Blar i Department of Clinical Medicine på tittel
Viser treff 1824-1843 av 2085
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Simulation-based team-training in acute stroke: Is it safe to speed up?
(Journal article; Peer reviewed, 2022)Background In acute ischemic stroke (AIS), rapid treatment with intravenous thrombolysis (IVT) is crucial for good clinical outcome. Weekly simulation-based team-training of the stroke treatment team was implemented, ... -
Simultaneous bilateral aqueous misdirection following certolizumab therapy for rheumatoid arthritis
(Journal article; Peer reviewed, 2020)Aqueous misdirection syndrome is a rare, incompletely understood, sight-threatening eye condition that is difficult to diagnose and treat. We present a case of simultaneous bilateral aqueous misdirection following the ... -
Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps
(Journal article; Peer reviewed, 2021)The timing of surgical resection of synchronous liver metastases from colorectal cancer has been debated for decades. Several strategies have been proposed, but high-level evidence remains scarce. Simultaneous resection ... -
Single use flexible ureteroscopes: Current status and future directions
(Journal article; Peer reviewed, 2023)Introduction: Single use ureteroscopes are a technological innovation that have become available in the past decade and gained increased popularity. To this end, there are now an increasing number of both benchside and ... -
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
(Journal article; Peer reviewed, 2021)Prostate cancer is heterogeneous and patients would benefit from methods that stratify those who are likely to respond to systemic therapy. Here, we employ single-cell assays for transposase-accessible chromatin (ATAC) and ... -
Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, noninferiority, double-blinded, randomised and placebocontrolled trial
(Journal article; Peer reviewed, 2022)Background There is limited evidence regarding optimal duration of antibiotic treatment in neuroborreliosis. We aimed to compare efficacy and safety of oral doxycycline for 2 and 6 weeks in European Lyme neuroborreliosis ... -
Six versus two weeks treatment with doxycycline in Lyme neuroborreliosis: the protocol of a multicentre, non-inferiority, double-blinded and randomised controlled trial
(Peer reviewed; Journal article, 2019)Introduction: Current treatment guidelines for European Lyme neuroborreliosis (LNB) recommend cephalosporins, penicillin or doxycycline for 14–28 days but evidence for optimal treatment length is poor. Treatment lengths ... -
Sixteen-week multicentre randomised controlled trial to study the effect of the consumption of an oat beta-glucanenriched bread versus a whole-grain wheat bread on glycaemic control among persons with pre-diabetes: a study protocol of the CarbHealth study
(Journal article; Peer reviewed, 2022)Introduction In 2012, the estimated global prevalence of pre-diabetes was 280 million, and the prevalence is expected to rise to 400 million by 2030. Oat-based foods are a good source of beta-glucans, which have been ... -
Sjögren’s syndrome: studying the disease in mice
(Peer reviewed; Journal article, 2011-06-13)Sjögren’s syndrome (SS), a systemic autoimmune disease, is characterized by infl ammation of exocrine tissues accompanied by a signifi cant loss of their secretory function. Clinical symptoms develop late and there are no ... -
Sjøfolks syn- har vi riktig fokus på helsekrav og undersøkelsesmetode?
(Journal article, 2008)En vanlig synsundersøkelse måler skarpsyn, men sier ingenting om evnen til å se kontraster. Spesielt i mørke, tåke eller motlys er godt kontrastsyn vel så viktig, når man holder utkikk på broen. -
Sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study
(Peer reviewed; Journal article, 2013-02-14)Background: Our aim was to compare subjective and objective sleep quality and arousal in migraine and to evaluate the relationship between sleep quality and pain thresholds (PT) in controls, interictal, preictal and postictal ... -
Sleep-related and non-sleep-related migraine: interictal sleep quality, arousals and pain thresholds
(Peer reviewed; Journal article, 2013-08-06)Background: The mechanisms associating sleep and migraine are unknown. No previous polysomnographic (PSG) or pain-threshold (PT) study has compared patients with sleep-related migraine attacks (SM), non-sleep related ... -
Social media in surgery: evolving role in research communication and beyond
(Journal article; Peer reviewed, 2021)Purpose To present social media (SoMe) platforms for surgeons, how these are used, with what impact, and their roles for research communication. Methods A narrative review based on a literature search regarding social ... -
SonoVue® vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma?
(Journal article; Peer reviewed, 2022)The use of ultrasound and microbubbles to enhance therapeutic efficacy (sonoporation) has shown great promise in cancer therapy from in vitro to ongoing clinical studies. The fastest bench-to-bedside translation involves ... -
Sosiale skilnadar i kostvanar blant ungdom i Sogn og Fjordane i perioden 1997 - 2009
(Master thesis, 2014-05-15)Social disparities in health follow a gradient through the whole population, the social gradient in health. People with higher education, better occupational status and income live on average longer lives and have better ... -
Source control in emergency general surgery: WSES, GAIS, SIS-E, SIS-A guidelines
(Journal article; Peer reviewed, 2023)Intra-abdominal infections (IAI) are among the most common global healthcare challenges and they are usually precipitated by disruption to the gastrointestinal (GI) tract. Their successful management typically requires ... -
Spastic paraplegia type 7 is associated with multiple mitochondrial DNA deletions
(Peer reviewed; Journal article, 2014-01-22)Spastic paraplegia 7 is an autosomal recessive disorder caused by mutations in the gene encoding paraplegin, a protein located at the inner mitochondrial membrane and involved in the processing of other mitochondrial ... -
Spatial immunophenotyping of the tumour microenvironment in non–small cell lung cancer
(Journal article; Peer reviewed, 2023)Introduction: Immune cells in the tumour microenvironment are associated with prognosis and response to therapy. We aimed to comprehensively characterise the spatial immune phenotypes in the mutational and clinicopathological ... -
Specific neuropsychiatric symptoms are associated with functional decline trajectories in Alzheimer’s disease and Lewy body dementia: a five-year follow-up study
(Journal article; Peer reviewed, 2023-10-17)Background: Neuropsychiatric symptoms (NPS) are often overlooked and under-identified symptoms associated with dementia, despite their significant impact on the prognosis of individuals living with the disease. The specific ... -
Spike count and morphology in the classification of epileptiform discharges
(Journal article; Peer reviewed, 2023)Purpose: The purpose of this study is to investigate the impact of Bergen Epileptiform Morphology Score (BEMS) and interictal epileptiform discharge (IED) candidate count in EEG classification. Methods: We included 400 ...