Blar i Faculty of Medicine på tittel
Viser treff 4680-4699 av 8812
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Involvement of the 14-3-3 Gene Family in Autism Spectrum Disorder and Schizophrenia: Genetics, Transcriptomics and Functional Analyses
(Journal article; Peer reviewed, 2020)The 14-3-3 protein family are molecular chaperones involved in several biological functions and neurological diseases. We previously pinpointed YWHAZ (encoding 14-3-3ζ) as a candidate gene for autism spectrum disorder (ASD) ... -
Involvement of the Private Retail Pharmacies in Pakistan Tuberculosis Control
(Master thesis, 2015-11-29)Tuberculosis is the second leading cause of death globally from a contagious disease. Pakistan is at 4th position among the twenty two high TB burden countries. National tuberculosis control programme (NTP) Pakistan has ... -
Involving people with diabetes and the wider community in diabetes research: a realist review protocol
(Peer reviewed; Journal article, 2015-11-04)Background: Patient and public involvement in diabetes research is now actively encouraged in different countries because it is believed that involving people with experience of the condition will improve the quality and ... -
Iodine concentration in breastmilk and urine among lactating women of Bhaktapur, Nepal
(Peer reviewed; Journal article, 2016-04-28)Adequate iodine concentration in breastmilk (BMIC) is essential for optimal neonatal thyroid hormone synthesis and neurological development in breastfed infants. For many decades, iodine deficiency has been a public health ... -
Iodine content of dietary supplements available on the Norwegian market
(Master thesis, 2021-05-18)Background: Insufficient iodine intake has been reported in groups of the Norwegian population. This is of concern, as iodine is an essential nutrient required throughout life. With few dietary sources of iodine, supplementation ... -
Iodine deficiency in a study population of Norwegian pregnant women - results from the Little in Norway study (LiN)
(Peer reviewed; Journal article, 2018-04-20)Iodine sufficiency is particularly important in pregnancy, where median urinary iodine concentration (UIC) in the range of 150–250 µg/L indicates adequate iodine status. The aims of this study were to determine UIC and ... -
Iodine Nutrition and Iodine Supplement Initiation in Association with Thyroid Function in Mildly-to-Moderately Iodine-Deficient Pregnant and Postpartum Women
(Journal article; Peer reviewed, 2021)Background: Whereas the adverse effects of severe iodine deficiency during pregnancy are well documented, the effects of mild-to-moderate deficiency are not well established. Objectives: We aimed to explore whether ... -
Iodine Nutrition and Thyroid Function in Habitual Seaweed Consumers at Baseline and after a 6-week Cessation of Seaweed Intake
(Master thesis, 2023-05-15)Bakgrunn/introduksjon: Tang og tare, eller makroalger, har blitt mer og mer populært i vesten de siste årene. Makroalger kan være kilder til jod, men inter- og intraartsvariabilitet i jodnivåer kan også føre til overflødige ... -
Iodine Nutrition in Children ≤2 years of Age in Norway
(Journal article; Peer reviewed, 2023)Background As a component of the thyroid hormones (THs), iodine is vital for normal neurodevelopment during early life. However, both deficient and excess iodine may affect TH production, and data on iodine status in ... -
Iodine status and thyroid function in a group of seaweed consumers in Norway
(Journal article; Peer reviewed, 2020)Seaweeds, or macroalgae, may be a good dietary iodine source but also a source of excessive iodine intake. The main aim in this study was to describe the iodine status and thyroid function in a group of macroalgae consumers. ... -
Iodine status in Norwegian preschool children and associations with dietary iodine sources: the FINS-KIDS study
(Peer reviewed; Journal article, 2018)Purpose. Iodine is an essential trace element necessary for thyroid hormone synthesis. Iodine deficiency is a continuing public health problem despite international efforts to eliminate it. Studies on iodine status in ... -
Iodine status in Norwegian preschool children and significance of dietary sources of iodine and parental socio-economic factors - A cross-sectional study
(Master thesis, 2016-05-15)Iodine is an essential trace element with important physiological effects in the human body. Iodine is necessary for thyroid hormone synthesis. The hormones are needed for tissue development in the central nervous system, ... -
Iodine status in women attending Mnazi Mmoja Hospital in Zanzibar: a matched case-control study
(Journal article; Peer reviewed, 2021)Background Iodine deficiency can have adverse health effects in all age groups affecting growth, development and cognitive functions as well as the incidence of goitre. Worldwide, the most important dietary source of ... -
Iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from Streptosporangium sp. induces apoptosis selectively in myeloid leukemia cell lines and patient cells
(Peer reviewed; Journal article, 2013-01-30)Despite recent improvement in therapy, acute myeloid leukemia (AML) is still associated with high lethality. In the presented study, we analyzed the bioactive compound iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from a ... -
Ionic strength and calcium regulate membrane interactions of myelin basic protein and the cytoplasmic domain of myelin protein zero
(Peer reviewed; Journal article, 2019)The formation of a mature myelin sheath in the vertebrate nervous system requires specific protein-membrane interactions. Several myelin-specific proteins are involved in stacking lipid membranes into multilayered structures ... -
IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy
(Peer reviewed; Journal article, 2015-04)Objectives: Biomarkers for diagnosis and therapy efficacy in tuberculosis (TB) are requested. We have studied biomarkers that may differentiate between active and latent TB infection (LTBI), the influence of HIV infection ... -
IP-10 dried blood spots assay monitoring treatment efficacy in extrapulmonary tuberculosis in a low-resource setting
(Peer reviewed; Journal article, 2019-03-07)Treatment efficacy is difficult to evaluate in extrapulmonary tuberculosis (EPTB) patients. Interferon-γ inducible protein (IP-)10 has been suggested as a biomarker for response to treatment. We have investigated if IP-10 ... -
Ipilimumab in a real-world population: A prospective Phase IV trial with long-term follow-up
(Journal article; Peer reviewed, 2022)Ipilimumab was the first treatment that improved survival in advanced melanoma. Efficacy and toxicity in a real-world setting may differ from clinical trials, due to more liberal eligibility criteria and less intensive ... -
IPLOS-registrering mellom statlige styringsidealer og lokale realiteter, hvordan varierer praksis i kartlegging av omsorgsbehov? Kvalitativ intervjuundersøkelse med IPLOS-kontakter i ni kommuner i Vest-Agder
(Master thesis, 2011-11-10)Background: IPLOS (individual-based care and care statistics) are part of health personnel documentation required for care and services to users who seek or receive local care services. National Target by introducing IPLOS ... -
IPSS “bother question” score predicts health-related quality of life better than total IPSS score
(Journal article; Peer reviewed, 2022)Objective The objective of this study was to investigate the role of bothersomeness of urinary symptoms on the general health-related quality of life (HRQoL) of patients with benign prostatic hyperplasia. We hypothesised ...