Browsing Department of Clinical Science by Title
Now showing items 2300-2319 of 2395
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UGT1A4 og UGT2B15 enkeltnukleotidpolymorfismer. Etablering av real time PCR metoder og betydning for tamoxifen metabolisme
(Master thesis, 2008-06-02)Brystkreft er den vanligste kreftformen blant kvinner i Norge og adjuvant tamoxifenbehandling er vist å øke tilbakefallsfri og total overlevelse. Den interinidividuelle varaiasjonen i effekt og bivirkninger av tamoxifen ... -
Ultraprosessert mat burde være et kostråd: JA
(Journal article, 2023) -
Ultrasonography of major salivary glands in primary and juvenile Sjögren’s syndrome
(Doctoral thesis, 2019-06-07)Background: Primary Sjögrens’s syndrome (pSS) is a systemic autoimmune disease, mainly affecting the salivary and lacrimal glands. Primary SS can also affect the younger population and when it does, the denomination is ... -
Ultrasound in Crohn’s Disease - bowel wall characteristics and perfusion estimates using microbubbles
(Doctoral thesis, 2013-01-18)Crohn’s disease (CD) is a chronic inflammatory bowel disease which often presents early in life and sometimes can be debilitating. The patients need frequent diagnostic work-up to assess disease activity, location, extent ... -
Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells
(Journal article; Peer reviewed, 2020)Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death worldwide. Poor drug delivery to tumours is thought to limit chemotherapeutic treatment efficacy. Sonoporation combines ultrasound (US) and microbubbles ... -
Ultraviolet radiation as a predictor of sex hormone levels in postmenopausal women: A European multi-center study (ECRHS)
(Journal article; Peer reviewed, 2021)Background Solar ultraviolet radiation (UVR) affects the body through pathways that exhibit positive as well as negative health effects such as immunoregulation and vitamin D production. Different vitamin D metabolites ... -
Understanding fatigue in Sjögren’s Syndrome: Outcome measures, biomarkers and possible interventions
(Journal article; Peer reviewed, 2021)Sjögren’s syndrome (SS) is an autoimmune disease affecting the salivary and lacrimal glands. Symptoms range from dryness to severe extra-glandular disease involving manifestations in the skin, lungs, nervous system, and ... -
Understanding the Effects of Antipsychotics on Appetite Control
(Journal article; Peer reviewed, 2021)Antipsychotic drugs (APDs) represent a cornerstone in the treatment of schizophrenia and other psychoses. The effectiveness of the first generation (typical) APDs are hampered by so-called extrapyramidal side effects, and ... -
Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome – State of the art: Report of the 2nd international meeting at the Charité Fatigue Center
(Journal article; Peer reviewed, 2023)Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a devastating disease affecting millions of people worldwide. Due to the 2019 pandemic of coronavirus disease (COVID-19), we are facing a significant increase ... -
Undersøke sammenhengen mellom jernstatus og jernabsorpsjon. Sammenligning av friske og pasienter med hemokromatose
(Master thesis, 2008-06-01)Jern er et essensielt spormetall som vi har ca 3-4 g av i kroppen. Jern inngår i flere proteiner, der hemoglobin er det viktigste. Jern er også delaktig i flere redoksreaksjoner i kroppen vår. Vi trenger daglig et tilskudd ... -
Undersøkelse av formuleringstekniske aspekter for Krembase NAF og Krembase NAF som grunnlag i magistrell fremstilling
(Master thesis, 2024-06-03)Krembase NAF er et produkt med lang historie i norske apotek, men det er likevel begrenset informasjon tilgjengelig om de formuleringstekniske egenskapene. I denne oppgaven er derfor formuleringens robusthet undersøkt, og ... -
Unexplained chronic liver disease in Ethiopia: a cross-sectional study
(Peer reviewed; Journal article, 2018-02-13)Background: Hepatitis B virus (HBV) infection is assumed to be the major cause of chronic liver disease (CLD) in sub-Saharan Africa. The contribution of other aetiological causes of CLD is less well documented and hence ... -
Unexplained, self-reported food hypersensitivity. Explorative studies on mechanisms of abdominal symptom generation
(Doctoral thesis, 2010-10-08)Background: Self-reported food hypersensitivity remains unexplained in most cases. Abdominal symptoms, typically consistent with the irritable bowel syndrome (IBS), are common in patients with such unexplained, self-reported ... -
Unperturbed cytotoxic lymphocyte phenotype and function in myalgic encephalomyelitis/chronic fatigue syndrome patients
(Peer reviewed; Journal article, 2017-06-26)Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a debilitating disorder linked to diverse intracellular infections as well as physiological stress. Cytotoxic lymphocytes combat intracellular infections. ... -
Unsupervised clustering of missense variants in HNF1A using multidimensional functional data aids clinical interpretation
(Journal article; Peer reviewed, 2020-10-01)Exome sequencing in diabetes presents a diagnostic challenge because depending on frequency, functional impact, and genomic and environmental contexts, HNF1A variants can cause maturity-onset diabetes of the young (MODY), ... -
Unveiling sex bias and adverse neonatal outcomes in ultrasound estimation of gestational age: A population-based cohort study
(Journal article; Peer reviewed, 2024)Background Gestational age estimation by second-trimester ultrasound biometry introduces systematic errors due to sex differences in early foetal growth, consequently increasing the risk of adverse neonatal outcomes. ... -
Unveiling the Complexities: Patients’ and Healthcare Providers’ Perspectives on Understanding and Managing Ovarian Cancer
(Doctoral thesis, 2024-06-28)Bakgrunn: Eggstokkreft er en alvorlig og kompleks sykdom, som fremdeles har en dårlig prognose til tross for betydelige medisinske fremskritt, inkludert innen presisjonsonkologi. Pasienter med eggstokkreft gjennomgår et ... -
Update on primary sclerosing cholangitis
(Peer reviewed; Journal article, 2013-09)Primary sclerosing cholangitis (PSC) remains one of the most challenging conditions of clinical hepatology. There has been a steady growth in research to overcome this fact and the present review aims at summarizing the ... -
Updated total IgE reference intervals in Norwegian adults
(Journal article; Peer reviewed, 2023)Background It is important and expected of laboratories to provide updated reference intervals to the clinician. As no recent publications report adult total IgE reference intervals on a Scandinavian population, the aim ... -
The urban-rural gradient in asthma: A population-based study in Northern Europe
(Peer reviewed; Journal article, 2015-12-30)The early life environment appears to have a persistent impact on asthma risk. We hypothesize that environmental factors related to rural life mediate lower asthma prevalence in rural populations, and aimed to investigate ...