Blar i Faculty of Medicine på tittel

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    • Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk 

      Shrine, Nick; Izquierdo, Abril G.; Chen, Jing; Packer, Richard; Hall, Robert J.; Guyatt, Anna L.; Batini, Chiara; Thompson, Rebecca J.; Pavuluri, Chandan; Malik, Vidhi; Hobbs, Brian D.; Moll, Matthew; Kim, Wonji; Tal-Singer, Ruth; Bakke, Per S.; Fawcett, Katherine A.; John, Catherine; Coley, Kayesha; Piga, Noemi Nicole; Pozarickij, Alfred; Lin, Kuang; Millwood, Iona Y.; Chen, Zhengming; Li, Liming; Wijnant, Sara R A; Lahousse, Lies; Brusselle, Guy; Uitterlinden, Andre G.; Manichaikul, Ani; Oelsner, Elizabeth C.; Rich, Stephen S.; Barr, R Graham; Kerr, Shona M.; Vitart, Veronique; Brown, Michael R.; Wielscher, Matthias; Imboden, Medea; Jeong, Ayoung; Bartz, Traci M.; Gharib, Sina A.; Flexeder, Claudia; Karrasch, Stefan; Gieger, Christian; Peters, Annette; Stubbe, Beate; Hu, Xiaowei; Ortega, Victor E.; Meyers, Deborah A.; Bleecker, Eugene R.; Gabriel, Stacey B.; Gupta, Namrata; Smith, Albert Vernon; Luan, Jian'an; Zhao, Jing-Hua; Hansen, Ailin Falkmo; Langhammer, Arnulf; Willer, Cristen; Bhatta, Laxmi; Porteous, David; Smith, Blair H.; Campbell, Archie; Sofer, Tamar; Lee, Jiwon; Daviglus, Martha L.; Yu, Bing; Lim, Elise; Xu, Hanfei; O'Connor, George T.; Thareja, Gaurav; Albagha, Omar M E; Suhre, Karsten; Granell, Raquel; Faquih, Tariq O.; Hiemstra, Pieter S.; Slats, Annelies M.; Mullin, Benjamin H.; Hui, Jennie; James, Alan; Beilby, John; Patasova, Karina; Hysi, Pirro; Koskela, Jukka T.; Wyss, Annah B.; Jin, Jianping; Sikdar, Sinjini; Lee, Mikyeong; May-Wilson, Sebastian; Pirastu, Nicola; Kentistou, Katherine A.; Joshi, Peter K.; Timmers, Paul R H J; Williams, Alexander T.; Free, Robert C.; Wang, Xueyang; Morrison, John L.; Gilliland, Frank D.; Chen, Zhanghua; Wang, Carol A.; Foong, Rachel E.; Harris, Sarah E.; Taylor, Adele; Redmond, Paul; Cook, James P.; Mahajan, Anubha; Lind, Lars; Palviainen, Teemu; Lehtimäki, Terho; Raitakari, Olli T.; Kaprio, Jaakko; Rantanen, Taina; Pietiläinen, Kirsi H.; Cox, Simon R.; Pennell, Craig E.; Hall, Graham L.; Gauderman, W James; Brightling, Chris; Wilson, James F.; Vasankari, Tuula; Laitinen, Tarja; Salomaa, Veikko; Mook-Kanamori, Dennis O.; Timpson, Nicholas J.; Zeggini, Eleftheria; Dupuis, Josée; Hayward, Caroline; Brumpton, Ben Michael; Langenberg, Claudia; Weiss, Stefan; Homuth, Georg; Schmidt, Carsten Oliver; Probst-Hensch, Nicole; Jarvelin, Marjo-Riitta; Morrison, Alanna C.; Polasek, Ozren; Rudan, Igor; Lee, Joo-Hyeon; Sayers, Ian; Rawlins, Emma L.; Dudbridge, Frank; Silverman, Edwin K.; Strachan, David P.; Walters, Robin G.; Morris, Andrew P.; London, Stephanie J.; Cho, Michael H.; Wain, Louise V.; Hall, Ian P.; Tobin, Martin D. (Journal article; Peer reviewed, 2023)
      Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 ...

    • A multi-layer perceptron network for perfusion parameter estimation in DCE-MRI studies of the healthy kidney 

      Klepaczko, Artur; Strzelecki, Michał; Kociołek, Marcin; Eikefjord, Eli Bjøvad; Lundervold, Arvid (Journal article; Peer reviewed, 2020)
      Background: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is an imaging technique which helps in visualizing and quantifying perfusion—one of the most important indicators of an organ’s state. This paper ...

    • Multi-Level Communication of Human Retinal Pigment Epithelial Cells via Tunneling Nanotubes 

      Wittig, Dierk; Wang, Xiang; Walter, Cindy; Gerdes, Hans-Hermann; Funk, Richard H. W.; Roehlecke, Cora (Peer reviewed; Journal article, 2012-03-22)
      Background: Tunneling nanotubes (TNTs) may offer a very specific and effective way of intercellular communication. Here we investigated TNTs in the human retinal pigment epithelial (RPE) cell line ARPE-19. Morphology of ...

