldinger og andre statlige dokumenter fra 1960-tallet og frem til 2012. Jeg forsøker å avdekke feltets struktur, ... -
Fractional anisotropy shows differential reduction in frontal-subcortical fiber bundles - A longitudinal MRI study of 76 middle-aged and older adults
(Peer reviewed; Journal article, 2015-05-15)Motivated by the frontal- and white matter (WM) retrogenesis hypotheses and the assumptions that fronto-striatal circuits are especially vulnerable in normal aging, the goal of the present study was to identify fiber bundles ... -
Fractional exhaled nitric oxide among cement factory workers: a cross sectional study
(Peer reviewed; Journal article, 2013-05)Background: It has been suggested that dust exposure causes airway inflammation among cement factory workers. However, there is limited information on the mechanisms of this effect. We explored any associations between ... -
Fractographic analysis of 35 clinically fractured bi-layered and monolithic zirconia crowns
(Journal article; Peer reviewed, 2022)Objectives The aim of this retrieval study was to analyze the fracture features and identify the fracture origin of zirconia-based single crowns that failed during clinical use. Methods Thirty-five fractured single crowns ... -
Fractographic features of glass-ceramic and zirconia-based dental restorations fractured during clinical function
(Peer reviewed; Journal article, 2014-04-04)Fractures during clinical function have been reported as the major concern associated with all-ceramic dental restorations. The aim of this study was to analyze the fracture features of glass-ceramic and zirconia-based ... -
Fracture resistance of simulated immature teeth treated with a regenerative endodontic protocol
(Peer reviewed; Journal article, 2019)This study aims to evaluate fracture resistance of simulated immature teeth after treatment with regenerative endodontic procedure (REP) using tricalcium silicate cements (TSCs) as cervical plugs. Bovine incisors were ... -
Fracture-related infection: Prevalence and application of the new consensus definition in a cohort of 1004 surgically treated ankle fractures
(Journal article; Peer reviewed, 2023)Background Surgical treatment of ankle fractures comes with a substantial risk of complications, including infection. An unambiguously definition of fracture-related infections (FRI) has been missing. Recently, FRI has ... -
Fractures diagnosed in primary care – a five-year retrospective observational study from a Norwegian rural municipality with a ski resort
(Peer reviewed; Journal article, 2019-11-13)Objective: The aim of this study was to characterize fractures recorded at a Norwegian primary care centre near a ski resort. Design: A retrospective five-year observational study in the period 2010–2014. Setting: A primary ... -
Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97
(Journal article; Peer reviewed, 2022)Biosensor techniques have become increasingly important for fragment-based drug discovery during the last years. The AAA+ ATPase p97 is an essential protein with key roles in protein homeostasis and a possible target for ... -
Frailty and survival in elderly intensive care patients in Norway
(Journal article; Peer reviewed, 2021)Background Today, 10%-15% of Norwegian intensive care patients are ≥80 years. This proportion will increase significantly over the next 20 years, but it is unlikely that resources for intensive care increase correspondingly. ... -
Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer’s Disease
(Peer reviewed; Journal article, 2019)Introduction: The aim of the study is to describe the frequency of frailty in people with a new diagnosis of mild dementia due to Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). Methods: This is a secondary ... -
Frailty’s influence on 30-day mortality in old critically ill ICU patients: a bayesian analysis evaluating the clinical frailty scale
(Journal article; Peer reviewed, 2023)Introduction Frailty is widely acknowledged as influencing health outcomes among critically ill old patients. Yet, the traditional understanding of its impact has predominantly been through frequentist statistics. We ... -
Frakturer i prosessus condylaris mandibula. Litteraturstudie og kliniske kasuistikker
(Master thesis, 2009-03-27)Fractures of the mandibular condyle are the most common fracture in mandibula, and are often caused by trauma. We hereby present the incidence of these fractures in the mandible, diagnosis and classification. Condylar neck ... -
Free-Market Illusions: Health Sector Reforms In Uganda 1987–2007
(Doctoral thesis, 2009-10-30)Introduction: By the late 1980s, Uganda’s health system had been devastated by two decades of conflict and mismanagement. At the same time, public-funded and run health systems had begun to be viewed as inefficient and ... -
Freely distributed bed-net use among Chano Mille residents, south Ethiopia: a longitudinal study
(Peer reviewed; Journal article, 2013-01-18)Background: A huge discrepancy was reported between ownership versus utilization of insecticide-treated bed nets (ITNs). To acquire the benefits of ITNs, households need to use and not merely own them. The objective of ... -
The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy Indian adolescents
(Peer reviewed; Journal article, 2014-07-03)Background: QuantiFERON-TB Gold In-Tube (QFT) is an IFNγ-release assay used in the diagnosis of Mycobacterium tuberculosis (MTB) infection. The risk of TB progression increases with the magnitude of the MTB-specific ...