Blar i Department of Clinical Science på tittel
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Diagnosing pediatric malaria in Dar es Salaam, Tanzania. Clinical and laboratorial perspectives
(Doctoral thesis, 2014-05-20)Malaria is an extensive global health issue with high morbidity and mortality. Diagnostics of malaria are challenging. Clinically malaria is indistinguishable from various other infectious diseases. Microscopy of blood ... -
Diagnosis and follow-up of treatment of latent tuberculosis; the utility of the QuantiFERON-TB Gold In-tube assay in outpatients from a tuberculosis low-endemic country
(Peer reviewed; Journal article, 2010-03-08)Background Interferon-gamma (IFN-γ) Release Assays (IGRA) are more specific than the tuberculosis skin test (TST) in the diagnosis of latent tuberculosis (TB) infection (LTBI). We present the performance of the QuantiFERON®-TB ... -
Diagnostic accuracy of liquid biopsy in endometrial cancer
(Journal article; Peer reviewed, 2021)Background: Liquid biopsy is a minimally invasive collection of a patient body fluid sample. In oncology, they offer several advantages compared to traditional tissue biopsies. However, the potential of this method in ... -
Diagnostic stewardship aiming at expectorated or induced sputum promotes microbial diagnosis in community-acquired pneumonia
(Journal article; Peer reviewed, 2022)Purpose: Studies on aetiology of community-acquired pneumonia (CAP) vary in terms of microbial sampling methods, anatomical locations, and laboratory analyses, since no gold standard exists. In this large, multicentre, ... -
Diagnostic testing of autonomous cortisol secretion in adrenal incidentalomas
(Journal article; Peer reviewed, 2020)Objective: Autonomous cortisol secretion (ACS) is a condition with ACTH-independent cortisol overproduction from adrenal incidentalomas (AI) or adrenal hyperplasia. The hypercortisolism is often mild, and most patients ... -
Diagnostic validity of fatal cerebral strokes and coronary deaths
(Peer reviewed; Journal article, 2011-03)Mortality statistics represent important endpoints in epidemiological studies. The diagnostic validity of cerebral stroke and ischemic heart disease recorded as the underlying cause of death in Norwegian mortality statistics ... -
Diagnostikk og behandling av autoimmun hepatitt
(Journal article; Peer reviewed, 2021)Autoimmun hepatitt er en kronisk leversykdom som ubehandlet kan føre til levercirrhose og leversvikt. Majoriteten av pasientene responderer godt på standard immunsuppressiv behandling, men noen opplever bivirkninger eller ... -
Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat
(Peer reviewed; Journal article, 2014-05-27)Aim: Chemotherapy with doxorubicin is limited by cardiotoxicity. Free radical generation and mitochondrial dysfunction are thought to contribute to doxorubicin-induced cardiac failure. In this study we wanted to investigate ... -
Diet and effects of diet management on symptoms and quality of life in patients with irritable bowel syndrome
(Master thesis, 2011-05-16)Background: Irritable bowel syndrome (IBS) is a gastrointestinal disorder manifested by abdominal discomfort or pain, bloating and abdominal distension, and changes in the defecation pattern between diarrhoea and constipation. ... -
Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study
(Peer reviewed; Journal article, 2013-10-08)Background: A beneficial effect of a high n-3 long-chain polyunsaturated fatty acid (LCPUFA) intake has been observed in heart failure patients, who are frequently insulin resistant. We investigated the potential influence ... -
Dietary linoleic acid induces obesity through excessive endocannabinoid activity
(Doctoral thesis, 2012-03-23)Background: Dietary intakes of the n-6 fatty acid linoleic acid (LA, 18:2n-6) have increased dramatically during the 20th century. Replacing fish oil (FO) with vegetable oil (VO) in feed for farmed fish introduces LA and ... -
Dietary predictors of bone mineral density, hip fractures, mobility and muscle strength - in community-dwelling older persons
(Doctoral thesis, 2018-10-23)Background: The aging process involves decline of both muscle and bone mass. The loss of muscle mass is associated with decreased muscle strength and mobility, while loss of bone mass leads to osteoporosis and increased ... -
Dietary RNA (s. Cerevisiae) stimulated cytokine secretion in human immune cells: involvement of p38 MAPK, and co-stimulation with LPS or PHA
(Master thesis, 2009-07-01)Dietary nucleotides and nucleic acids are known to affect immune functions in animals and humans, both in vitro and in vivo. In this thesis I wanted to investigate the effect of dietary RNA from baker’s yeast on cytokine ... -
Diets differing in carbohydrate cellularity and amount similarly reduced visceral fat in people with obesity - a randomized controlled trial (CARBFUNC)
(Journal article; Peer reviewed, 2022)Background & aims: Visceral adipose tissue (VAT) volume is associated with common lifestyle diseases. Dietary quality, including food matrix and degree of carbohydrate cellularity, as well as the carbohydrate/fat ratio, ... -
Differences in lung function, bronchial hyperresponsiveness and respiratory health between elite athletes competing in different sports
(Journal article; Peer reviewed, 2022)The aim of this study was to examine lung function, bronchial hyperresponsiveness (BHR) and exercise-induced respiratory symptoms in elite athletes performing different sports. Norwegian national-team athletes (30 swimmers, ... -
Differences in metastatic patterns in relation to time between primary surgery and first relapse from breast cancer suggest synchronized growth of dormant micrometastases
(Peer reviewed; Journal article, 2014-08)A significant variation in the metastatic pattern among breast cancer patients exists. Clinical observations suggest that these differences are related to time to recurrence (TTR), thus suggesting a common systemic growth ... -
Differences in white blood cell proportions between schizophrenia cases and controls are influenced by medication and variations in time of day
(Journal article; Peer reviewed, 2023)Cases with schizophrenia (SCZ) and healthy controls show differences in white blood cell (WBC) counts and blood inflammation markers. Here, we investigate whether time of blood draw and treatment with psychiatric medications ... -
Different adipose tissue development in mice pair fed fish oil and different carbohydrates
(Master thesis, 2011-05-16)Obesity causes several health problems, including insulin resistance, Type 2 diabetes, heart diseases, disrupted energy metabolism and low-grade inflammation. Being obese increases the risk of getting metabolic syndrome. ... -
Different skeletal effects of the peroxisome proliferator activated receptor (PPAR)alpha agonist fenofibrate and the PPAR gamma agonist pioglitazone
(Peer reviewed; Journal article, 2009-03-30)Background: All the peroxisome proliferator activated receptors (PPARs) are found to be expressed in bone cells. The PPARγ agonist rosiglitazone has been shown to decrease bone mass in mice and thiazolidinediones (TZDs) ... -
Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation
(Journal article; Peer reviewed, 2020)Background Myeloid-derived suppressor cells (MDSC) are a functional myeloid cell subset that includes myeloid cells with immune suppressive properties. The presence of MDSC has been reported in the peripheral blood of ...