Browsing Department of Clinical Medicine by Title
Now showing items 61-80 of 2066
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Alterations of the retinoblastoma gene in metastatic breast cancer
(Peer reviewed; Journal article, 2011-01-21)Germline mutations affecting the retinoblastoma gene (RB1) predispose to inherited retinoblastomas but also other malignancies, including breast cancer. While somatic RB1 mutations have been detected in different malignancies, ... -
Altered levels of cytokines in patients with irritable bowel syndrome are not correlated with fatigue
(Peer reviewed; Journal article, 2018-07-06)Introduction: A considerable number of patients with gastrointestinal complaints attributable to irritable bowel syndrome (IBS) have shown evidence of immune activation. Fatigue is also frequently reported by IBS patients ... -
Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson's disease
(Journal article; Peer reviewed, 2023)Aberrant proteostasis is thought to be implicated in Parkinson’s disease (PD), but patient-derived evidence is scant. We hypothesized that impaired proteostasis is reflected as altered transcriptome-proteome correlation ... -
Amelioration of Severe TNBS Induced Colitis by Novel AP-1 and NF-κB Inhibitors in Rats
(Peer reviewed; Journal article, 2014-01-30)AP-1 and NF-κB inhibitors, namely, DTCM-G and DHMEQ, were investigated in male Wistar rats with severe colitis, induced by TNBS. The animals were randomized into 3 groups. The control group received 0.5 mL of 0.5% of the ... -
Amoxicillin did not Reduce Modic Change Oedema in Patients with Chronic Low Back pain - subgroup Analyses of a Randomised Trial (the AIM study)
(Journal article; Peer reviewed, 2022)Study Design. Exploratory subgroup analyses of a randomised trial [Antibiotics in Modic changes (AIM) study]. Objective. The aim was to assess the effect of amoxicillin versus placebo in reducing Modic change (MC) ... -
An exploration of the sustainability of dinner recipes
(Master thesis, 2022-05-13) -
Analysis of mortality metrics associated with a comprehensive range of disorders in Denmark, 2000 to 2018: A population-based cohort study
(Journal article; Peer reviewed, 2022-06-16)Background: The provision of different types of mortality metrics (e.g., mortality rate ratios [MRRs] and life expectancy) allows the research community to access a more informative set of health metrics. The aim of this ... -
Analysis of salivary mycobiome in a cohort of oral squamous cell carcinoma patients from Sudan identifies higher salivary carriage of malassezia as an independent and favorable predictor of overall survival
(Journal article; Peer reviewed, 2021-10-12)Background: Microbial dysbiosis and microbiome-induced inflammation have emerged as important factors in oral squamous cell carcinoma (OSCC) tumorigenesis during the last two decades. However, the “rare biosphere” of the ... -
Anaphylaxis following prick-by-prick testing with peanut
(Journal article; Peer reviewed, 2020)Anaphylaxis due to prick‐by‐prick testing is a rare but potentially life‐threatening complication. Personnel performing testing should be able to recognize and treat anaphylaxis. Adrenaline must be available. In high‐risk ... -
Anastomotic leak after surgery for colon cancer and effect on long‐term survival
(Journal article; Peer reviewed, 2020)Aim An anastomotic leak after surgery for colon cancer is a recognized complication but how it may adversely affect long‐term survival is less clear because data are scarce. The aim of the study was to investigate the ... -
The anatomic centers of the femoral and tibial insertions of the anterior cruciate ligament: a systematic review of imaging and cadaveric studies reporting normal center locations
(Journal article; Peer reviewed, 2016)Background: The anterior cruciate ligament (ACL) is regularly reconstructed if knee joint function is impaired. Anatomic graft tunnel placement, often assessed with varying measurement methods, in the femur and tibia is ... -
ANCA-associated glomerulonephritis. Prognostic factors and outcome in a Norwegian cohort
(Doctoral thesis, 2018-02-16)Objective. The objective of this dissertation is to (I) explore the temporal survival and identify prognostic factors in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis with renal affection, ... -
The ANeED study – ambroxol in new and early dementia with Lewy bodies (DLB): protocol for a phase IIa multicentre, randomised, double-blinded and placebo-controlled trial
(Journal article; Peer reviewed, 2023-05-26)Background: Currently, there are no disease-modifying pharmacological treatment options for dementia with Lewy bodies (DLB). The hallmark of DLB is pathological alpha-synuclein (aS) deposition. There are growing amounts ... -
Animal Laboratory Training Improves Lung Ultrasound Proficiency and Speed
(Peer reviewed; Journal article, 2013-09)Background: Although lung ultrasound (US) is accurate in diagnosing pneumothorax (PTX), the training requirements and methods necessary to perform US examinations must be defined. Objective: Our aim was to test whether ... -
Animal versus plant-based protein and risk of cardiovascular disease and type 2 diabetes: a systematic review of randomized controlled trials and prospective cohor t studies
(Journal article; Peer reviewed, 2023)Objectives: To systematically review the evidence on the effect of replacing the intake of animal protein with plant protein on cardiovascular disease (CVD) and type 2 diabetes (T2D) and their intermediate risk ... -
Ankle fractures: a systematic review of patient‑reported outcome measures and their measurement properties
(Journal article; Peer reviewed, 2022)Purpose Ankle fractures are commonly occurring fractures, especially in the aging population, where they often present as fragility fractures. The disease burden and economic costs to the patient and society are considerable. ... -
Answer to comment on "sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study"
(Journal article, 2013-07-01)We discuss the comments on our article “Sleep quality, arousal and pain thresholds in migraineurs. A blinded controlled polysomnographic study” published in JHP 2013 Feb 14;14(1):12. We hypothesize that migraineurs need ... -
Anterior cingulate gamma-aminobutyric acid concentrations and electroconvulsive therapy
(Journal article; Peer reviewed, 2020-09-17)Objective The anticonvulsant hypothesis posits that ECT’s mechanism of action is related to enhancement of endogenous anticonvulsant brain mechanisms. Results of prior studies investigating the role of the inhibitory ... -
Anterior cruciate ligament—return to sport after injury scale: validation of the Norwegian language version
(Journal article; Peer reviewed, 2020)Purpose: Evidence is emerging on the importance of psychological readiness to return to sport after anterior cruciate ligament (ACL) reconstruction. The ACL-Return to Sport after Injury scale (ACL-RSI) is developed to ... -
Anti-depressive effectiveness of olanzapine, quetiapine, risperidone and ziprasidone: a pragmatic, randomized trial
(Peer reviewed; Journal article, 2011-08-31)Background: Efficacy studies indicate anti-depressive effects of at least some second generation antipsychotics (SGAs). The Bergen Psychosis Project (BPP) is a 24-month, pragmatic, industry-independent, randomized, head-tohead ...