Blar i Department of Clinical Science på tittel

Viser treff 2005-2024 av 2316

    • Serum or Plasma for Quantification of Direct Oral Anticoagulants? 

      Aakerøy, Rachel; Stokes, Charlotte Lorentze; Tomic, Marija; Hegstad, Solfrid; Kristoffersen, Ann-Helen; Ellekjær, Hanne; Schjøtt, Jan Didrik; Spigset, Olav; Helland, Arne (Journal article; Peer reviewed, 2022)
      Background: Direct oral anticoagulants are increasingly replacing vitamin K antagonists for prevention of stroke in patients with atrial fibrillation, partly owing to the lack of a need for routine monitoring. Therapeutic ...

    • Serumkonsentrasjonsmåling av gentamicin hos barn 

      Grodås, Karolina Teresa Maulen; Døllner, Henrik; Thaulow, Christian Magnus; Knudsen, Per Kristian; Tønnessen, Anders; Skeibrok, Mari; Klingenberg, Claus Andreas (Journal article; Peer reviewed, 2023)
      BAKGRUNN Gentamicin brukes ofte ved alvorlige infeksjoner hos barn. Det har vært rutine i Norge å måle serumkonsentrasjon av gentamicin rett før andre eller tredje dose (0-prøve) for å vurdere risiko for toksisitet. Den ...

    • Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy 

      Nielsen, Hans Jørgen; Nedrebø, Bjørn Gunnar; Fosså, Alexander; Andersen, John Roger; Assmus, Jörg; Dagsland, Vigdis Halvorsen; Dankel, Simon N; Gudbrandsen, Oddrun Anita; Fernø, Johan; Hjellestad, Iren Drange; Hjermstad, Marianne Jensen; Kolotkin, Ronette Loganzo; Thorsen, Håvard Luong; Mellgren, Gunnar; Flølo, Tone Nygaard (Journal article; Peer reviewed, 2022)
      Background/objectives There is limited long-term data comparing the outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, both with respect to body weight, quality of life (QOL) and ...

    • Severe asthma trajectories in adults: findings from the NORDSTAR cohort 

      von Bülow, Anna; Hansen, Susanne; Sandin, Patrik; Ernstsson, Olivia; Janson, Christer; Lehtimäki, Lauri; Kankaanranta, Hannu; Ulrik, Charlotte; Aarli, Bernt Bøgvald; Geale, Kirk; Tang, Sheila Tuyet; Wolf, Maija; Backer, Vibeke; Hilberg, Ole; Altraja, Alan; Backman, Helena; Ludviksdottir, Dora; Björnsdottir, Unnur Steina; Kauppi, Paula; Sandström, Thomas; Sverrild, Asger; Yasinska, Valentyna; Kilpeläinen, Maritta; Dahlen, Barbro; Viinanen, Arja; Bjermer, Leif; Bossios, Apostolos; Porsbjerg, Celeste (Journal article; Peer reviewed, 2023)
      Background There is limited evidence on the pathways leading to severe asthma and we are presently unable to effectively predict the progression of the disease. We aimed to describe the longitudinal trajectories leading ...

    • Severe exercise-induced laryngeal obstruction treated with supraglottoplasty 

      Sandnes, Astrid; Hilland, Magnus; Vollsæter, Maria; Andersen, Tiina Maarit; Engesæter, Ingvild Øvstebø; Sandvik, Lorentz; Heimdal, John-Helge; Halvorsen, Thomas; Eide, Geir Egil; Røksund, Ola Drange; Clemm, Hege Synnøve Havstad (Peer reviewed; Journal article, 2019-07-31)
      Introduction: Exercise induced laryngeal obstruction (EILO) is relatively common in adolescents, with symptoms often confused with exercise induced asthma. EILO often starts with medial or inward rotation of supraglottic ...

    • Severe headache in primary Sjögren's syndrome treated with intrathecal rituximab 

      Tjensvoll, Anne Bolette; Lauvsnes, Maria Boge; Norheim, Katrine Brække; Omdal, Roald (Peer reviewed; Journal article, 2019-01-17)
      A severe and persistent migrainous headache in a patient with primary Sjøgren's syndrome unresponsive to treatment with immunosuppressive drugs, triptans, opioids, and NSAIDs, responded successfully to intrathecal B‐cell ...

