Blar i Department of Clinical Science på tittel
Viser treff 70-89 av 2316
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Ancestrally Duplicated Conserved Noncoding Element Suggests Dual Regulatory Roles of HOTAIR in cis and trans
(Journal article; Peer reviewed, 2020-04)HOTAIR was proposed to regulate either HoxD cluster genes in trans or HoxC cluster genes in cis, a mechanism that remains unclear. We have identified a 32-nucleotide conserved noncoding element (CNE) as HOTAIR ancient ... -
Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival
(Peer reviewed; Journal article, 2017)Aneuploidy is a widely studied prognostic marker in endometrial cancer (EC), however, not implemented in clinical decision-making. It lacks validation in large prospective patient cohorts adjusted for currently standard ... -
Angiopoietin-2 and angiopoietin-like 4 protein provide prognostic information in patients with suspected acute coronary syndrome
(Journal article; Peer reviewed, 2021)Background Plasma levels of angiopoietin-2 (ANGPT2) and angiopoietin-like 4 protein (ANGPTL4) reflect different pathophysiological aspects of cardiovascular disease. We evaluated their association with outcome in a ... -
Anthropometrics of neonates born to mothers with PCOS with metformin or placebo exposure in utero
(Journal article; Peer reviewed, 2023)Introduction: Fetal growth may be affected by both maternal polycystic ovary syndrome (PCOS) and metformin therapy. Here, we explore the effect of intrauterine metformin exposure on birth anthropometrics of infants born ... -
Anti-HMGB1 auto-Abs influence fatigue in patients with Crohn’s disease
(Journal article; Peer reviewed, 2021)Fatigue is common in all chronic inflammatory and autoimmune diseases. A conceptual model for understanding the biological basis of fatigue describes it as being a part of the sickness behaviour response generated by ... -
Anti-Interferon Autoantibodies in Autoimmune Polyendocrinopathy Syndrome Type 1
(Peer reviewed; Journal article, 2006-06-13)Background The autoimmune regulator (AIRE) gene influences thymic self-tolerance induction. In autoimmune polyendocrinopathy syndrome type 1 (APS1; OMIM 240300), recessive AIRE mutations lead to autoimmunity targetting ... -
Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia
(Peer reviewed; Journal article, 2016-12-01)Mutated nucleophosmin 1 (NPM1) acts as a proto-oncogene and is present in ~30% of patients with acute myeloid leukemia (AML). Here we examined the in vitro and in vivo anti-leukemic activity of the NPM1 and chromosome ... -
Antibiotic Use in a Cohort of Norwegian Children and Neonates Before, During and After Hospitalisation : Exploring focus areas for antibiotic stewardship
(Doctoral thesis, 2022-11-22)Bakgrunn: Rasjonell antibiotikabruk blant barn er essensielt for å unngå økende antibiotikaresistens samt forstyrrelser i deres normale bakterieflora. Formål: Hensikten med dette prosjektet var å tilegne oss en bedre ... -
Antibiotic use in children before, during and after hospitalisation
(Journal article; Peer reviewed, 2022)Purpose: To investigate ambulatory antibiotic use in children during 1 year before and 1 year after in-hospital antibiotic exposure compared to children from the general population that had not received antibiotics ... -
Antibiotika og antibakteriellsubstans, ciprofloxacin og triclosan i jord og husdyrgjødsel
(Master thesis, 2009-05-20)The goal of this thesis was to get a better understanding of how triclosan and ciprofloxacin behave in the environment, and also to see if a contamination of these substances exists in a variety of matrixes. The objective ... -
Antibiotikabehandling ved KOLS-forverring ved Haukeland Universitetssykehus
(Master thesis, 2022-05-20) -
Antibiotikabehandling ved samfunnservervet pneumoni i sykehus
(Master thesis, 2022-05-20) -
Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self-reported severity and duration of illness
(Peer reviewed; Journal article, 2018-12-09)Background: A population‐based pregnancy cohort was established in Norway to study potential effects of exposure to the 2009 influenza pandemic or pandemic vaccination during pregnancy. Objectives: We studied maternal ... -
Antibody responses after influenza and SARS-CoV-2 vaccination and infection: Lessons across the ages
(Doctoral thesis, 2023-10-23)Influensa A og SARS-CoV-2 er RNA-baserte luftvegsvirus som forårsakar pandemiar og muterer raskt for å oppretthalde ein kontinuerleg sirkulasjon. Eit komplekst samspel mellom immunresponsar hjå verten og viruset er forma ... -
Antibody-mediated interferences affecting cardiac troponin assays: recommendations from the IFCC Committee on Clinical Applications of Cardiac Biomarkers
(Journal article; Peer reviewed, 2023)The International Federation of Clinical Chemistry Committee on Clinical Applications of Cardiac Biomarkers (IFCC C-CB) provides educational documents to facilitate the interpretation and use of cardiac biomarkers in ... -
The antihypertensive MTHFR gene polymorphism rs17367504-G is a possible novel protective locus for preeclampsia
(Peer reviewed; Journal article, 2016-01)Objective: Preeclampsia is a complex heterogeneous disease commonly defined by new-onset hypertension and proteinuria in pregnancy. Women experiencing preeclampsia have increased risk for cardiovascular diseases (CVD) later ... -
Antimicrobial therapy of community-acquired pneumonia during stewardship efforts and a coronavirus pandemic: an observational study
(Journal article; Peer reviewed, 2022-10-14)Background: Community-acquired pneumonia (CAP) is the most frequent infection diagnosis in hospitals. Antimicrobial therapy for CAP is depicted in clinical practice guidelines, but adherence data and effect of antibiotic ... -
Anxiety and depression in patients aged 80 years and older following aortic valve therapy. A six‑month follow‑up study
(Journal article; Peer reviewed, 2023)Background Little is known about mental health following advanced cardiac procedures in the oldest patients. Aims To study changes in anxiety and depression from baseline to one- and six-month follow-up in older ... -
Aortic root dilatation in hypertensive patients with left ventricular hypertrophy–application of a new multivariate predictive model. The Life Study
(Journal article, 2022)Background: Available nomograms to predict aortic root (AoR) diameter for body surface area have limitations. The purpose of this study was to evaluate the use of a new multivariate predictive model to identify AoR dilatation ... -
APOBEC3A/B deletion polymorphism and endometrial cancer risk
(Journal article; Peer reviewed, 2022)Background A common 30 kb deletion affecting the APOBEC3A and APOBEC3B genes has been linked to increased APOBEC activity and APOBEC-related mutational signatures in human cancers. The role of this deletion as a cancer ...