• Disease-Course Adapting Machine Learning Prognostication Models in Elderly Patients Critically Ill With COVID-19: Multicenter Cohort Study With External Validation 

  Jung, Christian; Mamandipoor, Behrooz; Fjølner, Jesper; Bruno, Raphael Romano; Wernly, Bernhard; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Wolff, Georg; Kelm, Malte; Beil, Michael; Sviri, Sigal; van Heerden, Peter V.; Szczeklik, Wojciech; Czuczwar, Miroslaw; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Cecconi, Maurizio; Leaver, Susannah; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans Kristian; Osmani, Venet (Journal article; Peer reviewed, 2022)

  Background:The COVID-19 pandemic caused by SARS-CoV-2 is challenging health care systems globally. The disease disproportionately affects the elderly population, both in terms of disease severity and mortality risk. ...

• Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy 

  Nielsen, Hans Jørgen; Nedrebø, Bjørn Gunnar; Fosså, Alexander; Andersen, John Roger; Assmus, Jörg; Dagsland, Vigdis Halvorsen; Dankel, Simon N; Gudbrandsen, Oddrun Anita; Fernø, Johan; Hjellestad, Iren Drange; Hjermstad, Marianne Jensen; Kolotkin, Ronette Loganzo; Thorsen, Håvard Luong; Mellgren, Gunnar; Flølo, Tone Nygaard (Journal article; Peer reviewed, 2022)

  Background/objectives There is limited long-term data comparing the outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, both with respect to body weight, quality of life (QOL) and ...

• Acidification of the Nordic Seas 

  Fransner, Sara Filippa Krusmynta; Fröb, Friederike; Tjiputra, Jerry; Goris, Nadine; Lauvset, Siv Kari; Skjelvan, Ingunn; Jeansson, Emil; Omar, Abdirahman; Chierici, Melissa; Jones, Elizabeth Marie; Fransson, Agneta; Ólafsdóttir, Sólveig R.; Johannessen, Truls; Olsen, Are (Journal article; Peer reviewed, 2022)

  Due to low calcium carbonate saturation states, and winter mixing that brings anthropogenic carbon to the deep ocean, the Nordic Seas and their cold-water corals are vulnerable to ocean acidification. Here, we present a ...

• Anti-PD-L1/TGF-βR fusion protein (SHR-1701) overcomes disrupted lymphocyte recovery-induced resistance to PD-1/PD-L1 inhibitors in lung cancer 

  Cheng, Bo; Ding, Kaikai; Chen, Pengxiang; Ji, Jianxiong; Luo, Tao; Guo, Xiaofan; Qiu, Wei; Ma, Chunhong; Meng, Xue; Wang, Jian; Yu, Jinming; Liu, Yuan (Journal article, 2022)

  Background Second-generation programmed cell death-protein 1/programmed death-ligand 1 (PD-1/PD-L1) inhibitors, such as bintrafusp alfa (M7824), SHR-1701, and YM101, have been developed to simultaneously block PD-1/PD-L1 ...

• The effect of gadolinium-based contrast-agents on automated brain atrophy measurements by FreeSurfer in patients with multiple sclerosis 

  Lie, Ingrid Anne; Kerklingh, Emma; Wesnes, Kristin; van Nederpelt, David R.; Brouwer, Iman; Torkildsen, Øivind; Myhr, Kjell-Morten; Barkhof, Frederik; Bø, Lars; Vrenken, Hugo (Journal article; Peer reviewed, 2022)

  Objective To determine whether reliable brain atrophy measures can be obtained from post-contrast 3D T1-weighted images in patients with multiple sclerosis (MS) using FreeSurfer. Methods Twenty-two patients with MS ...

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