    • Sex differences in arterial hypertension 

      Gerdts, Eva; Sudano, Isabella; Brouwers, Sofie; Borghi, Claudio; Bruno, RM; Ceconi, Claudio; Cornelissen, Veronique; Dievart, Francois; Ferrini, Marc; Kahan, Thomas; Løchen, Maja-Lisa; Maas, Angela H.E.M.; Mahfoud, Felix; Mihailidou, Anastasia Susie; Moholdt, Trine; Parati, Gianfranco; de Simone, Giovanni (Journal article; Peer reviewed, 2022)
      There is strong evidence that sex chromosomes and sex hormones influence blood pressure (BP) regulation, distribution of cardiovascular (CV) risk factors and co-morbidities differentially in females and males with essential ...

    • Sex differences in blood pressure in midlife: associations with risk factors and acute coronary syndromes in the Hordaland Health Studies 

      Kringeland, Ester Anne (Doctoral thesis, 2022-12-06)
      Bakgrunn: Blant unge voksne har friske kvinner vanligvis lavere blodtrykk (BT) enn menn. Men allerede fra 20-årene har kvinner en brattere stigning i BT enn menn på samme alder. Målet med dette arbeidet var å identifisere ...

    • Sex differences in cardiovascular outcome during progression of aortic valve stenosis 

      Cramariuc, Dana; Rogge, Barbara; Lønnebakken, Mai Tone; Boman, Kurt; Bahlmann, Edda; Gohlke-Bärwolf, Christa; Chambers, John B.; Pedersen, Terje Rolf; Gerdts, Eva (Peer reviewed; Journal article, 2015)
      Objective: Women with severe aortic valve stenosis (AS) have better LV systolic function and more concentric LV geometry than their male counterparts. However, sex differences in cardiovascular (CV) outcome during progression ...

    • Sex differences in oncogenic mutational processes 

      Li, Constance H.; Prokopec, Stephenie D.; Sun, Ren X.; Yousif, Fouad; Schmitz, Nathaniel; Boutros, Paul C.; Aure, Miriam Ragle; Børresen-Dale, Anne-Lise; Langerød, Anita; Wright, Derek W.; Baumhoer, Daniel; Bjerkehagen, Bodil; Garred, Øystein; Lingjærde, Ole Christian; Sauer, Torill; Zaikova, Olga; Myklebost, Ola; Knappskog, Stian; Vazquez, Miguel; Van Loo, Peter (Journal article; Peer reviewed, 2020)
      Sex differences have been observed in multiple facets of cancer epidemiology, treatment and biology, and in most cancers outside the sex organs. Efforts to link these clinical differences to specific molecular features ...

    • Sex differences in umbilical artery Doppler indices: A longitudinal study 

      Widnes, Christian; Flo, Kari; Wilsgaard, Tom; Kiserud, Torvid; Acharya, Ganesh (Peer reviewed; Journal article, 2018-04-18)
      Background Sexual dimorphism in placental size and function has been described. Whether this influences the clinically important umbilical artery (UA) waveform remains controversial, although a few cross-sectional studies ...

    • Sex disparity in acute myeloid leukaemia with FLT3 internal tandem duplication mutations: implications for prognosis 

      Hellesøy, Monica; Engen, Caroline Benedicte Nitter; Grob, Tim; Löwenberg, Bob; Valk, Peter J. M.; Gjertsen, Bjørn T. (Journal article; Peer reviewed, 2021)
      Incidence, molecular presentation and outcome of acute myeloid leukaemia (AML) are influenced by sex, but little attention has been directed at untangling sex-related molecular and phenotypic differences between female and ...

    • Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability 

      Lagou, Vasiliki; Mägi, Reedik; Hottenga, Jouke- Jan; Grallert, Harald; Perry, John R. B.; Bouatia-Naji, Nabila; Marullo, Letizia; Rybin, Denis V.; Jansen, Rick; Min, JL; Dimas, AS; Ulrich, Anna; Zudina, Liudmila; Gådin, Jesper R.; Jiang, Longda; Faggian, Alessia; Bonnefond, Amélie; Fadista, Joao; Stathopoulou, Maria G.; Isaacs, Aaron; Willems, Sara M.; Navarro, Pau; Tanaka, Toshiko; Jackson, Anne U.; Montasser, May E.; O’Connell, Jeff R.; Bielak, Lawrence F.; Webster, Rebecca J.; Saxena, Richa; Stafford, Jeanette M.; Pourcain, Beate St; Timpson, Nicholas J.; Salo, Perttu; Shin, SY; Amin, Najaf; Smith, Albert V.; Li, G; Verweij, Niek; Goel, Anuj; Ford, Ian; Johnson, Paul C. D.; Johnson, Toby; Kapur, Karen; Thorleifsson, Gudmar; Strawbridge, Rona J.; Rasmussen-Torvik, Laura J.; Esko, Tõnu; Mihailov, E; Fall, Tove; Fraser, Ross M; Mahajan, Anubha; Kanoni, Stavroula; Giedraitis, Vilmantas; Kleber, Marcus E.; Silbernagel, Günther; Meyer, Julia; Müller-Nurasyid, Martina; Ganna, Andrea; Sarin, Antti-Pekka; Yengo, Loic; Shungin, D; Luan, Jian’an; Horikoshi, Momoko; An, Ping; Sanna, Serena; Boettcher, Yvonne; Rayner, Nigel W; Nolte, Ilja M.; Zemunik, Tatijana; Iperen, Erik van; Kovacs, Peter; Hastie, Nicholas D.; Wild, Sarah H.; McLachlan, Stela; Campbell, Susan; Polasek, Ozren; Carlson, Olga; Egan, Josephine; Kiess, Wieland; Willemsen, Gonneke; Kuusisto, Johanna; Laakso, Markku; Dimitriou, M; Hicks, Andrew A.; Rauramaa, Rainer; Bandinelli, Stefania; Thorand, Barbara; Liu, Yongmei; Miljkovic, Iva; Lind, Lars; Doney, Alex; Perola, Markus; Hingorani, Aroon; Kivimaki, Mika; Kumari, Meena; Bennett, Amanda J.; Groves, Christopher J.; Herder, Christian; Koistinen, Heikki A.; Kinnunen, Leena; Faire, Ulf de; Bakker, Stephan J. L.; Uusitupa, Matti; Palmer, Colin N. A.; Jukema, J. Wouter; Sattar, Naveed; Pouta, Anneli; Snieder, Harold; Boerwinkle, Eric; Pankow, James S.; Magnusson, Patrik K.; Krus, Ulrika; Scapoli, Chiara; de Geus, Eco J. C. N.; Blüher, Matthias; Wolffenbuttel, Bruce H. R.; Province, Michael A.; Abecasis, Goncalo R.; Meigs, James B.; Hovingh, G. Kees; Lindström, Jaana; Wilson, JF; Wright, Alan F.; Dedoussis, George; Bornstein, Stefan R.; Schwarz, Peter E. H.; Tönjes, Anke; Winkelmann, Bernhard R.; Boehm, Bernhard O.; März, Winfried; Metspalu, Andres; Price, Jackie F.; Deloukas, Panos; Körner, Antje; Lakka, Timo A.; Keinanen-Kiukaanniemi, Sirkka M.; Saaristo, Timo E.; Bergman, Richard N.; Tuomilehto, Jaakko; Wareham, Nick; Langenberg, Claudia; Männistö, Satu; Franks, Paul W; Hayward, Caroline; Vitart, Veronique; Kaprio, Jaakko; Visvikis-Siest, Sophie; Balkau, Beverley; Altshuler, D; Rudan, Igor; Stumvoll, Michael; Campbell, Harry; van Duijn, Cornelia M.; Gieger, Christian; Illig, Thomas; Ferrucci, Luigi; Pedersen, Nancy L.; Pramstaller, Peter P.; Boehnke, Michael; Frayling, TM; Shuldiner, Alan R.; Peyser, Patricia A.; Kardia, Sharon L. R.; Palmer, Lyle J.; Penninx, Brenda W.; Meneton, Pierre; Harris, Tamara B.; Navis, Gerjan; Harst, Pim van der; Smith, George Davey; Forouhi, Nita G.; Loos, Ruth J. F.; Salomaa, Veikko; Soranzo, Nicole; Boomsma, Dorret I.; Groop, L; Tuomi, Tiinamaija; Hofman, Albert; Munroe, Patricia B.; Gudnason, Vilmundur; Siscovick, David S.; Watkins, Hugh; Lecoeur, Cecile; Vollenweider, Peter; Franco-Cereceda, Anders; Eriksson, Per; Jarvelin, Marjo-Riitta; Stefansson, Kari; Hamsten, Anders; Nicholson, George; Karpe, Fredrik; Dermitzakis, Emmanouil T.; Lindgren, Cecilia M.; McCarthy, Mark I.; Froguel, Philippe; Kaakinen, Marika A.; Lyssenko, Valeriya; Watanabe, Richard M.; Ingelsson, Erik; Florez, Jose C.; Dupuis, Josée; Barroso, I; Morris, Andrew P.; Prokopenko, Inga (Journal article; Peer reviewed, 2021)
      Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance in ...

