Browsing Faculty of Medicine by Title
Now showing items 7990-8009 of 8754
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T cell receptor assessment in autoimmune disease requires access to the most adjacent immunologically active organ
(Peer reviewed; Journal article, 2017-07)Next generation sequencing of T and B cell receptors is emerging as a valuable and effective method to diagnose and monitor hematopoietic malignancies. So far, this approach has not been fully explored in regard to autoimmune ... -
T Cell Responses and Regulation and the Impact of In Vitro IL-10 and TGF-beta Modulation During Treatment of Active Tuberculosis
(Peer reviewed; Journal article, 2017-02)Mycobacterium tuberculosis (Mtb) is particularly challenging for the immune system being an intracellular pathogen, and a variety of T cell subpopulations are activated by the host defence mechanism. In this study, we ... -
Tablettknusing i eldreomsorgen, sett fra et legemiddelteknologisk perspektiv
(Master thesis, 2011-05-19)Bakgrunn: Vi blir stadig eldre og med økende alder følger også økt morbiditet og dermed også medisinbruk. Mange eldre bor i omsorgsboliger og får tildelt medisiner av helsepersonell. Ofte kan det av ulike grunner være behov ... -
Tailoring NIV by dynamic laryngoscopy in a child with spinal muscular atrophy type I
(Journal article; Peer reviewed, 2021)Dynamic laryngoscopy during noninvasive (NIV) respiratory therapy is feasible and may facilitate optimal and individualized treatment in patients with chronic respiratory failure, also in children. -
TAKROLIMUS -Farmakokinetikk i tidlig fase etter levertransplantasjon
(Master thesis, 2009-05-20)Takrolimus er del av standard immunsuppresjon og vedlikeholdsdoseringsregimet etter levertransplantasjon. Det har et smalt terapeutisk vindu, og monitorers derfor etter bunnkonsentrasjonsmålinger. Intra- og interindividuelle ... -
Taktile intervensjoner hos pasienter med langvarig korsryggsmerte En scoping review
(Master thesis, 2022-11-18)Bakgrunn: Prevalensen av langvarige korsryggsmerter er i Norge svært høy og denne tilstanden er den vanligste årsaken til sykdomsbyrde. I lys av en biopsykososial modell er forståelsen for de mekanistiske nevrofysiologiske ... -
TAM-reseptoruttrykk i labiale spyttkjertler hos pasienter med primært Sjögrens syndrom
(Master thesis, 2023-05-22)Hensikt: Studien sammenlignet TAM-reseptoruttrykk i labiale spyttkjertler mellom pasienter med primært Sjögrens syndrom og kontroller med sicca symptomer for å identifisere potensiell svekkelse av apoptotisk cellefjerning ... -
Tamoxifen in the treatment of luminal breast cancer. Implications of active metabolites on gene expression, side effects and clinical outcome
(Doctoral thesis, 2019-02-21)Estrogen is a driver for the development and progression of luminal breast cancer, and up to 80% of all breast cancers diagnosed belong to the luminal subtype. The estrogenic effect on breast tumors can be reduced by the ... -
Tannhelsepersonell i den offentlige tannhelsetjenesten i Norge sine kunnskaper, utfordringer og erfaringer med pasienter med leppe-kjeve og ganespalte
(Master thesis, 2021-03-01)Orale spalter er den mest hyppige forekommende kategori av fødselsdefekter i hode-hals-området. Bakgrunnen for denne studien var å kartlegge tannhelsepersonell i Norge sine erfaringer, utfordringer og kunnskap om pasienter ... -
Tannhelsepersonell utsettes for risiko forbundet med materialbruk
(Master thesis, 2021-03-01)Bakgrunn. Tannhelsepersonell utsettes daglig for ulike typer eksponeringer, som kan påvirke helsen negativt. Derfor er det viktig å opprettholde gode arbeidsrutiner og ha kunnskap om materialene en bruker, slik at en kan ... -
Tannspor. Tidsbestemmelse og betydning i rettslig sammenheng
(Master thesis, 2013-01-24)Background: A bitemark can be defined as an injury on the skin or an object, caused by the tooth surfaces of a human or animal. Both loss of epithelium (abrasion) and bruising (haematoma) on skin can be seen after a bitemark ... -
Tannutviklingsforstyrrelser i det permanente tannsett som følge av kjemoterapi og strålebehandling
(Master thesis, 2009-04-27)Flere potensielt dødelige sykdommer og syndromer kan behandles med kjemoterapi og strålebehandling. Etter hvert som behandlingsopplegget for disse pasientene blir bedre øker også langtidsoverlevelsen og dermed også grunnlaget ... -
Tanzania national survey on iodine deficiency: impact after twelve years of salt iodation
(Peer reviewed; Journal article, 2009-09-03)Background: In many low-income countries, children are at high risk of iodine deficiency disorders, including brain damage. In the early 1990s, Tanzania, a country that previously suffered from moderate to severe iodine ... -
Target Values and Daytime Variation of Bone Turnover Markers in Monitoring Osteoporosis Treatment After Fractures
(Journal article; Peer reviewed, 2022)The serum bone turnover markers (BTM) procollagen type 1 N-terminal propeptide (P1NP) and C-terminal cross-linking telopeptide of type 1 collagen (CTX) are recommended for monitoring adherence and response of antiresorptive ... -
Target weight gain for moderately wasted children during supplementation interventions – a population-based approach
(Peer reviewed; Journal article, 2011-12)Objective: In malnourished populations, the weight-for-height Z-score (WHZ) distribution is shifted to the left. The aim of nutrition interventions should be to restore a normal WHZ distribution for the whole population. ... -
Targeted Next-Generation Sequencing of Cancer-Related Genes in a Norwegian Patient Cohort With Head and Neck Squamous Cell Carcinoma Reveals Novel Actionable Mutations and Correlations With Pathological Parameters
(Journal article; Peer reviewed, 2021)Background: Targeted next-generation sequencing (NGS) is increasingly applied in clinical oncology to advance personalized treatment. Despite success in many other tumour types, use of targeted NGS panels for assisting ... -
Targeted proteomics in a population-based study identifies serum PECAM-1 and TRIM21 as inflammation markers for periodontitis
(Journal article; Peer reviewed, 2023)Objectives Periodontitis (PD) can cause systematic inflammation and is associated with various metabolic processes in the body. However, robust serum markers for these relationships are still lacking. This study aims ... -
Targeted temperature management in cardiac arrest: survival evaluated by propensity score matching
(Peer reviewed; Journal article, 2017)Background: Targeted temperature management in cardiac arrest was introduced following evidence of increased survival from two controlled trials published in 2002. We wanted to investigate whether the introduction of ... -
Targeting APLN/APLNR improves antiangiogenic efficiency and blunts proinvasive side effects of VEGFA/VEGFR2 blockade in glioblastoma
(Peer reviewed; Journal article, 2019)Antiangiogenic therapy of glioblastoma (GBM) with bevacizumab, a VEGFA-blocking antibody, may accelerate tumor cell invasion and induce alternative angiogenic pathways. Here we investigate the roles of the proangiogenic ...