Blar i Department of Clinical Science på tittel

Viser treff 2226-2245 av 2310

    • Understanding fatigue in Sjögren’s Syndrome: Outcome measures, biomarkers and possible interventions 

      Mæland, Elisabeth; Miyamoto, Samira T.; Hammenfors, Daniel; Valim, Valeria; Jonsson, Malin Viktoria (Journal article; Peer reviewed, 2021)
      Sjögren’s syndrome (SS) is an autoimmune disease affecting the salivary and lacrimal glands. Symptoms range from dryness to severe extra-glandular disease involving manifestations in the skin, lungs, nervous system, and ...

    • Understanding the Effects of Antipsychotics on Appetite Control 

      Mukherjee, Sayani; Skrede, Silje; Milbank, Edward; Andriantsitohaina, Ramaroson; López, Miguel; Fernø, Johan (Journal article; Peer reviewed, 2021)
      Antipsychotic drugs (APDs) represent a cornerstone in the treatment of schizophrenia and other psychoses. The effectiveness of the first generation (typical) APDs are hampered by so-called extrapyramidal side effects, and ...

    • Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome – State of the art: Report of the 2nd international meeting at the Charité Fatigue Center 

      Steiner, Sophie; Fehrer, Annick; Hoheisel, Friederike; Schoening, Simon; Aschenbrenner, Anna; Babel, Nina; Bellmann-Strobl, Judith; Finke, Carsten; Fluge, Øystein; Froehlich, Laura; Goebel, Andreas; Grande, Bettina; Haas, Johannes-Peter; Hohberger, Bettina; Jason, Leonard A.; Komaroff, Anthony L.; Lacerda, Eliana; Liebl, Max; Maier, Andrea; Mella, Olav; Nacul, Luis; Paul, Friedemann; Prusty, Bhupesh K.; Puta, Christian; Riemekasten, Gabriela; Ries, Wolfgang; Rowe, Peter C.; Sawitzki, Birgit; Shoenfeld, Yehuda; Schultze, Joachim L.; Seifert, Martina; Sepúlveda, Nuno; Sotzny, Franziska; Stein, Elisa; Stingl, Michael; Ufer, Friederike; Veauthier, Christian; Westermeier, Francisco; Wirth, Klaus; Wolfarth, Bernd; Zalewski, Pawel; Behrends, Uta; Scheibenbogen, Carmen (Journal article; Peer reviewed, 2023)
      Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a devastating disease affecting millions of people worldwide. Due to the 2019 pandemic of coronavirus disease (COVID-19), we are facing a significant increase ...

    • Undersøke sammenhengen mellom jernstatus og jernabsorpsjon. Sammenligning av friske og pasienter med hemokromatose 

      Bø, Eirik Svandal (Master thesis, 2008-06-01)
      Jern er et essensielt spormetall som vi har ca 3-4 g av i kroppen. Jern inngår i flere proteiner, der hemoglobin er det viktigste. Jern er også delaktig i flere redoksreaksjoner i kroppen vår. Vi trenger daglig et tilskudd ...

    • Unexplained chronic liver disease in Ethiopia: a cross-sectional study 

      Orlien, Stian Magnus Staurung; Ismael, Nejib Yusuf; Ahmed, Tekabe Abdosh; Berhe, Nega; Lauritzen, Trine; Roald, Borghild; Goldin, Robert David; Stene-Johansen, Kathrine; Dyrhol-Riise, Anne Ma; Gundersen, Svein Gunnar; Morgan, Marsha Yvonne; Johannessen, Asgeir (Peer reviewed; Journal article, 2018-02-13)
      Background: Hepatitis B virus (HBV) infection is assumed to be the major cause of chronic liver disease (CLD) in sub-Saharan Africa. The contribution of other aetiological causes of CLD is less well documented and hence ...

    • Unexplained, self-reported food hypersensitivity. Explorative studies on mechanisms of abdominal symptom generation 

      Valeur, Jørgen (Doctoral thesis, 2010-10-08)
      Background: Self-reported food hypersensitivity remains unexplained in most cases. Abdominal symptoms, typically consistent with the irritable bowel syndrome (IBS), are common in patients with such unexplained, self-reported ...

