Browsing Department of Clinical Science by Title
Now showing items 615-634 of 2313
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Early Induction of Cross-Reactive CD8+ T-Cell Responses in Tonsils After Live-Attenuated Influenza Vaccination in Children
(Journal article; Peer reviewed, 2020)Background Live-attenuated influenza vaccine (LAIV) was licensed for prophylaxis of children 2–17 years old in Europe in 2012 and is administered as a nasal spray. Live-attenuated influenza vaccine induces both mucosal ... -
Early life environment and snoring in adulthood
(Peer reviewed; Journal article, 2008-08-22)Background: To our knowledge, no studies of the possible association of early life environment with snoring in adulthood have been published. We aimed to investigate whether early life environment is associated with snoring ... -
Early life growth and associations with lung function and bronchial hyperresponsiveness at 11-years of age
(Journal article; Peer reviewed, 2021)Low birthweight and being born small-for-gestational age (SGA) are linked to asthma and impaired lung function. Particularly, poor intrauterine growth followed by rapid catch-up growth during childhood may predispose for ... -
Early manifestations of genetic risk for neurodevelopmental disorders
(Journal article; Peer reviewed, 2021)Background: Attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder (autism) and schizophrenia are highly heritable neurodevelopmental disorders, affecting the lives of many individuals. It is important ... -
Early outcome and restenosis after coronary stenting : intervention with stent-coatings, antioxidants and radiation
(Doctoral thesis, 2007-03-16) -
Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
(Journal article; Peer reviewed, 2022)Background: Immune checkpoint blockade (ICB) results in radiologic tumour response dynamics that differ from chemotherapy efficacy measures and require an early signal of clinical utility. Methods: Previously untreated, ... -
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
(Journal article; Peer reviewed, 2023)Aberrant pro-survival signaling is a hallmark of cancer cells, but the response to chemotherapy is poorly understood. In this study, we investigate the initial signaling response to standard induction chemotherapy in a ... -
Early Response in Cellulitis: A Prospective Study of Dynamics and Predictors
(Peer reviewed; Journal article, 2016)Background: Skin and soft tissue infections are common reasons for medical care. Use of broad-spectrum therapy and costs have increased. Assessment of early treatment response has been given a central role both in clinical ... -
Early surfactant and non-invasive ventilation versus intubation and surfactant: a propensity score-matched national study
(Journal article; Peer reviewed, 2022)Objective: To compare outcome after less invasive surfactant administration (LISA) and primary endotracheal intubation (non-LISA) in infants born before gestational age (GA) 28 weeks. Setting: All neonatal intensive ... -
Early vascular aging in young and middle-aged ischemic stroke patients: The Norwegian stroke in the young study
(Peer reviewed; Journal article, 2014-11-18)Background: Ischemic stroke survivors have high risk of cardiovascular morbidity and mortality even at young age, suggesting that early arterial aging is common among such patients. Methods: We measured aortic stiffness ... -
Early-Onset Sepsis in Neonates - A Population-Based Study in South-West Norway From 1996 to 2018
(Journal article; Peer reviewed, 2021)Background: The epidemiology of early-onset sepsis (EOS) may change over time. Longitudinal surveillance of causative pathogens, antibiotic susceptibility patterns and antibiotic therapy is important for optimal therapy ... -
The effect of antibiotic stewardship interventions with stakeholder involvement in hospital settings: A multicentre, cluster randomized controlled intervention study
(Peer reviewed; Journal article, 2018-09-10)Background: There is limited evidence from multicenter, randomized controlled studies to inform planning and implementation of antibiotic stewardship interventions in hospitals. Methods: A cluster randomized, controlled, ... -
The Effect of Biological Treatment on Fatigue in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis
(Journal article; Peer reviewed, 2023)Background: Fatigue is a frequent complaint in patients with inflammatory bowel disease. Biological drugs have demonstrated beneficial effects on some extraintestinal manifestations, but the effect on fatigue is not ... -
The effect of drug-eluting stents on target lesion revascularization in native coronary arteries: results from the NORSTENT randomized study
(Journal article; Peer reviewed, 2020)Background: The NORSTENT trial randomized 9,013 patients to percutaneous coronary intervention (PCI) with a drug-eluting stent (DES) or bare-metal stent (BMS) with 5-year follow-up. No difference was found in the composite ... -
The effect of electroconvulsive therapy (ECT) on serum kynurenine pathway metabolites in late-life depression
(Journal article; Peer reviewed, 2023)Background: Depression is reportedly associated with alterations in kynurenine pathway metabolites (kynurenines). Several kynurenines are involved in glutamate signaling, and some have potentially neurotoxic effects while ... -
Effect of Folic Acid Supplementation on Levels of Circulating Monocyte Chemoattractant Protein-1 and the Presence of Intravascular Ultrasound Derived Virtual Histology Thin-Cap Fibroatheromas in Patients with Stable Angina Pectoris
(Peer reviewed; Journal article, 2013-07-25)Background: Virtual Histology Intravascular Ultrasound (VH–IVUS) may be used to detect early signs of unstable coronary artery disease. Monocyte Chemoattractant Protein-1 (MCP-1) is linked with coronary atherosclerosis and ... -
Effect of genetic variability in 20 pharmacogenes on concentrations of tamoxifen and its metabolites
(Journal article; Peer reviewed, 2021)Background: Tamoxifen, as a treatment of estrogen receptor positive (ER+) breast cancer, is a weak anti-estrogen that requires metabolic activation to form metabolites with higher anti-estrogenic activity. Endoxifen is the ... -
The Effect of Lean-Seafood and Non-Seafood Diets on Fasting and Postprandial Serum Metabolites and Lipid Species: Results from a Randomized Crossover Intervention Study in Healthy Adults
(Peer reviewed; Journal article, 2018-05-11)The metabolic effects associated with intake of different dietary protein sources are not well characterized. We aimed to elucidate how two diets that varied in main protein sources affected the fasting and postprandial ... -
The effect of low dose marine protein hydrolysates on short-term recovery after high intensity performance cycling: A double-blinded crossover study
(Peer reviewed; Journal article, 2019)Background: Knowledge of the effect of marine protein hydrolysate (MPH) supplementation to promote recovery after high intensity performance training is scarce. The aim of this study was to examine the effect of MPH ...