Blar i Department of Clinical Science på tittel
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Global Lung Function Initiative 2012 reference equations for spirometry in the Norwegian Population
(Peer reviewed; Journal article, 2016)We studied the fit of the Global Lung Function Initiative (GLI) all-age reference values to Norwegians, compared them with currently used references (European Community for Steel and Coal (ECSC) and Zapletal) and estimated ... -
Glucocorticoid pharmacogenetics in Addison's disease - The role of the immunophilin FK506-binding protein (FKBP51) for glucocorticoid sensitivity
(Master thesis, 2008-05-31)There is great variation in the inter-individual sensitivity to glucocorticoids. The immunophilin FK506 binding protein (FKBP51) confers short-loop negative feedback inhibition of the glucocorticoid signalling pathway. ... -
Glucocorticoid Treatment and Quality of Life in Addison’s disease
(Doctoral thesis, 2014-06-06)Addison’s disease (AD) is rare and result in lack of the adrenal hormones cortisol, aldosterone and adrenal androgens. Despite conventional oral replacement therapy, mortality is increased and Health-Related Quality-of-life ... -
Glycated albumin and continuous glucose monitoring metrics across pregnancy in women with pre-gestational diabetes
(Journal article; Peer reviewed, 2022)Introduction: Glycated albumin (GA), a biomarker reflecting short-term glycaemia, may be useful to assess glycaemic control in pregnancy. We examined the association between GA and continuous glucose monitoring (CGM) metrics ... -
Glycated albumin in pregnancy: LC-MS/MS-based reference interval in healthy, nulliparous Scandinavian women and its diagnostic accuracy in gestational diabetes mellitus
(Journal article; Peer reviewed, 2022)Glycated albumin (GA) may be a useful biomarker of glycemia in pregnancy. The aim of this study was to establish the reference interval (RI) for GA, analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS), ... -
Glycated hemoglobin and long-term prognosis in patients with suspected stable angina pectoris without diabetes mellitus: A prospective cohort study
(Peer reviewed; Journal article, 2015-05)Objective: Associations of glycated hemoglobin A1c (HbA1c) levels to incident coronary and cardiovascular events among non-diabetic patients with coronary artery disease are unclear. We investigated relations of HbA1c to ... -
GM-CSF, Flt3-L and IL-4 affect viability and function of conventional dendritic cell types 1 and 2
(Journal article; Peer reviewed, 2023-01-12)Conventional type 1 dendritic cells (cDC1) and conventional type 2 dendritic cells (cDC2) have attracted increasing attention as alternatives to monocyte-derived dendritic cells (moDCs) in cancer immunotherapy. Use of cDCs ... -
GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis
(Peer reviewed; Journal article, 2018-12-06)Autoantibodies have been associated with autoimmune diseases. However, studies have identified autoantibodies in healthy donors (HD) who do not develop autoimmune disorders. Here we provide evidence of a network of ... -
Grading of Aortic Stenosis: Is it More Complicated in Women?
(Journal article; Peer reviewed, 2022)Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and ... -
Granulocyte colony-stimulating factor alters the systemic metabolomic profile in healthy donors
(Journal article; Peer reviewed, 2017)Introduction: Peripheral blood stem cells mobilized by granulocyte colony-stimulating factor (G-CSF) from healthy donors are commonly used for allogeneic stem cell transplantation. The effect of G-CSF administration on ... -
Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish
(Journal article; Peer reviewed, 2022)Graphene is an attractive choice for the development of an effective drug carrier in cancer treatment due to its high adsorption area and pH-responsive drug affinity. In combination with the highly potent metabolic drug ... -
Grip strength in men and women aged 50–79 years is associated with non-vertebral osteoporotic fracture during 15 years follow-up: The Tromsø Study 1994–1995
(Peer reviewed; Journal article, 2020)In 50–79-year-olds who participated in the Tromsø Study (1994–1995), the risk of non-vertebral osteoporotic fractures during 15 years follow-up increased by 22% in men and 9% in women per 1 SD lower grip strength. The ... -
Growing with dinosaurs: natural products from the Cretaceous relict Metasequoia glyptostroboides Hu & Cheng - a molecular reservoir from the ancient world with potential in modern medicine
(Peer reviewed; Journal article, 2015-02-22)After the sensational rediscovery of living exemplars of the Cretaceous relict Metasequoia glyptostroboides—a tree previously known exclusively from fossils from various locations in the northern hemisphere, there has been ... -
Growth dynamics of the vestibular schwannoma
(Doctoral thesis, 2012-04-12)Introduction: Studies concerning vestibular schwannoma (VS) are inconsistent in reporting of tumor size and growth. This means that results found in one paper using one set of definitions cannot be compared directly with ... -
Growth of glioblastoma xenografts in the brains of NOD/SCID mice following administration of a demyelinating agent
(Master thesis, 2011-06-16)Background: Glioblastoma multiforme (GBM) is an incurable and fatal brain cancer with short median survival. Due to the infiltrative growth into the surrounding brain parenchyma, radical surgery is not possible and their ... -
Guideline-Recommended Time Less Than 90 Minutes From ECG to Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Is Associated with Major Survival Benefits, Especially in Octogenarians: A Contemporary Report in 11 226 Patients from NORIC
(Journal article; Peer reviewed, 2022)Background Using contemporary data from NORIC (Norwegian Registry of Invasive Cardiology) we investigated the predictive value of patient age and time from ECG diagnosis to sheath insertion (ECG‐2‐sheath) in primary ... -
Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19
(Journal article; Peer reviewed, 2023)Background Gut microbiota alterations have been reported in hospitalized COVID-19 patients, with reduced alpha diversity and altered microbiota composition related to respiratory failure. However, data regarding gut ... -
Gut microbiota-dependent trimethylamine N-oxide associates with inflammation in common variable immunodeficiency
(Journal article; Peer reviewed, 2020)A substantial proportion of patients with common variable immunodeficiency (CVID) have inflammatory and autoimmune complications of unknown etiology. We have previously shown that systemic inflammation in CVID correlates ... -
GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility
(Journal article; Peer reviewed, 2021)Autoimmune Addison’s disease (AAD) is characterized by the autoimmune destruction of the adrenal cortex. Low prevalence and complex inheritance have long hindered successful genetic studies. We here report the first ... -
GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores
(Journal article; Peer reviewed, 2019)Objective: More than 90% of people who attempt suicide have a psychiatric diagnosis; however, twin and family studies suggest that the genetic etiology of suicide attempt is partially distinct from that of the psychiatric ...