Browsing Department of Clinical Science by Title

Now showing items 2223-2242 of 2375

    • Thrombectomy in large vessel occlusion stroke—Does age matter? 

      Rezai Kallaj, Mehdi; Dalen, Ingvild; Advani, Rajiv; Fjetland, Lars; Kurz, Kathinka Dæhli; Sandve, Knut Olav Lende; Kurz, Friedrich Martin Wilhelm (Journal article; Peer reviewed, 2022)
      Objectives Endovascular treatment (EVT) is the gold standard treatment for emergent large vessel occlusion (LVO). The benefit of EVT for emergent LVO in elderly patients (>80 years old) is still debated as they have been ...

    • Thrombocytopaenia in the critically ill 

      Bruserud, Øyvind; Mosevoll, Knut Anders; Kristoffersen, Einar Klæboe; Kvåle, Reidar; Reikvam, Håkon (Journal article; Peer reviewed, 2021)

    • Thrombosis and thrombocytopenia after HPV vaccination 

      Johansen, Silje; Lægreid, Ingvild Jenssen; Ernstsen, Siw Leiknes; Azrakhsh, Nessar Ahmad; Kittang, Astrid Marta Olsnes; Lindås, Roald; Gjertsen, Bjørn Tore; Vetti, Nils; Mørtberg, Trude Victoria; Sørvoll, Ingvild Hausberg; Holme, Pål Andre; Ahlen, Maria Therese; Reikvam, Håkon (Journal article; Peer reviewed, 2021)
      Background Vaccine-induced immune thrombotic thrombocytopenia (VITT) has so far only been reported after adenovirus vector severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines. Objective We report ...

    • Thrombus characteristics evaluated by acute optical coherence tomography in ST elevation myocardial Infarction 

      Eriksen, Erlend; Herstad, Jon; Pertiwi, Kartika Ratna; Tuseth, Vegard; Nordrehaug, Jan Erik; Bleie, Øyvind; van der Wal, Allard C. (Journal article; Peer reviewed, 2022)
      Aims ST elevation myocardial infarction (STEMI) is caused by an occlusive thrombosis of a coronary artery. We wanted to assess if the thrombus can be characterized according to erythrocyte content and age using intravascular ...

    • Thymoquinone Potentially Modulates the Expression of Key Onco- and Tumor Suppressor miRNAs in Prostate and Colon Cancer Cell Lines: Insights from PC3 and HCT-15 Cells 

      Osorio-Pérez, Sofía Madeline; Estrada-Meza, Carolina; Ruiz-Manriquez, Luis M.; Arvizu-Espinosa, María Goretti; Srivastava, Aashish; Sharma, Ashutosh; Paul, Sujay (Journal article; Peer reviewed, 2023)
      Prostate cancer (PC) and colon cancer significantly contribute to global cancer-related morbidity and mortality. Thymoquinone (TQ), a naturally occurring phytochemical found in black cumin, has shown potential as an ...

    • Tick-borne infections in Sogn og Fjordane, western Norway. Seroprevalence, risk factors and subjective health complaints in blood donors 

      Hjetland, Reidar (Doctoral thesis, 2017-09-15)
      Background: The tick Ixodes ricinus is involved in the transmission of a large variety of pathogens of medical and veterinary importance in Norway. The most prevalent human tickborne disease in the country is Lyme borreliosis, ...

    • Tidal breathing parameters in extremely premature infants. Feasibility and clinical utility of electromagnetic inductance plethysmography 

      Bentsen, Mariann Haavik Lysfjord (Doctoral thesis, 2018-09-06)
      Background: Extremely preterm (EP) birth is associated with adverse lung growth, due to disturbance of programmed and fine-tuned sequences of normal intrauterine development, as well as the trauma inflicted by life-saving ...

    • Tidal Expiratory Flow Limitation. A new method for evaluating pulmonary function in elderly and patients with Chronic Obstructive Pulmonary Disease 

      Aarli, Bernt Bøgvald (Doctoral thesis, 2018-01-18)
      Background: Lung function declines with old age and is further accelerated by exposure to noxious particles. As our society ages, expected lifespan increases, and prevalence of chronic obstructive pulmonary disease (COPD) ...

