• Kaplan-Meier and Cox Regression Are Preferable for the Analysis of Time to Revision of Joint Arthroplasty: Thirty-One Years of Follow-up for Cemented and Uncemented THAs Inserted from 1987 to 2000 in the Norwegian Arthroplasty Register 

  Lie, Stein Atle; Fenstad, Anne Marie; Lygre, Stein Håkon Låstad; Kroken, Gard; Dybvik, Eva Hansen; Gjertsen, Jan-Erik; Hallan, Geir; Dale, Håvard; Furnes, Ove Nord (Journal article; Peer reviewed, 2022)

  Background: Previous studies have suggested that the probability function of 1 minus the Kaplan-Meier survivorship overestimates revision rates of implants and that patient death should be included in estimates as a competing ...

• LRFN5 locus structure is associated with autism and influenced by the sex of the individual and locus conversions 

  Lybæk, Helle; Robson, Michael; de Leeuw, Nicole; Hehir-Kwa, Jayne Y.; Jeffries, Aaron; Haukanes, Bjørn Ivar; Berland, Siren; de Bruijn, Diederik; Mundlos, Stefan; Spielmann, Malte; Houge, Gunnar Douzgos (Journal article; Peer reviewed, 2022)

  LRFN5 is a regulator of synaptic development and the only gene in a 5.4 Mb mammalian-specific conserved topologically associating domain (TAD); the LRFN5 locus. An association between locus structural changes and developmental ...

• MicroRNA-138 abates fibroblast motility with effect on invasion of adjacent cancer cells 

  Rajthala, Saroj; Parajuli, Himalaya; Dongre, Harsh Nitin; Ljøkjel, Borghild; Hoven, Kristin Marie; Kvalheim, Arild; Lybak, Stein; Neppelberg, Evelyn; Sapkota, Dipak; Johannessen, Anne Christine; Costea, Daniela Elena (Journal article; Peer reviewed, 2022-03-17)

  Background: Recent studies have shown aberrant expression of micro-RNAs in cancer-associated fibroblasts (CAFs). This study aimed to investigate miR-138 dysregulation in CAFs in oral squamous cell carcinoma (OSCC) and its ...

• Buegangsdehiscens 

  Goplen, Frederik Kragerud; Hess-Erga, Jeanette; Opheim, Leif Runar; Silvola, Juha Tapio; Stene, Brit Kari; Törpel, Jörg; Uppheim, Alexander; Bunne, Bodil Iris Marie (Journal article; Peer reviewed, 2022)

  Buegangsdehiscens er en tilstand med plagsomme øresymptomer og svimmelhet forårsaket av en defekt i benet mellom det indre øret og midtre skallegrop. Sykdommen er ufarlig, og for mange pasienter er det tilstrekkelig med ...

• Understanding proteostasis dysregulation in phenylketonuria – a paradigm disease for inborn error of metabolism 

  Prestegård, Karina Skjervheim (Doctoral thesis, 2022-09-06)

  Fenylketonuria (PKU) er en medfødt stoffskiftesykdom forårsaket av mutasjoner i genet for fenylalanin hydroksylase (PAH), og fører til ustabile og ofte feilfoldete enzymer med nedsatt evne til å metabolisere aminosyren ...

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