Blar i Department of Clinical Science på tittel

Viser treff 698-717 av 2295

    • Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults 

      Zahed, Hana; Johansson, Mattias; Ueland, Per Magne; Midttun, Øivind; Milne, Roger L.; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Grankvist, Kjell; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loic; Wilkens, Lynne R.; Weinstein, Stephanie J.; Albanes, Demetrius; Cai, Qiuyin; Blot, William J.; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Muller, David; Brennan, Paul; Guida, Florence; Robbins, Hilary A. (Journal article; Peer reviewed, 2021)
      Imbalances of blood biomarkers are associated with disease, and biomarkers may also vary non-pathologically across population groups. We described variation in concentrations of biomarkers of one-carbon metabolism, vitamin ...

    • Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer 

      Shen, Hui; Fridley, BL; Song, HL; Lawrenson, K; Cunningham, JM; Ramus, SJ; Cicek, MS; Tyrer, J; Stram, D; Larson, MC; Kobel, M; Ziogas, A; Zheng, W; Yang, HP; Wu, AH; Wozniak, EL; Woo, YL; Winterhoff, B; Wik, Elisabeth; Whittemore, AS; Wentzensen, N; Weber, RP; Vitonis, AF; Vincent, D; Vierkant, RA; Vergote, I; Van Den Berg, D; Van Altena, AM; Tworoger, SS; Thompson, PJ; Tessier, DC; Terry, KL; Teo, SH; Templeman, C; Stram, DO; Southey, MC; Sieh, W; Siddiqui, N; Shvetsov, YB; Shu, XO; Shridhar, V; Wang-Gohrke, S; Severi, G; Schwaab, I; Salvesen, Helga Birgitte; Rzepecka, IK; Runnebaum, IB; Rossing, MA; Rodriguez-Rodriguez, L; Risch, HA; Renner, SP; Poole, EM; Pike, MC; Phelan, CM; Pelttari, LM; Pejovic, T; Paul, J; Orlow, I; Omar, SZ; Olson, SH; Odunsi, K; Nickels, S; Nevanlinna, H; Ness, RB; Narod, SA; Nakanishi, T; Moysich, KB; Monteiro, ANA; Moes-Sosnowska, J; Modugno, F; Menon, U; McLaughlin, JR; McGuire, V; Matsuo, K; Adenan, NAM; Massuger, LFAG; Lurie, G; Lundvall, L; Lubinski, J; Lissowska, J; Levine, DA; Leminen, A; Lee, AW; Le, ND; Lambrechts, S; Lambrechts, D; Kupryjanczyk, J; Krakstad, Camilla; Konecny, GE; Kjaer, SK; Kiemeney, LA; Kelemen, LE; Keeney, GL; Karlan, BY; Karevan, R; Kalli, KR; Kajiyama, H; Ji, BT; Jensen, A; Jakubowska, A; Iversen, E; Hosono, S; Hogdall, CK; Hogdall, E; Hoatlin, M; Hillemanns, P; Heitz, F; Hein, R; Harter, P; Halle, Mari Kyllesø; Hall, P; Gronwald, J; Gore, M; Goodman, MT; Giles, GG; Gentry-Maharaj, A; Garcia-Closas, M; Flanagan, JM; Fasching, PA; Ekici, AB; Edwards, R; Eccles, D; Easton, DF; Durst, M; du Bois, A; Dork, T; Doherty, JA; Despierre, E; Dansonka-Mieszkowska, A; Cybulski, C; Cramer, DW; Cook, LS; Chen, XQ; Charbonneau, B; Chang-Claude, J; Campbell, I; Butzow, R; Bunker, CH; Brueggmann, D; Brown, R; Brooks-Wilson, A; Brinton, LA; Bogdanova, N; Block, MS; Benjamin, E; Beesley, J; Beckmann, MW; Bandera, EV; Baglietto, L; Bacot, F; Armasu, SM; Antonenkova, N; Anton-Culver, H; Aben, KK; Liang, D; Wu, XF; Lu, KR; Hildebrandt, MAT; Schildkraut, JM; Sellers, TA; Huntsman, D; Berchuck, A; Chenevix-Trench, G; Gayther, SA; Pharoah, PDP; Laird, PW; Goode, EL; Pearce, CL (Peer reviewed; Journal article, 2013-03-27)
      HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this gene differentially associates with ...