    • Tidal volumes and pressures delivered by the NeoPuff T-piece resuscitator during resuscitation of term newborns 

      Bjorland, Peder Aleksander; Ersdal, Hege Langli; Haynes, Joanna Clare; Ushakova, Anastasia; Øymar, Knut Asbjørn Alexander; Rettedal, Siren (Journal article; Peer reviewed, 2022)
      Aim: T-piece resuscitators are commonly used for respiratory support during newborn resuscitation. This study aimed to describe delivered pressures and tidal volumes when resuscitating term newborns immediately after birth, ...

    • Tidal volumes and pressures delivered by the NeoPuff T-piece resuscitator during resuscitation of term newborns 

      Bjorland, Peder Aleksander; Ersdal, Hege Langli; Haynes, Joanna Clare; Ushakova, Anastasia; Øymar, Knut Asbjørn Alexander; Rettedal, Siren (Journal article; Peer reviewed, 2022)
      Aim: T-piece resuscitators are commonly used for respiratory support during newborn resuscitation. This study aimed to describe delivered pressures and tidal volumes when resuscitating term newborns immediately after birth, ...

    • Tigecycline attenuates polymorphonuclear leukocyte (PMN) receptors but not functions 

      Næss, Are; Andreeva, Hristina D.; Sørnes, Steinar (Peer reviewed; Journal article, 2011)
      Tigecycline achieves high intracellular concentrations in polymorphonuclear leukocytes (PMNs). To evaluate the effects of tigecycline on human PMNs, PMNs were incubated with tigecycline dilutions (0.1 to 100 mg L–¹). ...

    • Time-Resolved Concentrations of Serum Amino Acids, One-carbon Metabolites, and B-vitamin Biomarkers during the Postprandial and Fasting State: The Postprandial Metabolism in Healthy Young Adults (PoMet) study 

      Anfinsen, Åslaug Matre; Johannesen, Christina Osland; Myklebust, Vilde H.; Rosendahl-Riise, Hanne; McCann, Adrian; Nygård, Ottar Kjell; Dierkes, Jutta; Lysne, Vegard (Journal article; Peer reviewed, 2023)
      Metabolomics has been utilised in epidemiological studies to investigate biomarkers of nutritional status and metabolism in relation to non-communicable diseases. However, little is known about the effect of prandial status ...

    • Timing of menarche in Norwegian girls: Associations with body mass index, waist circumference and skinfold thickness 

      Bratke, Heiko; Bruserud, Ingvild Særvold; Brannsether-Ellingsen, Bente; Assmus, Jörg; Bjerknes, Robert; Roelants, Mathieu; Juliusson, Petur Benedikt (Peer reviewed; Journal article, 2017-06-06)
      Background: Research studies show conflicting results regarding the association between menarche and body weight. The purpose of the present study was to investigate if anthropometric indicators of body composition, body ...

    • Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer 

      Berg, Anna; Fasmer, Kristine Eldevik; Mauland, Karen Klepsland; Ytre-Hauge, Sigmund; Høivik, Erling Andre; Husby, Jenny Hild Aase; Tangen, Ingvild Løberg; Trovik, Jone; Halle, Mari Kyllesø; Woie, Kathrine; Bjørge, Line; Bjørnerud, Atle; Salvesen, Helga; Werner, Henrica Maria Johanna; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2016-09-13)
      Hypoxia is frequent in solid tumors and linked to aggressive phenotypes and therapy resistance. We explored expression patterns of the proposed hypoxia marker HIF-1α in endometrial cancer (EC) and investigate whether ...

    • Tissue characterisation by ultrasound strain imaging. Methodological aspects and gastroenterological applications 

      Havre, Roald Flesland (Doctoral thesis, 2012-10-11)
      Real-Time Elastography (RTE) is a new imaging modality that monitors tissue strain during applied stress. The aim of this thesis was to validate if RTE was a reliable modality to reflect pathologically induced differences ...

