Browsing Department of Clinical Science by Title
Now showing items 823-842 of 2341
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Food hypersensitivity: an examination of factors influencing symptoms and temporal changes in the prevalence of sensitization in an adult sample
(Journal article; Peer reviewed, 2023)Background/Objectives: Food hypersensitivity (FHS) is common, but little is known about the factors associated with severe reactions, age of onset and whether sensitization persists. This study examines the factors associated ... -
Food Sources Contributing to Intake of Choline and Individual Choline Forms in a Norwegian Cohort of Patients With Stable Angina Pectoris
(Journal article; Peer reviewed, 2021)Background: Choline is an essential nutrient involved in a wide range of physiological functions. It occurs in water- and lipid-soluble forms in the body and diet. Foods with a known high choline content are eggs, beef, ... -
Forekomst og håndtering av legemiddelinteraksjoner med warfarin ved Sykehuset Buskerud
(Master thesis, 2010-06-21)Denne studien kartlegger forekomsten av legemiddelinteraksjoner med warfarin hos 105 pasienter skrevet ut fra seks sengeposter ved medisinsk klinikk, kirurgisk klinikk og nevromuskulær klinikk ved Sykehuset Buskerud. ... -
Formulering av kortisonpreparat til bruk ved binyrebarksvikt
(Master thesis, 2008-06-01) -
Forskningsveiledning - en av de essensielle faktorene på «veien til doktorgrad»
(Peer reviewed; Journal article, 2013)The journey to finish a PhD thesis is a long race, and several factors may play important roles in this process. A good working relationship between the supervisor and the candidate is an essential component for achieving ... -
Forskrivningspraksis av psykofarmaka i barne- og ungdomspsykiatri
(Master thesis, 2021-05-20)Bakgrunn: Riktig legemiddelbruk hos barn og unge er et viktig innsatsområde for å styrke kvalitet av behandling og pasientsikkerhet. Forskrivning av medikamenter til barn og unge er et utfordrende terapiområde i barne- og ... -
Fotokjemisk internalisering (PCI) av HER2-rettet immunotoksin; trastuzumab-saporin
(Master thesis, 2009-05-19)En begrensning for terapeutisk nytte av makromolekyler som utøver sin effekt intracellulært er at de etter opptak ved endocytose degraderes lysosomalt før de når sitt terapeutiske mål i cytosol. Fotokjemisk internalisering ... -
Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer’s Disease
(Peer reviewed; Journal article, 2019)Introduction: The aim of the study is to describe the frequency of frailty in people with a new diagnosis of mild dementia due to Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). Methods: This is a secondary ... -
The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy Indian adolescents
(Peer reviewed; Journal article, 2014-07-03)Background: QuantiFERON-TB Gold In-Tube (QFT) is an IFNγ-release assay used in the diagnosis of Mycobacterium tuberculosis (MTB) infection. The risk of TB progression increases with the magnitude of the MTB-specific ... -
Frequency and prognostic implications of orthostatic hypotension and white matter hyperintensities in older people with mild dementia
(Doctoral thesis, 2014-09-19)Background: In addition to cognitive impairments, dementia sufferers may have other problems as well, such as depression and orthostatic hypotension (OH), both of which according to previous studies may be associated with ... -
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
(Peer reviewed; Journal article, 2015)Mitochondrial genomes are separated from the nuclear genome for most of the cell cycle by the nuclear double membrane, intervening cytoplasm, and the mitochondrial double membrane. Despite these physical barriers, we show ... -
Friedreich ataxia in Norway - An epidemiological, molecular and clinical study Rare neurological diseases
(Peer reviewed; Journal article, 2015-09-04)Background: Friedreich ataxia is an autosomal recessive hereditary spinocerebellar disorder, characterized by progressive limb and gait ataxia due to proprioceptive loss, often complicated by cardiomyopathy, diabetes and ... -
Fucosylated AGP glycopeptides as biomarkers of HNF1A-Maturity onset diabetes of the young
(Journal article; Peer reviewed, 2022)Aims: We previously demonstrated that antennary fucosylated N-glycans on plasma proteins are regulated by HNF1A and can identify cases of Maturity-Onset Diabetes of the Young caused by HNF1A variants (HNF1A-MODY). Based ... -
Fueling the flames of colon cancer – does CRP play a direct pro-inflammatory role?
(Journal article; Peer reviewed, 2023-03-17)Background: Systemic inflammation, diagnostically ascribed by measuring serum levels of the acute phase reactant C-reactive protein (CRP), has consistently been correlated with poor outcomes across cancer types. CRP exists ... -
Function and regulation of Steroid Receptor Coactivator 2. Transcriptional regulation of cellular metabolism
(Doctoral thesis, 2015-12-18)Nuclear hormone receptors (NRs) associate with coregulators to enable complex programs of gene expression. The p160 steroid receptor coactivator 2 (SRC- 2/GRIP1) regulates metabolism and cellular processes in a tissue-specific ... -
Functional analyses of BRCA1 variants of unknown significance found in hereditary breast or ovarian cancer families in Norway: A tool for improved diagnosis
(Doctoral thesis, 2023-03-21)Tumorsuppressorgenet BRCA1 speler mange viktige roller for å hindre tumorutvikling, og endringar i BRCA1-genet er ei av hovudårsakene til arveleg bryst- og eggstokk-kreft (HBOC). I artikkel I vart det laga ei oversikt over ... -
Functional Analyses of Rare Germline Missense BRCA1 Variants Located within and outside Protein Domains with Known Functions
(Journal article; Peer reviewed, 2023-01-19)The BRCA1 protein is implicated in numerous important cellular processes to prevent genomic instability and tumorigenesis, and pathogenic germline variants predispose carriers to hereditary breast and ovarian cancer (HBOC). ... -
Functional analysis of tilS homologues in Bacteria and Archaea
(Master thesis, 2005-09-09)Out of all of the microorganisms sequenced so far about one third of the genes have unknown function. Several studies have shown that information on evolutionary relationships between unknown genes can aid in the prediction ... -
Functional and Binding H1N1pdm09-Specific Antibody Responses in Occasionally and Repeatedly Vaccinated Healthcare Workers: A Five-Year Study (2009-2014)
(Journal article; Peer reviewed, 2021)Background: In 2009, a novel influenza A/H1N1pdm09 emerged and caused a pandemic. This strain continued to circulate and was therefore included in the seasonal vaccines up to the 2016/2017-season. This provided a unique ... -
Functional characterization of genetic risk factors in autoimmune Addison’s disease
(Doctoral thesis, 2020-10-23)Autoimmune diseases occur when the immune system attacks and damages the body’s own tissue. Why people develop these diseases, and how the autoimmune reaction develops are unanswered questions. Autoimmune Addison's disease ...