    • An epigenetic association analysis of childhood trauma in psychosis reveals possible overlap with methylation changes associated with PTSD 

      Løkhammer, Solveig; Stavrum, Anne-Kristin Støbakk; Polushina, Tatiana; Aas, Monica; Ottesen, Akiah; Andreassen, Ole; Melle, Ingrid; Hellard, Stephanie Francoise Claire Le (Journal article; Peer reviewed, 2022)
      Patients with a severe mental disorder report significantly higher levels of childhood trauma (CT) than healthy individuals. Studies have suggested that CT may affect brain plasticity through epigenetic mechanisms and ...

    • Epigenome-wide association of father's smoking with offspring DNA methylation: a hypothesis-generating study 

      Knudsen, Gerd Toril Mørkve; Rezwan, FI; Johannessen, Ane; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Gomez Real, Francisco; Krauss-Etschmann, Susanne; Patil, Viswanath; Jarvis, Deborah; Arshad, SH; Holloway, John W; Svanes, Cecilie (Peer reviewed; Journal article, 2019)
      Epidemiological studies suggest that father’s smoking might influence their future children’s health, but few studies have addressed whether paternal line effects might be related to altered DNA methylation patterns in the ...

    • ERG and SIM2 transcription factors in prostate cancer – their role in carcinogenesis and potential clinical utility 

      Rostad, Kari (Doctoral thesis, 2011-01-27)

    • Escherichia marmotae—a Human Pathogen Easily Misidentified as Escherichia coli 

      Sivertsen, Audun; Dyrhovden, Ruben; Tellevik, Marit Gjerde; Bruvold, Torbjørn Sæle; Nybakken, Eirik Jovall; Skutlaberg, Dag Harald; Skarstein, Ingerid; Kommedal, Øyvind (Journal article; Peer reviewed, 2022)
      We hereby present the first descriptions of human-invasive infections caused by Escherichia marmotae, a recently described species that encompasses the former “Escherichia cryptic clade V.” We describe four cases, one acute ...

    • Estimating cardiac output from coronary CT angiography: an individualized compartment model in comparison to the Stewart–Hamilton method 

      Leiknes, Jon Bjarne; Hiorth, Aksel; Havnen, Jorunn; Greve, Ole Jacob; Kurz, Kathinka Dæhli; Larsen, Alf Inge (Journal article; Peer reviewed, 2023)
      Background: Attenuation is correlated with the concentration of contrast medium (CM) in the arteries. The cardiac output (CO) affects the concentration of CM in the circulatory system; therefore, CO affects the time–density ...

    • Estimating the within-subject (CVI) and between-subject (CVG) biological variation of serum tryptase 

      Skarbø, Birthe Rochlenge Skarbø; Vinnes, Erik Wilhelm; Wentzel-Larsen, Tore; Sylte, Marit Sverresdotter; Apelseth, Torunn Oveland (Journal article; Peer reviewed, 2021)
      Background Tryptase is used as a biomarker to support the diagnosis of anaphylaxis and hematologic diseases. In the event of a mast cell activation during anaphylaxis, a temporary increase in the concentration of tryptase ...