    • Sex-related change in BMI of 15- to 16-year-old Norwegian girls in cross-sectional studies in 2002 and 2017 

      Bjertnæs, Asborg Sine Aanstad; Grundt, Jacob Holter; Juliusson, Petur Benedikt; Markestad, Trond Jacob; Strand, Tor A; Holten-Andersen, Mads Nikolaj (Peer reviewed; Journal article, 2019-11-12)
      Background: The prevalence of overweight and obesity (OWOB) has stabilized in some countries, but a portion of children with high body mass index (BMI) may have become heavier. This study aimed to describe the distributions ...

    • Sex-Specific Associations between Blood Pressure and Risk of Atrial Fibrillation Subtypes in the Tromsø Study 

      Espnes, Hilde; Ball, Jocasta; Løchen, Maja-Lisa; Wilsgaard, Tom; Njølstad, Inger; Mathiesen, Ellisiv B; Gerdts, Eva; Sharashova, Ekaterina (Journal article; Peer reviewed, 2021)
      The aim of this study was to explore sex-specific associations between systolic blood pressure (SBP), hypertension, and the risk of incident atrial fibrillation (AF) subtypes, including paroxysmal, persistent, and permanent ...

    • Sex-Specific Effect of Serum Lipids and Body Mass Index on Psychotic Symptoms, a Cross-Sectional Study of First-Episode Psychosis Patients 

      Gjerde, Priyanthi Borgen; Simonsen, Carmen Elisabeth; Lagerberg, Trine V.; Steen, Nils Eiel; Andreassen, Ole A.; Steen, Vidar M.; Melle, Ingrid (Journal article; Peer reviewed, 2021)
      Background: Schizophrenia is a disorder with considerable heterogeneity in course and outcomes, which is in part related to the patients' sex. Studies report a link between serum lipids, body mass index (BMI), and therapeutic ...

    • Sex-Specific Limitations in Physical Health in Primary Adrenal Insufficiency 

      Didriksen, Nora Møller; Sævik, Åse Bjorvatn; Sortland, Linn Solveig; Øksnes, Marianne; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2021)
      Background: Patients with primary adrenal insufficiency (PAI) suffer reduced quality of life (QoL), but comparisons with large-scale normative data are scarce. The clinical characteristics associated with reduced QoL are ...

    • Sex-specific reference ranges of cerebroplacental and umbilicocerebral ratios: A longitudinal study 

      Acharya, Ganesh; Ebbing, Cathrine; Karlsen, Henriette Odland; Kiserud, Torvid; Rasmussen, Svein (Peer reviewed; Journal article, 2020)
      Objectives: Observational studies have shown that low cerebroplacental ratio (CPR) values predict an increased risk of adverse perinatal outcome. The inverse ratio, i.e. the umbilicocerebral ratio (UCR), has been suggested ...

    • Sex-specific responses in glucose-insulin homeostasis and lipoprotein-lipid components after high-dose supplementation with marine n-3 PUFAs in abdominal obesity: a randomized double-blind crossover study 

      Laupsa-Borge, Johnny; Grytten, Elise; Bohov, Pavol; Bjørndal, Bodil; Strand, Elin; SKORVE, JON; Nordrehaug, Jan Erik; Berge, Rolf Kristian; Rostrup, Espen; Mellgren, Gunnar; Dankel, Simon N; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2023)
      Background: Clinical studies on effects of marine-derived omega-3 (n-3) polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and the plant-derived omega-6 (n-6) PUFA ...

    • Sex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the Tromsø Study 1994–2016 

      Sharashova, Ekaterina; Gerdts, Eva; Ball, Jocasta; Espnes, Hilde; Jacobsen, Bjarne K.; Kildal, Simon; Mathiesen, Ellisiv B.; Njølstad, Inger; Rosengren, Annika; Schirmer, Henrik; Wilsgaard, Tom; Løchen, Maja-Lisa (Journal article; Peer reviewed, 2023)
      Aims To explore sex-specific time trends in atrial fibrillation (AF) incidence and to estimate the impact of changes in risk factor levels using individual participant-level data from the population-based Tromsø Study ...