Blar i Department of Clinical Medicine på tittel
Viser treff 1069-1088 av 1922
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K+ regulates relocation of Pellino-2 to the site of NLRP3 inflammasome activation in macrophages
(Journal article; Peer reviewed, 2021)Pellino proteins are E3 ubiquitin ligases involved in the innate immune system. Recently, Pellino-2 was reported to modulate the activation of the mouse Nlrp3 inflammasome. We examined the intracellular localization of ... -
Kartlegging av jernstatus og betydningen av kosthold og sosioøkonomisk status hos 14-15 -åringer i Bergen Kommune
(Master thesis, 2016-05-15)Iron deficiency is one of the most prominent nutritional deficiencies worldwide. Despite several attempts to reduce both iron deficiency and anemia, it has become a persistent problem, also in the industrialized parts of ... -
Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma
(Peer reviewed; Journal article, 2010-04-14)Background: Tumor cell proliferation is a predictor of survival in cutaneous melanoma. The aim of the present study was to evaluate the prognostic impact of mitotic count, Ki-67 expression and novel proliferation markers ... -
Kidney biopsy diagnosis in childhood in the Norwegian Kidney Biopsy Registry and the long-term risk of kidney replacement therapy: a 25-year follow-up
(Journal article; Peer reviewed, 2022)Background: There is scarce information on biopsy-verified kidney disease in childhood and its progression to chronic kidney disease stage 5 (CKD 5). This study aims to review biopsy findings in children, and to investigate ... -
The kinetics of gut microbial community composition in patients with irritable bowel syndrome following fecal microbiota transplantation
(Peer reviewed; Journal article, 2018-11-14)Background: Gut microbiota alterations are important in irritable bowel syndrome (IBS). The aim was to investigate the effect of fecal microbiota transplantation (FMT) on gut microbiota and the symptoms in patients with ... -
KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer
(Peer reviewed; Journal article, 2012)BACKGROUND: Three quarter of endometrial carcinomas are treated at early stage. Still, 15 to 20% of these patients experience recurrence, with little effect from systemic therapies. Homo sapiens v-Ki-ras2 Kirsten rat sarcoma ... -
KRAS mutation analysis by droplet digital PCR of duodenal juice from patients with MODY8 and other pancreatic diseases
(Journal article; Peer reviewed, 2021)Background Maturity-onset diabetes of the young type 8 (MODY8 or CEL-MODY) is an inherited pancreatic disease characterized by chronic inflammation of the pancreas and diabetes. It is not known whether MODY8 patients ... -
Labour onset and early labour. An exploration of first-time mothers’ and midwives’ experiences
(Doctoral thesis, 2011-10-28)This dissertation is about how women experience waiting for the onset of labour, and how first-time mothers and midwives communicate during the early phases of labour. Most women in Norway give birth in public hospitals, ... -
Lack of Association Between GBA Mutations and Motor Complications in European and American Parkinson’s Disease Cohorts
(Journal article; Peer reviewed, 2021)Background: Motor complications are a consequence of the chronic dopaminergic treatment of Parkinson’s disease (PD) and include levodopa-induced dyskinesia (LIDs) and motor fluctuations (MF). Currently, evidence is on ... -
Lactate is associated with mortality in very old intensive care patients suffering from COVID-19: results from an international observational study of 2860 patients
(Journal article; Peer reviewed, 2021)Purpose: Lactate is an established prognosticator in critical care. However, there still is insufficient evidence about its role in predicting outcome in COVID-19. This is of particular concern in older patients who have ... -
Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in utero – the Norwegian Mother and Child Cohort Study
(Peer reviewed; Journal article, 2020)Background and purpose: The purpose was to examine the consequences of antiepileptic drug (AED) exposure during pregnancy on language abilities in children aged 5 and 8 years of mothers with epilepsy. Methods: The study ... -
Large-scale resting state network correlates of cognitive impairment in Parkinson’s disease and related dopaminergic deficits
(Peer reviewed; Journal article, 2014-04-03)Cognitive impairment is a common non-motor feature of Parkinson’s disease (PD). Understanding the neural mechanisms of this deficit is crucial for the development of efficient methods for treatment monitoring and augmentation ... -
Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis
(Peer reviewed; Journal article, 2017)Background: Most patients with amyotrophic lateral sclerosis (ALS) are treated with mechanical insufflation–exsufflation (MI-E) in order to improve cough. This method often fails in ALS with bulbar involvement, allegedly ... -
Larynx during exercise: the unexplored bottleneck of the airways
(Peer reviewed; Journal article, 2014-07-18)Exercise-induced shortness of breath is not uncommon in otherwise healthy young people. Based on the presenting symptoms alone, it is challenging to distinguish exercise-induced asthma (EIA) from exercise-induced obstruction ... -
Larynx in exercising humans. The unexplored bottleneck of the airways
(Doctoral thesis, 2012-06-21) -
Late Onset Myasthenia Gravis Is Associated with HLA DRB1*15:01 in the Norwegian Population
(Peer reviewed; Journal article, 2012-05-09)Background: Acquired myasthenia gravis (MG) is a rare antibody-mediated autoimmune disease caused by impaired neuromuscular transmission, leading to abnormal muscle fatigability. The aetiology is complex, including genetic ... -
Late-Stage Prostate Cancer and Prostate Cancer Mortality : A Population-Based Study
(Doctoral thesis, 2019-11-29)AIMS OF THE THESIS The aim of this thesis was to provide a better understanding of the final stages of PCa, metastatic castration resistant PCa and PCa death. We further aimed to address the consequences of possible ... -
Left ventricular ejection fraction and adjudicated, cause-specific hospitalizations after myocardial infarction complicated by heart failure or left ventricular dysfunction
(Peer reviewed; Journal article, 2019)Background: Reduced left ventricular ejection fraction (LVEF) after acute myocardial infarction (MI) increases risk of cardiovascular (CV) hospitalizations, but evidence regarding its association with non-CV outcome is ... -
Left ventricular geometry and function in Tanzanian patients with hypertension and diabetes
(Doctoral thesis, 2013-02-15)From echocardiographic studies in hypertension, African Americans have been found to be more prone to develop cardiac target-organ damage than Caucasians. Hypertension is among the major upcoming health problems in Africa. ...