    • European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation 

      Budu-Aggrey, Ashley; Kilanowski, Anna; Sobczyk, Maria K.; Shringarpure, Suyash S.; Mitchell, Ruth; Reis, Kadri; Reigo, Anu; Mägi, Reedik; Nelis, Mari; Tanaka, Nao; Brumpton, Ben Michael; Thomas, Laurent Francois; Sole-Navais, Pol; Flatley, Christopher; Espuela-Ortiz, Antonio; Herrera-Luis, Esther; Lominchar, Jesus V. T.; Bork-Jensen, Jette; Marenholz, Ingo; Arnau-Soler, Aleix; Jeong, Ayoung; Fawcett, Katherine A.; Baurecht, Hansjorg; Rodriguez, Elke; Alves, Alexessander Couto; Kumar, Ashish; Sleiman, Patrick M.; Chang, Xiao; Medina-Gomez, Carolina; Hu, Chen; Xu, Cheng-jian; Qi, Cancan; El-Heis, Sarah; Titcombe, Philip; Antoun, Elie; Fadista, João; Wang, Carol A.; Thiering, Elisabeth; Wu, Baojun; Kress, Sara; Kothalawala, Dilini M.; Kadalayil, Latha; Duan, Jiasong; Zhang, Hongmei; Hadebe, Sabelo; Hoffmann, Thomas; Jorgenson, Eric; Choquet, Hélène; Risch, Neil; Njølstad, Pål Rasmus; Andreassen, Ole; Johansson, Stefan; Almqvist, Catarina; Gong, Tong; Ullemar, Vilhelmina; Karlsson, Robert; Magnusson, Patrik K. E.; Szwajda, Agnieszka; Burchard, Esteban G.; Thyssen, Jacob P.; Hansen, Torben; Kårhus, Line L.; Dantoft, Thomas M.; Jeanrenaud, Alexander C.S.N.; Ghauri, Ahla; Arnold, Andreas; Homuth, Georg; Lau, Susanne; Nöthen, Markus M.; Hübner, Norbert; Imboden, Medea; Visconti, Alessia; Falchi, Mario; Bataille, Veronique; Hysi, Pirro; Ballardini, Natalia; Boomsma, Dorret I.; Hottenga, Jouke J.; Müller-Nurasyid, Martina; Ahluwalia, Tarunveer S.; Stokholm, Jakob; Chawes, Bo; Schoos, Ann-Marie M.; Esplugues, Ana; Bustamante, Mariona; Raby, Benjamin; Arshad, Syed; German, Chris; Esko, Tõnu; Milani, Lili A.; Metspalu, Andres; Terao, Chikashi; Abuabara, Katrina; Løset, Mari; Hveem, Kristian; Jacobsson, Bo; Pino-Yanes, Maria; Strachan, David P.; Grarup, Niels; Linneberg, Allan; Lee, Young-Ae; Probst-Hensch, Nicole; Weidinger, Stephan; Jarvelin, Marjo-Riitta; Melén, Erik; Hakonarson, Hakon; Irvine, Alan D.; Jarvis, Deborah; Nijsten, Tamar; Duijts, Liesbeth; Vonk, Judith M.; Koppelmann, Gerard H.; Godfrey, Keith M.; Barton, Sheila J.; Feenstra, Bjarke; Pennell, Craig E.; Sly, Peter D.; Holt, Patrick G.; Williams, L. Keoki; Bisgaard, Hans; Bønnelykke, Klaus; Curtin, John; Simpson, Angela; Murray, Clare; Schikowski, Tamara; Bunyavanich, Supinda; Weiss, Scott T.; Holloway, John W.; Min, Josine L.; Brown, Sara J.; Standl, Marie; Paternoster, Lavinia (Journal article; Peer reviewed, 2023)
      Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery ...

    • The European Cardiac Resynchronization Therapy (CRT) Survey 

      Bogale, Nigussie (Doctoral thesis, 2011-10-20)
      Aims: The European Cardiac Resynchronization Therapy (CRT) Survey was a joint initiative taken by the Heart Failure (HFA) and the European Heart Rhythm (EHRA) Associations of the European Society of Cardiology (ESC) designed ...

    • European Neuroendocrine Tumor Society (ENETS) 2023 guidance paper for digestive neuroendocrine carcinoma 

      Sorbye, Halfdan; Grande, Enrique; Pavel, Marianne; Tesselaar, Margot; Fazio, Nicola; Reed, Nicholas Simon; Knigge, Ulrich; Christ, Emanuel; Ambrosini, Valentina; Couvelard, Anne; Tiensuu Janson, Eva (Journal article; Peer reviewed, 2023)
      This ENETS guidance paper, developed by a multidisciplinary working group, provides up-to-date and practical advice on the diagnosis and management of digestive neuroendocrine carcinoma, based on recent developments and ...

    • Evaluating national guidelines for monitoring early growth using routinely collected data in Bergen, Norway 

      Balthasar, Melissa Rajini; Roelants, Mathieu; Brannsether-Ellingsen, Bente; Stangenes, Kristine Marie; Magnus, Maria Christine; Håberg, Siri Eldevik; Øverland, Simon Nygaard; Juliusson, Pétur Benedikt (Journal article; Peer reviewed, 2023)
      Aims: The overarching aim of this study was to evaluate the Norwegian guidelines for growth monitoring using routinely collected data from healthy children up to five years of age. We analysed criteria for both status ...

