Blar i Department of Clinical Science på tittel

Viser treff 526-545 av 2312

    • Development of a Disease-Specific Quality of Life Questionnaire in Addison’s Disease 

      Løvås, Kristian; Curran, Suzanne; Øksnes, Marianne; Husebye, Eystein Sverre; Huppert, Felicia A.; Chatterjee, V. Krishna K. (Peer reviewed; Journal article, 2010-02)
      Context: Patients with Addison’s disease reproducibly self-report impairment in specific dimensions of general well-being questionnaires, suggesting particular deficiencies in health-related quality-of-life (HRQoL). ...

    • Development of a Framework and the Content for a Psychoeducational Internet-Delivered Intervention for Women after Treatment for Gynecological Cancer 

      Sekse, Ragnhild Johanne Tveit; Nordgreen, Tine; Flobak, Eivind; Lystrup, Morten; Braathen, Espen; Werner, Henrica Maria Johanna (Journal article; Peer reviewed, 2021)
      The number of women treated for gynecological cancer is increasing. At the same time, the duration of in-patient hospitalization has decreased, and follow-up with its primary focus on early recognition of recurrence does ...

    • Development of a novel, high-affinity ssDNA trypsin inhibitor 

      Malicki, Stanislaw; Ksiazek, Miroslaw; Majewski, Pawel; Pecak, Aleksandra; Mydel, Piotr Mateusz; Grudnik, Przemyslaw; Dubin, Grzegorz (Peer reviewed; Journal article, 2019)
      Inhibitors of serine proteases are not only extremely useful in the basic research but are also applied extensively in clinical settings. Using Systematic Evolution of Ligands by Exponential Enrichment (SELEX) approach we ...

    • Development of functional gastrointestinal disorders after Giardia lamblia infection 

      Hanevik, Kurt; Dizdar, Vernesa; Langeland, Nina; Hausken, Trygve (Peer reviewed; Journal article, 2009-04-21)
      Background: Functional gastrointestinal disorders (FGID) may occur following acute gastroenteritis. This long-term complication has previously not been described after infection with the non-invasive protozoan Giardia ...

    • Development of liposomal nanoencapsulation of lumefantrine with phosphatidylcholine/Tweens system 

      Fire, Berhane Zeresenay (Master thesis, 2021-05-20)

    • Development of lung diffusion to adulthood following extremely preterm birth 

      Satrell, Emma Elsa Carolina; Clemm, Hege Synnøve Havstad; Røksund, Ola Drange; Hufthammer, Karl Ove; Thorsen, Einar; Halvorsen, Thomas; Vollsæter, Maria (Journal article; Peer reviewed, 2022)
      Background: Gas exchange in extremely preterm (EP) infants must take place in fetal lungs. Childhood lung diffusing capacity of the lung for carbon monoxide (DLCO) is reduced; however, longitudinal development has not been ...

    • Development of prediction models for lymph node metastasis in endometrioid endometrial carcinoma 

      Berg, Hege Fredriksen; Ju, Zhenlin; Myrvold, Madeleine; Fasmer, Kristine Eldevik; Halle, Mari Kyllesø; Høivik, Erling Andre; Westin, Shannon; Trovik, Jone; Haldorsen, Ingfrid S.; Mills, Gordon B.; Krakstad, Camilla; Werner, Henrica Maria Johanna (Journal article; Peer reviewed, 2020-02-10)
      Background In endometrioid endometrial cancer (EEC), current clinical algorithms do not accurately predict patients with lymph node metastasis (LNM), leading to both under- and over-treatment. We aimed to develop models ...

    • Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension 

      Thorstensen, Christian W.; Clasen, Per-Erik; Rognstad, Stine; Haldsrud, Renate; Føreid, Siri; Helstrøm, Trine; Bergland, Ola Undrum; Halvorsen, Lene Vernås; Aune, Arleen; Olsen, Erik; Brobak, Karl Marius; Høieggen, Aud; Gustavsen, Ingebjørg G.; Larstorp, Anne Cecilie Kjeldsen; Søraas, Camilla Lund; Opdal, Mimi Stokke (Journal article; Peer reviewed, 2022)
      We developed three ultra-high pressure liquid chromatography coupled to mass spectrometry detection (UHPLC-MS/MS) methods to quantify 25 antihypertensive drugs in serum samples. Patient-reported drug lists were collected, ...

    • DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance 

      Zhang, Juan; Terán, Graciela; Popa, Mihaela-Lucia; Madapura, Harsha; Ladds, Marcus J.G.W.; Lianoudaki, Danai; Grünler, Jacob; Arsenian-Henriksson, Marie; McCormack, Emmet; Rottenberg, Martin Enrique; Catrina, Sergiu-Bogdan; Laín, Sonia; Darekar, Suhas (Journal article; Peer reviewed, 2021)
      Dihydroorotate dehydrogenase (DHODH) is essential for the de novo synthesis of pyrimidine ribonucleotides, and as such, its inhibitors have been long used to treat autoimmune diseases and are in clinical trials for cancer ...

    • Diabetes mellitus impact on fetal liver circulation, and new diagnostic options 

      Kiserud, Torvid (Journal article; Peer reviewed, 2023)
      While biometry and Doppler have proved useful in the management of fetal growth restriction, the same battery has been of less help in diabetic pregnancies. It is not surprising since the underlying pathophysiology is ...

