Blar i Department of Clinical Science på tittel
Viser treff 696-715 av 2426
-
Electromembrane extraction of methotrexate and its metabolites
(Master thesis, 2021-05-20)Within pharmaceutical analysis, sample preparation is essential to make a sample compatible with the chosen analytical instrument, prevent contamination and damage of the instrument, and to avoid interference from matrix ... -
Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
(Peer reviewed; Journal article, 2018)Ankyrin-3 (ANK3) is one of the few genes that have been consistently identified as associated with bipolar disorder by multiple genome-wide association studies. However, the exact molecular basis of the association remains ... -
Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement
(Journal article; Peer reviewed, 2021)Background A high proportion of COVID‐19 patients have cardiac involvement, even those without known cardiac disease. Downregulation of angiotensin converting enzyme 2 (ACE2), a receptor for SARS‐CoV‐2 and the renin‐angiotensin ... -
Elevated plasma cystathionine is associated with increased risk of mortality among patients with suspected or established coronary heart disease
(Journal article; Peer reviewed, 2019)Background Elevated circulating cystathionine levels are related to atherosclerotic cardiovascular disease, a leading cause of death globally. Objective We investigated whether plasma cystathionine was associated with ... -
ELISA-basert deteksjon av biomarkørar i serumprøver ved Giardia-indusert kronisk utmattingssyndrom og funksjonelle gastrointestinale lidingar - Nivå av B-cell activating factor og antistoff mot cytolethal distending toxin B og flagellin hjå personar med langvarige plager etter Giardia-utbrotet i Bergen
(Master thesis, 2017-06-08)Bakgrunn: Parasitten Giardia lamblia forureina drikkevasskjelda Svartediket i Bergen hausten 2004, og var årsaka til eit stort utbrot av giardiasis i menneske. Denne gastrointestinale infeksjonen blei for mange starten på ... -
Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307
(Peer reviewed; Journal article, 2019)Objectives: Recent reports indicate the emergence of a new carbapenemase-producing Klebsiella pneumoniae clone, ST307. We sought to better understand the global epidemiology and evolution of this clone and evaluate its ... -
Emergence of a Streptococcus dysgalactiae subspecies equisimilis stG62647-lineage associated with severe clinical manifestations
(Peer reviewed; Journal article, 2017-08-08)Increasing incidence rates of invasive Streptococcus dysgalactiae subspecies equisimilis (SDSE) infections have been reported worldwide, but the evolutionary mechanisms underlying this development remain elusive. Through ... -
The emerging role of cd24 in cancer theranostics—a novel target for fluorescence image-guided surgery in ovarian cancer and beyond
(Journal article; Peer reviewed, 2020)Complete cytoreductive surgery is the cornerstone of the treatment of epithelial ovarian cancer (EOC). The application of fluorescence image-guided surgery (FIGS) allows for the increased intraoperative visualization and ... -
emm gene diversity, superantigen gene profiles and presence of SlaA among clinical isolates of group A, C and G streptococci from western Norway
(Peer reviewed; Journal article, 2010-11-20)In order to investigate molecular characteristics of beta-hemolytic streptococcal isolates from western Norway, we analysed the entire emm gene sequences, obtained superantigen gene profiles and determined the prevalence ... -
Emphysema and airway wall thickness assessed by quantitative computed tomography - relation to respiratory symptoms and lung function
(Doctoral thesis, 2011-11-28)Aims: 1 – To quantify emphysema (%LAA, percentage Low Attenuation Areas) and airway wall thickness (AWT-Pi10, Airway Wall Thickness in a standardized airway with an internal perimeter of 10 mm) in ever-smoking COPD and ... -
En undersøkelse av brentkalks effekt på frittlevende stadier av lakselus, og om virkningen har en sammenheng med partikkelstørrelse og reaktivitet, T60
(Master thesis, 2018-08-31)I Norge gir lakselusen ( Lepeophtheirus salmonis) alene tap på flere hundre millioner kroner hvert år for lakseoppdretterne på grunn av dødelighet, tap av tilvekst, samt nedgradering av kvalitet og utgifter til behandling ... -
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling
(Journal article; Peer reviewed, 2020)Cell replacement therapies hold great therapeutic potential. Nevertheless, our knowledge of the mechanisms governing the developmental processes is limited, impeding the quality of differentiation protocols. Generating ... -
Endocan in Acute Leukemia: Current Knowledge and Future Perspectives
(Journal article; Peer reviewed, 2022)Endocan is a soluble dermatan sulfate proteoglycan expressed by endothelial cells and detected in serum/plasma. Its expression is increased in tumors/tumor vessels in several human malignancies, and high expression (high ... -
Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition: an ESE clinical practice guideline
(Journal article; Peer reviewed, 2022)Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment but are associated with significant autoimmune endocrinopathies that pose both diagnostic and treatment challenges. The aim of this guideline is to ... -
The endogenous hallucinogen and trace amine N,N-dimethyltryptamine (DMT) displays potent protective effects against hypoxia via sigma-1 receptor activation in human primary iPSC-derived cortical neurons and microglia-like immune cells
(Peer reviewed; Journal article, 2016)N,N-dimethyltryptamine (DMT) is a potent endogenous hallucinogen present in the brain of humans and other mammals. Despite extensive research, its physiological role remains largely unknown. Recently, DMT has been found ... -
Endometrial ablation; less is more? Historical cohort study comparing long-term outcomes from two time periods and two treatment modalities for 854 women
(Peer reviewed; Journal article, 2019-07-10)Background: Abnormal uterine bleeding needs surgical treatment if medical therapy fails. After introduction of non-hysteroscopic endometrial ablation as alternative to hysteroscopic endometrial resection, we aimed to compare ... -
Endometrial carcinoma: a step closer to individualized therapy? Exploring transcriptional alterations in relation to prognostic biomarkers
(Doctoral thesis, 2013-09-30)Background: Endometrial cancer is diagnosed early and has in general a good prognosis. The more important it is to diagnose and treat the poor-prognosis cases. Therapy of endometrial carcinoma patients per today is to a ... -
Endoplasmic Reticulum Calcium Pumps and Tumor Cell Differentiation
(Journal article; Peer reviewed, 2020)Endoplasmic reticulum (ER) calcium homeostasis plays an essential role in cellular calcium signaling, intra-ER protein chaperoning and maturation, as well as in the interaction of the ER with other organelles. Calcium is ... -
Endothelial dysfunction in ME/CFS patients
(Journal article; Peer reviewed, 2023-02-02)Objective: A few earlier studies have found impaired endothelial function in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The present study investigated large-vessel and small-vessel endothelial ... -
Endovascular treatment in the elderly
(Doctoral thesis, 2024-09-13)Bakgrunn Nevrologiske lidelser utgjør en stor helsemessig utfordring og hjerneslag er globalt sett den nest hyppigste årsaken til død og den fremste årsaken til uførhet. Iskemisk hjerneslag behandles primært med medisinsk ...