    • Evaluating the suitability of the Low Energy Availability in Females Questionnaire (LEAF-Q) for female footballers 

      Dasa, Marcus Småvik; Friborg, Oddgeir; Kristoffersen, Morten; Pettersen, Gunn; Sagen, Jørn Vegard; Sundgot-Borgen, Jorunn; Rosenvinge, Jan H (Journal article; Peer reviewed, 2023)
      Background The Low Energy Availability in Females Questionnaire (LEAF-Q) is a screening tool developed to detect endurance athletes and dancers at risk for development of persistent low energy availability (LEA) and the ...

    • Evaluating Translational Methods for Personalized Medicine—A Scoping Review 

      Fosse, Vibeke Samuelsen; Oldoni, Emanuela; Gerardi, Chiara; Banzi, Rita; Fratelli, Maddalena; Bietrix, Florence; Ussi, Anton; Andreu, Antonio L.; McCormack, Emmet (Journal article; Peer reviewed, 2022)
      The introduction of personalized medicine, through the increasing multi-omics characterization of disease, brings new challenges to disease modeling. The scope of this review was a broad evaluation of the relevance, validity, ...

    • Evaluation of interferon-beta neutralizing antibodies in individual patients with multiple sclerosis based on phospho-specific flow cytometry 

      Gavasso, Sonia (Doctoral thesis, 2013-03-19)
      Background: Recombinant human interferon-beta (IFN-β) is the most frequently used drug for treating relapsing-remitting multiple sclerosis (RRMS), a demyelinating disease of the central nervous system. It modulates the ...

    • Evaluation of the Rosa Chatbot Providing Genetic Information to Patients at Risk of Hereditary Breast and Ovarian Cancer: Qualitative Interview Study 

      Siglen, Elen; Vetti, Hildegunn Høberg; Augestad, Mirjam Tonheim; Steen, Vidar Martin; Lunde, Åshild; Bjorvatn, Cathrine (Journal article; Peer reviewed, 2023)
      Background: Genetic testing has become an integrated part of health care for patients with breast or ovarian cancer, and the increasing demand for genetic testing is accompanied by an increasing need for easy access to ...

    • Evaluation of the sublingual route for administration of influenza vaccines in a murine model 

      Gjeraker, Ingrid Hjetland (Master thesis, 2011-05-19)
      Influenza is a one of the most important respiratory viruses, and it infects millions of people every year. Due to mutational changes in the virus genome (antigenic drift), influenza cause occasional pandemics. Pandemic ...

    • Evaluation of β-catenin inhibition of axitinib and nitazoxanide in human monocyte-derived dendritic cells 

      Azeem, Waqas; Bakke, Ragnhild Maukon; Gabriel, Benjamin; Appel, Silke; Øyan, Anne Margrete; Kalland, Karl-Henning (Journal article; Peer reviewed, 2021)
      Modulation of β-catenin signaling has attractive therapeutic potential in cancer immunotherapy. Several studies have found that β-catenin can mediate immune evasion in cancer and promote anti-inflammatory features of ...

    • Evaluering av antiemetikabehandling av kvinner hospitalisert med Hyperemesis Gravidarum 

      Kristiansen, Cathrine (Master thesis, 2016-05-20)
      Hyperemesis Gravidarum (HG), en alvorlig form for svangerskapskvalme, fører til vekttap, redusert livskvalitet, sykemeldinger og ofte sykehusinnleggelser. Antiemetika kan redusere kvalmen hos HG-pasienter, men i Norge er ...

    • Evaluering av et kortformat e-læringsprogram og dets effekt på apotekansattes kommunikasjon med ungdommer som vil kjøpe reseptfrie smertestillende legemidler i apotek 

      Nilsen, Guro Flatlandsmo (Master thesis, 2023-05-22)
      Bakgrunn: Omtrent 1 av 5 norske ungdommer i aldersgruppen 13–18 år, bruker smertestillende legemidler minst ukentlig (1). Samtidig har Giftinformasjonen de siste årene rapportert om en økning i antall henvendelser om ...