• Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence 

    Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco M.; Rustad, Even Holth; Sanders, Mathijs A.; Rye, Morten Beck; Sponaas, Anne-Marit; van der Holt, Bronno; Zweegman, Sonja; Hovig, Eivind; Meza, Leonardo Zepeda; Sundan, Anders; Myklebost, Ola; Sonneveld, Pieter; Waage, Anders (Journal article; Peer reviewed, 2022)
    We investigated genomic and transcriptomic changes in paired tumor samples of 29 in-house multiple myeloma (MM) patients and 28 patients from the MMRF CoMMpass study before and after treatment. A change in clonal composition ...
  • Radiation induced brain necrosis after proton therapy for head and neck cancer 

    Engeseth, Grete May (Doctoral thesis, 2022-12-09)
    Protonterapi gir reduksjon i normalvevsdoser sammenlignet med strålebehandling med fotoner, og det er antatt at dette vil resultere i en lavere forekomst av stråleinduserte seinskader. For å kompensere for en økt biologisk ...
  • Stable Southern Hemisphere westerly winds throughout the Holocene until intensification in the last two millennia 

    van der Bilt, Willem Godert Maria; D’Andrea, William J.; Oppedal, Lea Toska; Bakke, Jostein; Bjune, Anne Elisabeth; Zwier, Maaike (Journal article; Peer reviewed, 2022)
    The Southern Hemisphere westerly winds sustain the Southern Ocean’s role as one of Earth’s main carbon sinks, and have helped sequester nearly half the anthropogenic CO2 stored in the ocean. Observations show shifts in the ...
  • Prematur ovarialinsuffisiens 

    Vogt, Elinor Margrethe Chelsom; Russell, Hannah Ni Bhriain; Øksnes, Marianne; Lund, Agnethe (Journal article; Peer reviewed, 2022)
    Prematur ovarialinsuffisiens defineres som tap av ovariefunksjon før 40 års alder og er en kompleks tilstand med heterogen etiologi. Tidlig diagnose og igangsetting av hormonerstattende behandling er viktig for å lindre ...
  • Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes 

    Fedotkina, Olena; Jain, Ruchi; Prasad, Rashmi B.; Luk, Andrea; García-Ramírez, Marta; Özgümüs, Türküler; Cherviakova, Liubov; Khalimon, Nadiya; Svietleisha, Tetiana; Buldenko, Tetiana; Kravchenko, Victor; Jain, Deepak; Vaag, Allan; Chan, Juliana; Khalangot, Mykola D.; Hernández, Cristina; Nilsson, Peter M.; Simo, Rafael; Artner, Isabella; Lyssenko, Valeriya (Journal article; Peer reviewed, 2022-05-05)
    Persons with type 2 diabetes born in the regions of famine exposures have disproportionally elevated risk of vision-threatening proliferative diabetic retinopathy (PDR) in adulthood. However, the underlying mechanisms are ...

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