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Stable Southern Hemisphere westerly winds throughout the Holocene until intensification in the last two millennia (Journal article; Peer reviewed, 2022)The Southern Hemisphere westerly winds sustain the Southern Ocean’s role as one of Earth’s main carbon sinks, and have helped sequester nearly half the anthropogenic CO2 stored in the ocean. Observations show shifts in the ...
Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes (Journal article; Peer reviewed, 2022-05-05)Persons with type 2 diabetes born in the regions of famine exposures have disproportionally elevated risk of vision-threatening proliferative diabetic retinopathy (PDR) in adulthood. However, the underlying mechanisms are ...
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence (Journal article; Peer reviewed, 2022)We investigated genomic and transcriptomic changes in paired tumor samples of 29 in-house multiple myeloma (MM) patients and 28 patients from the MMRF CoMMpass study before and after treatment. A change in clonal composition ...
Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function (Journal article; Peer reviewed, 2022)Objective: Neonatal lupus erythematosus (NLE) may develop after transplacental transfer of maternal autoantibodies with cardiac manifestations (congenital heart block, CHB) including atrioventricular block, atrial and ...
The value of histological examination in the diagnosis of tuberculous lymphadenitis in the era of rapid molecular diagnosis (Journal article; Peer reviewed, 2022)Extrapulmonary tuberculosis often poses a diagnostic challenge. This study aimed to assess the value of histological examination in diagnosing tuberculous lymphadenitis (LNTB) when performed simultaneously with rapid ...