Blar i Department of Clinical Science på tittel
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A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
(Journal article; Peer reviewed, 2021)Breakpoint Cluster Region-Abelson kinase (BCR–Abl) is a driver oncogene that causes chronic myeloid leukemia and a subset of acute lymphoid leukemias. Although tyrosine kinase inhibitors provide an effective treatment for ... -
Cell type specificity of neurovascular coupling in cerebral cortex
(Peer reviewed; Journal article, 2016-05-31)Identification of the cellular players and molecular messengers that communicate neuronal activity to the vasculature driving cerebral hemodynamics is important for (1) the basic understanding of cerebrovascular regulation ... -
Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study
(Peer reviewed; Journal article, 2016-02-25)Background: Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). ... -
Ceramide stearic to palmitic acid ratio predicts incident diabetes
(Peer reviewed; Journal article, 2018-03-15)Aims/hypothesis Ceramide lipids have a role in the development of insulin resistance, diabetes and risk of cardiovascular disease. Here we investigated four ceramides and their ratios to find the best predictors of incident ... -
Cerebral Venous Thrombosis and Hyperthyroidism
(Peer reviewed; Journal article, 2014-01-16)Cerebral venous thrombosis (CVT) is mostly caused by pro-thrombotic factors. Hyperthyroidism is not a wellknown risk factor. We present a case report on a 17 year old girl who developed life-threatening CVT after Graves’ ... -
Cerebroplacental ratio in predicting adverse perinatal outcome: a meta-analysis of individual participant data
(Journal article; Peer reviewed, 2021)Objective To investigate if cerebroplacental ratio (CPR) adds to the predictive value of umbilical artery pulsatility index (UA PI) alone – standard of practice – for adverse perinatal outcome in singleton pregnancies. Design ... -
Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip fracture patients
(Journal article; Peer reviewed, 2022)Background: The kynurenine pathway (KP) has been identified as a potential mediator linking acute illness to cognitive dysfunction by generating neuroactive metabolites in response to inflammation. Delirium (acute confusion) ... -
“The challenge is the complexity” – A qualitative study about decision-making in advanced lung cancer treatment
(Journal article; Peer reviewed, 2023)Introduction The value of shared decision-making and decision aids (DA) has been well documented yet remain difficult to integrate into clinical practice. We wanted to investigate needs and challenges regarding ... -
Challenges in diagnosing paediatric malaria in Dar es Salaam, Tanzania
(Peer reviewed; Journal article, 2013-07-03)Background: Malaria is a major cause of paediatric morbidity and mortality. As no clinical features clearly differentiate malaria from other febrile illnesses, and malaria diagnosis is challenged by often lacking laboratory ... -
Challenges in diagnosing pediatric malaria in Dar es Salaam, Tanzania
(Conference poster, 2012-10-15) -
The Challenges of Vaccine Trial Participation among Underserved and Hard-to-Reach Communities: An Internal Expert Consultation of the VACCELERATE Consortium
(Journal article; Peer reviewed, 2023)Underserved and hard-to-reach population groups are under-represented in vaccine trials. Thus, we aimed to identify the challenges of vaccine trial participation of these groups in member countries of the VACCELERATE ... -
Change in pulmonary diffusion capacity in a general population sample over 9 years
(Peer reviewed; Journal article, 2016-09-02)Rationale: Data on the change in diffusion capacity of the lung for carbon monoxide (DLCO) over time are limited. We aimed to examine change in DLCO (ΔDLCO) over a 9-year period and its predictors. Methods: A Norwegian ... -
Change in pulmonary diffusion capacity in a general population sample over 9 years
(Peer reviewed; Journal article, 2016-09-02)Rationale: Data on the change in diffusion capacity of the lung for carbon monoxide (DL_CO) over time are limited. We aimed to examine change in DL_CO (ΔDL_CO) over a 9-year period and its predictors. Methods: A Norwegian ... -
Changes in cardiopulmonary exercise capacity and limitations 3 to 12 months after COVID-19
(Journal article; Peer reviewed, 2023)Rationale: To describe cardiopulmonary function during exercise 12 months after hospital discharge for coronavirus disease 2019 (COVID-19), assess the change from 3 to 12 months, and compare the results with matched controls ... -
Changes in eicosapentaenoic acid and docosahexaenoic acid and risk of cardiovascular events and atrial fibrillation: A secondary analysis of the OMEMI trial
(Journal article; Peer reviewed, 2022)Background The cardiovascular benefit from n-3 polyunsaturated fatty acids (PUFAs) after acute myocardial infarction (AMI) is controversial, and the importance of serum eicosapentaenoic acid (EPA) and docosahexaenoic acid ... -
Changes in Gait symmetry, Gait velocity and self-reported function following total hip replacement
(Peer reviewed; Journal article, 2011-09)Objective: To investigate the magnitude of change at different time points in measures of gait symmetry, gait velocity and self-reported function following total hip replacement. Design: Longitudinal with test occasions ... -
Changes in heart rate from 5 s to 5 min after birth in vaginally delivered term newborns with delayed cord clamping
(Journal article; Peer reviewed, 2021)Objective: To determine heart rate centiles during the first 5 min after birth in healthy term newborns delivered vaginally with delayed cord clamping. Design: Single-centre prospective observational study. Setting: ... -
Changes in Infection Prevention Practices and Occurrence of Skin Symptoms among Healthcare Workers, Cleaners and Day-care Workers in Norway during the COVID-19 Pandemic
(Journal article; Peer reviewed, 2023)The COVID-19 pandemic has resulted in increased attention on infection prevention measures. This study aims to assess whether changes in hand hygiene procedures, use of personal protective equipment and moisturizers during ... -
Changes in lipoprotein particle subclasses, standard lipids, and apolipoproteins after supplementation with n-3 or n-6 PUFAs in abdominal obesity: A randomized double-blind crossover study
(Journal article; Peer reviewed, 2021)Background & aims Marine-derived omega-3 (n-3) polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), lower circulating levels of triacylglycerols (TAGs), and the plant-derived ... -
Changes in mental health symptoms from April (COVID-19 outbreak) to December 2020 in Norway: A two-wave study
(Journal article; Peer reviewed, 2023)The main objective of the study was to investigate changes in mental health symptoms from the start of the pandemic in Norway (April) to December 2020. A total of 6017 participants completed an assessment of the survey at ...