    • Unperturbed cytotoxic lymphocyte phenotype and function in myalgic encephalomyelitis/chronic fatigue syndrome patients 

      Theorell, Jakob; Bileviciute-Ljungar, Indre; Tesi, Bianca; Schlums, Heinrich; Johnsgaard, Mette Sophie; Asadi-Azarbaijani, Babak; Strand, Elin Bolle; Bryceson, Yenan (Peer reviewed; Journal article, 2017-06-26)
      Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a debilitating disorder linked to diverse intracellular infections as well as physiological stress. Cytotoxic lymphocytes combat intracellular infections. ...

    • Unsupervised clustering of missense variants in HNF1A using multidimensional functional data aids clinical interpretation 

      Althari, Sara; Najmi, Laeya Abdoli; Bennett, Amanda J.; Aukrust, Ingvild; Rundle, Jana K.; Colclough, Kevin; Molnes, Janne; Kaci, Alba; Nawaz, Sameena; van der Lugt, Timme; Hassanali, Neelam; Mahajan, Anubha; Molven, Anders; Ellard, Sian; McCarthy, Mark I.; Bjørkhaug, Lise; Njølstad, Pål Rasmus; Gloyn, Anna L. (Journal article; Peer reviewed, 2020-10-01)
      Exome sequencing in diabetes presents a diagnostic challenge because depending on frequency, functional impact, and genomic and environmental contexts, HNF1A variants can cause maturity-onset diabetes of the young (MODY), ...

    • Unveiling sex bias and adverse neonatal outcomes in ultrasound estimation of gestational age: A population-based cohort study 

      Einum, Anders; Sørbye, Linn Marie; Nilsen, Roy Miodini; Ebbing, Cathrine; Morken, Nils-Halvdan (Journal article; Peer reviewed, 2024)
      Background Gestational age estimation by second-trimester ultrasound biometry introduces systematic errors due to sex differences in early foetal growth, consequently increasing the risk of adverse neonatal outcomes. ...

    • Update on primary sclerosing cholangitis 

      Karlsen, Tom Hemming; Boberg, Kirsten Muri (Peer reviewed; Journal article, 2013-09)
      Primary sclerosing cholangitis (PSC) remains one of the most challenging conditions of clinical hepatology. There has been a steady growth in research to overcome this fact and the present review aims at summarizing the ...

    • Updated total IgE reference intervals in Norwegian adults 

      Vinnes, Erik Wilhelm; Skarbø, Birthe Rochlenge Skarbø; Wentzel-Larsen, Tore; Sylte, Marit Sverresdotter; Apelseth, Torunn Oveland (Journal article; Peer reviewed, 2023)
      Background It is important and expected of laboratories to provide updated reference intervals to the clinician. As no recent publications report adult total IgE reference intervals on a Scandinavian population, the aim ...

    • The urban-rural gradient in asthma: A population-based study in Northern Europe 

      Timm, Signe; Frydenberg, Morten; Janson, Christer; Campbell, Brittany; Forsberg, Bertil; Gíslason, Þórarinn; Holm, Mathias; Jõgi, Rain; Omenaas, Ernst; Sigsgaard, Torben; Svanes, Cecilie; Schlünssen, Vivi (Peer reviewed; Journal article, 2015-12-30)
      The early life environment appears to have a persistent impact on asthma risk. We hypothesize that environmental factors related to rural life mediate lower asthma prevalence in rural populations, and aimed to investigate ...

    • Urinary excretion of homocysteine thiolactone and the risk of acute myocardial infarction in coronary artery disease patients: the WENBIT trial 

      Borowczyk, Kamila; Piechocka, Justyna; Głowacki, Rafał; Dhar, Indu; Midttun, Øivind; Tell, Grethe S.; Ueland, Per Magne; Nygård, Ottar; Jakubowski, Hieronim (Peer reviewed; Journal article, 2018)
      Objectives: No individual homocysteine (Hcy) metabolite has been studied as a risk marker for coronary artery disease (CAD). Our objective was to examine Hcy‐thiolactone, a chemically reactive metabolite generated by ...

