Browsing Department of Clinical Science by Title
Now showing items 2214-2233 of 2317
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Trends in maternal use of snus and smoking tobacco in pregnancy. A register study in southern Norway
(Peer reviewed; Journal article, 2019-12-16)Background: The use of tobacco products including Swedish snus (moist snuff) in pregnancy may cause adverse health outcomes. While smoking prevalence has decreased among fertile women in Norway, snus use has increased ... -
Trends in the occurrence of ischaemic heart disease over time in rheumatoid arthritis: 1821 patients from 1972 to 2017
(Journal article; Peer reviewed, 2022)Objective To evaluate trends of acute myocardial infarction (AMI) and ischaemic heart disease (IHD) in rheumatoid arthritis (RA) patients compared with the general population over time. Method We performed a retrospective ... -
Trimethyllysine predicts all-cause and cardiovascular mortality in community-dwelling adults and patients with coronary heart disease
(Journal article; Peer reviewed, 2021)Aims Trimethyllysine (TML) is involved in carnitine synthesis, serves as a precursor of trimethylamine N-oxide (TMAO) and is associated with cardiovascular events in patients with established coronary heart disease (CHD). ... -
Truncating and zinc-finger variants in GLI2 are associated with hypopituitarism
(Journal article; Peer reviewed, 2022)Variants in transcription factor GLI2 have been associated with hypopituitarism and structural brain abnormalities, occasionally including holoprosencephaly (HPE). Substantial phenotypic variability and nonpenetrance have ... -
The Truth behind the Zeros: A New Approach to Principal Component Analysis of the Neuropsychiatric Inventory
(Journal article; Peer reviewed, 2021)Psychiatric syndromes in dementia are often derived from the Neuropsychiatric Inventory (NPI) using principal component analysis (PCA). The validity of this statistical approach can be questioned, since the excessive ... -
Tryptophan catabolites as metabolic markers of vitamin B-6 status evaluated in cohorts of healthy adults and cardiovascular patients
(Journal article; Peer reviewed, 2020)Background Vitamin B-6 status is routinely measured as pyridoxal 5′-phosphate (PLP) in plasma. Low concentrations of PLP are associated with rheumatic, cardiovascular, and neoplastic diseases. We have previously shown ... -
The tuberculin skin test in school going adolescents in South India: associations of socio-demographic and clinical characteristics with TST positivity and non-response
(Peer reviewed; Journal article, 2014-11-18)Background. India has generally used 1 TU purified protein derivative (PPD) as opposed to 2 TU PPD globally, limiting comparisons. It is important to assess latent TB infection in adolescents given that they may be a target ... -
The tuberculin skin test in school going adolescents in South India: associations of socio-demographic and clinical characteristics with TST positivity and non-response
(Peer reviewed; Journal article, 2014-11-18)Background: India has generally used 1 TU purified protein derivative (PPD) as opposed to 2 TU PPD globally, limiting comparisons. It is important to assess latent TB infection in adolescents given that they may be a target ... -
Tuberculosis-Associated Hemophagocytic Lymphohistiocytosis: A Review of Current Literature
(Journal article; Peer reviewed, 2023)Hemophagocytic lymphohistiocytosis (HLH) is a condition of immune dysregulation and hyperinflammation, leading to organ failure and death. Malignancy, autoimmune conditions, and infections, including Mycobacterium tuberculosis ... -
Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets
(Journal article; Peer reviewed, 2022-08-03)Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D). Nevertheless, circadian ... -
Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
(Journal article; Peer reviewed, 2023)Objectives: To systematically review the literature for assay methods that aim to evaluate type I interferon (IFN-I) pathway activation and to harmonise-related terminology. Methods: Three databases were searched for ... -
Tyrosine kinase inhibitors and interferon‐α increase tunneling nanotube (TNT) formation and cell adhesion in chronic myeloid leukemia (CML) cell lines (
(Journal article; Peer reviewed, 2020)Chronic myeloid leukemia (CML) is a stem cell disease of the bone marrow where mechanisms of inter‐leukemic communication and cell‐to‐cell interactions are proposed to be important for optimal therapy response. Tunneling ... -
UGT1A4 og UGT2B15 enkeltnukleotidpolymorfismer. Etablering av real time PCR metoder og betydning for tamoxifen metabolisme
(Master thesis, 2008-06-02)Brystkreft er den vanligste kreftformen blant kvinner i Norge og adjuvant tamoxifenbehandling er vist å øke tilbakefallsfri og total overlevelse. Den interinidividuelle varaiasjonen i effekt og bivirkninger av tamoxifen ... -
Ultraprosessert mat burde være et kostråd: JA
(Journal article, 2023) -
Ultrasonography of major salivary glands in primary and juvenile Sjögren’s syndrome
(Doctoral thesis, 2019-06-07)Background: Primary Sjögrens’s syndrome (pSS) is a systemic autoimmune disease, mainly affecting the salivary and lacrimal glands. Primary SS can also affect the younger population and when it does, the denomination is ... -
Ultrasound in Crohn’s Disease - bowel wall characteristics and perfusion estimates using microbubbles
(Doctoral thesis, 2013-01-18)Crohn’s disease (CD) is a chronic inflammatory bowel disease which often presents early in life and sometimes can be debilitating. The patients need frequent diagnostic work-up to assess disease activity, location, extent ... -
Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells
(Journal article; Peer reviewed, 2020)Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death worldwide. Poor drug delivery to tumours is thought to limit chemotherapeutic treatment efficacy. Sonoporation combines ultrasound (US) and microbubbles ... -
Ultraviolet radiation as a predictor of sex hormone levels in postmenopausal women: A European multi-center study (ECRHS)
(Journal article; Peer reviewed, 2021)Background Solar ultraviolet radiation (UVR) affects the body through pathways that exhibit positive as well as negative health effects such as immunoregulation and vitamin D production. Different vitamin D metabolites ... -
Understanding fatigue in Sjögren’s Syndrome: Outcome measures, biomarkers and possible interventions
(Journal article; Peer reviewed, 2021)Sjögren’s syndrome (SS) is an autoimmune disease affecting the salivary and lacrimal glands. Symptoms range from dryness to severe extra-glandular disease involving manifestations in the skin, lungs, nervous system, and ... -
Understanding the Effects of Antipsychotics on Appetite Control
(Journal article; Peer reviewed, 2021)Antipsychotic drugs (APDs) represent a cornerstone in the treatment of schizophrenia and other psychoses. The effectiveness of the first generation (typical) APDs are hampered by so-called extrapyramidal side effects, and ...