    • Diabetes mellitus type 2; The incretin effect and interaction with the autonomic nervous system 

      Meling, Sondre Vatne (Doctoral thesis, 2023-09-22)
      Bakgrunn: Inkretineffekten er kroppens evne til økt insulinsekresjon når glukose inntas peroralt sammenliknet med administrert intravenøst, utløst av spesifikke hormoner fra tarmen. En redusert inkretineffekt leder til ...

    • Diagnosing pediatric malaria in Dar es Salaam, Tanzania. Clinical and laboratorial perspectives 

      Strøm, Gro Elizabeth Ann (Doctoral thesis, 2014-05-20)
      Malaria is an extensive global health issue with high morbidity and mortality. Diagnostics of malaria are challenging. Clinically malaria is indistinguishable from various other infectious diseases. Microscopy of blood ...

    • Diagnosis and follow-up of treatment of latent tuberculosis; the utility of the QuantiFERON-TB Gold In-tube assay in outpatients from a tuberculosis low-endemic country 

      Dyrhol-Riise, Anne Ma; Gran, Gerd; Wentzel-Larsen, Tore; Blomberg, Bjørn; Haanshuus, Christel Gill; Mørkve, Odd (Peer reviewed; Journal article, 2010-03-08)
      Background Interferon-gamma (IFN-γ) Release Assays (IGRA) are more specific than the tuberculosis skin test (TST) in the diagnosis of latent tuberculosis (TB) infection (LTBI). We present the performance of the QuantiFERON®-TB ...

    • Diagnostic accuracy of liquid biopsy in endometrial cancer 

      Łukasiewicz, Marta; Pastuszak, Krzysztof; Łapińska-Szumczyk, Sylwia; Różański, Robert; In ‘T Veld, Sjors G. J. G.; Bieńkowski, Michał; Stokowy, Tomasz; Ratajska, Magdalena; Best, Myron G.; Würdinger, Thomas; Żaczek, Anna J.; Supernat, Anna; Jassem, Jacek (Journal article; Peer reviewed, 2021)
      Background: Liquid biopsy is a minimally invasive collection of a patient body fluid sample. In oncology, they offer several advantages compared to traditional tissue biopsies. However, the potential of this method in ...

    • Diagnostic stewardship aiming at expectorated or induced sputum promotes microbial diagnosis in community-acquired pneumonia 

      Waagsbø, Bjørn; Buset, Eva Margrethe; Longva, Jørn-Åge; Bjerke, Merete; Bakkene, Birgitte; Ertesvåg, Anne-Stine; Holmen, Hanne; Nikodojevic, Marko; Tran, To Thy; Christensen, Andreas; Nilsen, Einar; Damås, Jan Kristian; Heggelund, Lars (Journal article; Peer reviewed, 2022)
      Purpose: Studies on aetiology of community-acquired pneumonia (CAP) vary in terms of microbial sampling methods, anatomical locations, and laboratory analyses, since no gold standard exists. In this large, multicentre, ...

    • Diagnostic testing of autonomous cortisol secretion in adrenal incidentalomas 

      Ueland, Grethe Åstrøm; Grinde, Thea; Methlie, Paal; Kelp, Oskar; Løvås, Kristian; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2020)
      Objective: Autonomous cortisol secretion (ACS) is a condition with ACTH-independent cortisol overproduction from adrenal incidentalomas (AI) or adrenal hyperplasia. The hypercortisolism is often mild, and most patients ...

    • The diagnostic utility of microscopic quality assessment of sputum samples in the era of rapid syndromic PCR testing 

      Markussen, Dagfinn Lunde; Ebbesen, Marit Helen; Serigstad, Sondre; Knoop, Siri Tandberg; Ritz, Christian; Bjørneklett, Rune Oskar; Kommedal, Øyvind; Jenum, Synne; Ulvestad, Elling; Grewal, Harleen (Journal article; Peer reviewed, 2023)
      This prospective study assessed the value of initial microscopy evaluation of sputum samples submitted for rapid syndromic PCR-based testing. Bacterial detections by the BioFire FilmArray Pneumonia Panel plus in 126 high- ...

    • Diagnostic validity of fatal cerebral strokes and coronary deaths 

      Gulsvik, Anne K.; Gulsvik, Amund; Svendsen, Einar; Mæhle, Bjørn Ove; Thelle, Dag S.; Wyller, Torgeir B. (Peer reviewed; Journal article, 2011-03)
      Mortality statistics represent important endpoints in epidemiological studies. The diagnostic validity of cerebral stroke and ischemic heart disease recorded as the underlying cause of death in Norwegian mortality statistics ...

    • Diagnostikk og behandling av autoimmun hepatitt 

      Vesterhus, Mette Nåmdal; Wiencke, Kristine; Haukeland, John Willy; Frigstad, Svein Oskar; Karlsen, Lars Normann; Jørgensen, Kristin Kaasen; Folseraas, Trine (Journal article; Peer reviewed, 2021)
      Autoimmun hepatitt er en kronisk leversykdom som ubehandlet kan føre til levercirrhose og leversvikt. Majoriteten av pasientene responderer godt på standard immunsuppressiv behandling, men noen opplever bivirkninger eller ...

    • Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat 

      Hole, Lisa Drange; Larsen, Terje H.; Fossan, Kjell Ove; Limé, Fredrik; Schjøtt, Jan (Peer reviewed; Journal article, 2014-05-27)
      Aim: Chemotherapy with doxorubicin is limited by cardiotoxicity. Free radical generation and mitochondrial dysfunction are thought to contribute to doxorubicin-induced cardiac failure. In this study we wanted to investigate ...