    • Urinary Marker Profiles in Heart Failure with Reduced Versus Preserved Ejection Fraction 

      Streng, Koen W.; Hillege, Hans L.; ter Maaten, Jozine M.; van Veldhuisen, Dirk J.; Dickstein, Kenneth; Samani, Nilesh J.; Ng, Leong L.; Metra, Marco; Filippatos, Gerasimos S.; Ponikowski, Piotr; Zannad, Faiez; Anker, Stefan D.; van der Meer, Peter; Lang, Chim C.; Voors, Adriaan A.; Damman, Kevin (Journal article; Peer reviewed, 2023)
      Background Recent data suggest different causes of renal dysfunction between heart failure with reduced (HFrEF) versus preserved ejection fraction (HFpEF). We therefore studied a wide range of urinary markers reflecting ...

    • The use of 16S rRNA targeted next generation sequencing in diagnostics of polymicrobial invasive infections 

      Dyrhovden, Ruben (Doctoral thesis, 2023-08-21)
      16S rRNA dypsekvensering muliggjør, som vist i flere vitenskapelige arbeider, en mer fullstendig karakterisering av komplekse bakterielle mikrobiota enn det som kan oppnås ved tradisjonelle, dyrkningsbaserte, mikrobiologiske ...

    • Use of antihistamines before or during pregnancy and risk of early-onset pre-eclampsia in allergic women: a population-based cohort study 

      Sande, Anne Kvie; Torkildsen, Erik Andreas; Sande, Ragnar; Dalen, Ingvild; Danielsson, Kim Christian; Morken, Nils-Halvdan (Journal article; Peer reviewed, 2022)
      Objective: We have previously found that allergy is a risk factor for early-onset pre-eclampsia. The aim of this study was to assess the association between pregestational maternal use of antihistamines and early-onset ...

    • Use of conditional centiles of middle cerebral artery pulsatility index and cerebroplacental ratio in the prediction of adverse perinatal outcomes 

      Karlsen, Henriette Odland; Ebbing, Cathrine; Rasmussen, Svein; Kiserud, Torvid; Johnsen, Synnøve L. (Journal article, 2016-06)
      Introduction. Centiles of middle cerebral artery pulsatility index and cerebroplacental ratio are useful for predicting adverse perinatal outcomes. A ‘conditional centile’ is conditioned by a previous measurement reflecting ...

    • Use of inhaled ipratropium bromide to improve exercise-induced laryngeal obstruction cannot be recommended 

      Muralitharan, Praveen; Carlsen, Petter; Hilland, Magnus; Delestre-Levai, Irisz; Vollsæter, Maria; Hufthammer, Karl Ove; Engan, Mette; Røksund, Ola Drange; Halvorsen, Thomas; Clemm, Hege Synnøve Havstad (Journal article; Peer reviewed, 2023)
      Introduction: Exercise-induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young adults. Current management generally consists of breathing advice, speech therapy, inspiratory muscle ...

    • Use of loop diuretics is associated with increased mortality in patients with suspected coronary artery disease, but without systolic heart failure or renal impairment: an observational study using propensity score matching 

      Schartum-Hansen, Hall; Løland, Kjetil Halvorsen; Svingen, Gard Frodahl Tveitevåg; Seifert, Reinhard; Pedersen, Eva Ringdal; Nordrehaug, Jan Erik; Bleie, Øyvind; Ebbing, Marta; Berge, Christ; Nilsen, Dennis W.T.; Nygård, Ottar (Peer reviewed; Journal article, 2015-06-01)
      Background Loop diuretics are widely used in patients with heart and renal failure, as well as to treat hypertension and peripheral edema. However, there are no randomized, controlled trials (RCT) evaluating their long ...

    • Use of microbiology tests in the era of increasing AMR rates- a multicentre hospital cohort study 

      Skodvin, Brita; Wathne, Jannicke Slettli; Lindemann, Paul Christoffer; Harthug, Stig; Nilsen, Roy Miodini; Charani, Esmita; Syre, Heidi; Kittang, Bård Reiakvam; Kleppe, Lars Kåre Selland; Smith, Ingrid (Peer reviewed; Journal article, 2019-02-04)
      Background: Effective use of microbiology test results may positively influence patient outcomes and limit the use of broad-spectrum antibiotics. However, studies indicate that their potential is not fully utilized. We ...