    • Multi-national Gene Expression Profiling of Oral Squamous Cell Carcinomas. Biological Pathways Regardless of Differences Related to Life-style and Ethnicity 

      Lunde, Mai Lill Suhr (Doctoral thesis, 2012-02-02)
      Oral squamous cell carcinoma (OSCC) is a major health problem in many developing countries, representing more than 25% of all new cancer cases in some countries such as India and Sri Lanka. Cigarette smoking, smokeless ...

    • Multi-omics and machine learning for the prevention and management of female reproductive health 

      Kharb, Simmi; Joshi, Anagha (Journal article; Peer reviewed, 2023)
      Females typically carry most of the burden of reproduction in mammals. In humans, this burden is exacerbated further, as the evolutionary advantage of a large and complex human brain came at a great cost of women’s ...

    • Multi-psychotropic drug prescription and the association to neuropsychiatric symptoms in three Norwegian nursing home cohorts between 2004 and 2011 

      Gulla, Christine; Selbaek, Geir; Flo, Elisabeth; Kjome, Reidun Lisbet Skeide; Kirkevold, Øyvind; Husebø, Bettina (Peer reviewed; Journal article, 2016-06-01)
      Background Neuropsychiatric symptoms, such as affective symptoms, psychosis, agitation, and apathy are common among nursing home patients with and without dementia. Treatment with one or more psychotropic drug is often ...

    • Multi-Wavelength Photobiomodulation Therapy Combined with Static Magnetic Field on Long-Term Pulmonary Complication after COVID-19: A Case Report 

      Tomazoni, Shaiane Silva; Johnson, Douglas Scott; Leal, Ernesto Cesar Pinto Jr (Journal article; Peer reviewed, 2021)
      Introduction: Photobiomodulation therapy, alone (PBMT) or combined with a static magnetic field (PBMT-sMF), has been demonstrated to be effective in the regeneration of tissues, modulation of inflammatory processes, and ...

    • A multicenter study on Leigh syndrome: disease course and predictors of survival 

      Sofou, Kalliopi; De Coo, Irenaeus F. M.; Isohanni, Pirjo; Ostergaard, Elsebet; Naess, Karin; De Meirleir, Linda; Tzoulis, Charalampos; Uusimaa, Johanna; De Angst, Isabell B.; Lönnqvist, Tuula; Pihko, Helena; Mankinen, Katariina; Bindoff, Laurence; Tulinius, Már; Darin, Niklas (Peer reviewed; Journal article, 2014-04-15)
      Background: Leigh syndrome is a progressive neurodegenerative disorder, associated with primary or secondary dysfunction of the mitochondrial oxidative phosphorylation. Despite the fact that Leigh syndrome is the most ...

    • A multicomponent intervention to optimise nurseepatient communication in the intensive care unit: A mixed-methods acceptability and feasibility study 

      Holm, Anna; Nikolajsen, Lone; Dreyer, Pia (Journal article; Peer reviewed, 2021)
      Background Mechanically ventilated patients in intensive care units may experience communication challenges owing to intubation, which affects nurse–patient communication. Several strategies may optimise communication, ...

    • The multidimensional fatigue inventory (MFI-20): psychometrical testing in a Norwegian sample of inflammatory bowel disease (IBD) patients 

      Jelsness-Jørgensen, Lars-Petter; Moum, Bjørn Allan; Grimstad, Tore Bjørn; Jahnsen, Jørgen; Hovde, Øistein; Frigstad, Svein Oskar; Bernklev, Tomm (Journal article; Peer reviewed, 2022)
      OBJECTIVES To evaluate the psychometric properties of the Norwegian version of the multidimensional fatigue inventory (MFI-20) in patients with inflammatory bowel disease. METHODS Participants were recruited from nine ...

    • Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort 

      Fretheim, Håvard Halland; Halse, Anne-Kristine; Seip, Marit; Bitter, Helle; Wallenius, Marianne; Garen, Torhild Oddveig; Salberg, Anne; Brunborg, Cathrine; Midtvedt, Øyvind; Molberg, Øyvind; Hoffmann-Vold, Anna-Maria (Journal article; Peer reviewed, 2020)
      Objective SSc is a severe, heterogeneous multi-organ disease where population-based estimates on phenotypic spectrum, overall disease burden and societal impact are largely missing. Here the objective was to provide the ...

    • Multidimensjonal stratifisert behandling av uspesifikke korsryggsmerter: en systematisk oversikt 

      Berge, Alexander Emil (Master thesis, 2016-10-31)
      Studiedesign: Systematic review. Background: Non-specific low back pain (NSLBP) is a heterogeneous condition that has proven difficult to treat. To increase treatment effects stratified care is regarded as a promising ...