    • Tissue Glucocorticoid Metabolism in Adrenal Insufficiency: A Prospective Study of Dual-release Hydrocortisone Therapy 

      Dineen, Rosemary A.; Martin-Grace, Julie; Ahmed, Khalid Mohamed Saeed; Taylor, Angela E.; Shaheen, Fozia; Schiffer, Lina; Gilligan, Lorna C.; Lavery, Gareth G.; Frizelle, Isolda; Gunness, Anjuli; Garrahy, Aoife; Hannon, Anne Marie; Methlie, Paal; Husebye, Eystein Sverre; Stewart, Paul M.; Tomlinson, Jeremy W.; Hawley, James M.; Keevil, Brian G.; O'Reilly, Michael W.; Smith, Diarmuid; McDermott, John; Healy, Marie-Louise; Agha, Amar; Pazderska, Agnieszka; Gibney, James; Behan, Lucy-Ann; Thompson, Chris J.; Arlt, Wiebke; Sherlock, Mark (Journal article; Peer reviewed, 2023)
      Background Patients with adrenal insufficiency (AI) require life-long glucocorticoid (GC) replacement therapy. Within tissues, cortisol (F) availability is under the control of the isozymes of 11β-hydroxysteroid ...

    • Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants 

      Tran, Trung The; Vaage, Eline Benno; Mehta, Adi; Chopra, Adity; Tietze, Lisa; Kolderup, Anette; Anthi, Aina Karen; König, Marton; Nygaard, Gro Owren; Lind, Andreas; Müller, Fredrik; Nissen-Meyer, Lise Sofie Haug; Magnus, Per Minor; Trogstad, Lill; Mjaaland, Siri; Søraas, Arne Vasli; Midtvedt, Karsten; Åsberg, Anders; Barratt-Due, Andreas; Medhus, Asle Wilhelm; Høivik, Marte Lie; Lundin, Knut; Karlsen, Randi Fuglaas; Dahle, Reidun; Danielsson, Karin; Thomassen, Kristine Stien; Kro, Grete Anette Birkeland; Cox, Rebecca Jane; Zhou, Fan; Langeland, Nina; Aukrust, Pål; Melum, Espen; Åvitsland, Tone Lise; Wiencke, Kristine; Holter, Jan Cato; Munthe, Ludvig Andre; Grødeland, Gunnveig; Andersen, Jan Terje; Vaage, John T.; Lund-Johansen, Fridtjof (Journal article; Peer reviewed, 2022)
      Diagnostic assays currently used to monitor the efficacy of COVID-19 vaccines measure levels of antibodies to the receptor-binding domain of ancestral SARS-CoV-2 (RBDwt). However, the predictive value for protection against ...

    • Titrating complex mass cytometry panels 

      Gullaksen, Stein-Erik; Bader, Lucius; Hellesøy, Monica; Sulen, Andre; Fagerholt, Oda Helen Eck; Engen, Caroline Benedicte Nitter; Skavland, Jørn; Gjertsen, Bjørn Tore; Gavasso, Sonia (Peer reviewed; Journal article, 2019-07-13)
      We describe here a simple and efficient antibody titration approach for cell‐surface markers and intracellular cell signaling targets for mass cytometry. The iterative approach builds upon a well‐characterized backbone ...

    • TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies 

      Gierman, Lobke; Silva, Gabriela; Pervaiz, Zahra; Rakner, Johanne Johnsen; Mundal, Siv Boon; Thaning, Astrid J.; Nervik, Ingunn; Elschot, Mattijs; Mathew, Seema; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2020)
      Inflammation and oxidative stress at the maternal‐fetal interface characterize the placental dysfunction that underlies the pregnancy disorder preeclampsia. Specialized fetal trophoblasts directly interact with leukocytes ...

    • TNF-α is associated with loss of lean body mass only in already cachectic COPD patients 

      Eagan, Tomas Mikal; Gabazza, Esteban C.; D’Alessandro-Gabazza, Corina; Gil-Bernabe, Paloma; Aoki, Shinya; Hardie, Jon Andrew; Bakke, Per; Wagner, Peter D. (Peer reviewed; Journal article, 2012-06-18)