    • Multidisciplinary approaches to identifying and managing global airways disease: Expert recommendations based on qualitative discussions 

      Backer, Vibeke; Cardell, Lars Olaf; Lehtimäki, Lauri; Toppila-Salmi, Sanna K.; Bjermer, Leif; Reitsma, Sietze; Hellings, Peter Wim; Weinfeld, Dan; Aanæs, Kasper; Ulrik, Charlotte Suppli; Braunstahl, Gert-Jan; Aarli, Bernt Bøgvald; Danielsen, Arild; Kankaanranta, Hannu; Steinsvåg, Sverre Karmhus; Bachert, Claus (Journal article; Peer reviewed, 2023)
      Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently co-exist and share pathologic features. Taking a “global” treatment approach benefits diagnosis and treatment of both, but care is often ...

    • Multidisciplinary intervention versus brief intervention in specialist healthcare. Attempting to improve outcomes for patients on sick leave with musculoskeletal pain 

      Brendbekken, Randi (Doctoral thesis, 2018-12-11)
      Background: Musculoskeletal pain (MSK), such as low back pain (LBP), neck pain and widespread pain, is among the most common health problems in industrial countries. Subsequently, MSK is associated with substantial healthcare ...

    • Multifaceted intervention including Facebook-groups to improve guideline-adherence in ICU: A quasi-experimental interrupted time series study 

      Petosic, Antonija; Småstuen, Milada C.; Beeckman, Dimitri; Flaatten, Hans; Sunde, Kjetil; Wøien, Hilde (Journal article; Peer reviewed, 2021)
      Background: The impact of social media, with its speed, reach and accessibility, in interventions aimed to improve adherence to guidelines such as assessment of Pain, Agitation/Sedation and Delirium (PAD) in intensive care ...

    • Multifasettert analyse av stabilitet og reologiske egenskaper i forbindelse med formulering av karbamidkremer 

      Alim, Adila (Master thesis, 2023-06-06)
      Karbamidkrem har bred klinisk anvendelse innen dermatologi for behandling av tørr hud, kløe og atopisk eksem, takket være dens fuktighetsgivende og keratolytiske egenskaper. Kremformuleringer er imidlertid termodynamisk ...

    • Multilevel analyses of related public health indicators: The European Surveillance of Congenital Anomalies (EUROCAT) Public Health Indicators 

      Best, Kate E.; Rankin, Judith; Dolk, Helen; Loane, Maria; Haeusler, Martin; Nelen, Vera; Verellen-Dumoulin, Christine; Garne, Ester; Sayers, Gerardine; Mullaney, Carmel; O'Mahony, Mary; Gatt, Miriam; de Walle, Hermien; Klungsøyr, Kari; Mokoroa, Olatz; Cavero-Carbonell, Clara; Kurinczuk, Jennifer J.; Draper, Elizabeth S.; Tucker, David; Wellesley, Diana; Zymak-Zakutnia, Natalya; Lelong, Nathalie; Khoshnood, Babak (Journal article; Peer reviewed, 2020)
      Background Public health organisations use public health indicators to guide health policy. Joint analysis of multiple public health indicators can provide a more comprehensive understanding of what they are intended to ...

    • A multilevel, step-based model to evaluate progress in procedure efficiency for laparoscopic appendicectomy in surgical training: structured evaluation using 'ebb-and-flow' and 'string-of-pearls' concepts 

      Søreide, Kjetil; Skjold-Ødegaard, Benedicte (Journal article; Peer reviewed, 2022)
      Background Surgical training is aimed towards entrusted professional activity to obtain operative independence. Laparoscopic appendicectomy is performed early in training but except for simulators, real-life evaluation ...

    • Multilocus analysis of SNP and metabolic data within a given pathway 

      Kristensen, Vessela N.; Tsalenko, Anya; Geisler, Jürgen; Faldaas, Anne; Grenaker, Grethe Irene; Lingjærde, Ole Christian; Fjeldstad, Ståle; Yakhini, Zohar; Lønning, Per Eystein; Børresen-Dale, Anne-Lise (BMC Genomics 7(5), Peer reviewed; Journal article, 2006-01-13)
      Background: Complex traits, which are under the influence of multiple and possibly interacting genes, have become a subject of new statistical methodological research. One of the greatest challenges facing human geneticists ...

    • Multimarker profiling identifies protective and harmful immune processes in heart failure: Findings from BIOSTAT-CHF 

      Markousis-Mavrogenis, George; Tromp, Jasper; Ouwerkerk, Wouter; Ferreira, João Pedro; Anker, Stefan D; Cleland, John G; Dickstein, Kenneth; Filippatos, Gerasimos; Lang, Chim C; Metra, Marco; Samani, Nilesh J; De Boer, Rudolf A; Van Veldhuisen, Dirk J; Voors, Adriaan A; Van Der Meer, Peter (Journal article; Peer reviewed, 2022)
      Aims The exploration of novel immunomodulatory interventions to improve outcome in heart failure (HF) is hampered by the complexity/redundancies of inflammatory pathways, which remain poorly understood. We thus aimed to ...