Blar i Department of Clinical Medicine på tittel
Viser treff 1570-1589 av 1650
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Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA
(Journal article; Peer reviewed, 2022)While DNA methylation is established as a major regulator of gene expression in the nucleus, the existence of mitochondrial DNA (mtDNA) methylation remains controversial. Here, we characterized the mtDNA methylation landscape ... -
Ultrasonographic evaluation of disease activity in Crohn’s Disease
(Doctoral thesis, 2020-09-21)Background: Crohn's disease (CD) is a chronic inflammatory disorder in the gastrointestinal (GI) tract, characterized by alternating periods of remission and relapse. Patients’ symptoms do not reliably represent inflammatory ... -
Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys
(Journal article; Peer reviewed, 2021-11-29)The use of ultrasound and microbubble-enhanced drug delivery, commonly referred to as sonoporation, has reached numerous clinical trials and has shown favourable results. Nevertheless, the microbubbles and acoustic path ... -
Ultrasound Detection of Pneumothorax. Development of a porcine pneumothorax model to assess and teach lung ultrasound diagnostics.
(Doctoral thesis; Peer reviewed, 2013-10-21)Background: Pneumothorax (PTX) is common after blunt chest injury, and failure to diagnose and rapidly treat an enlarging PTX may cause patient death. The anteroposterior supine chest x-ray (CXR) is the least sensitive of ... -
Ultrasound echo-intensity predicts severe Pancreatic affection in cystic fibrosis patients
(Peer reviewed; Journal article, 2015-03-24)Background: Pancreatic destruction affects the majority of patients with cystic fibrosis. We aimed to relate ultrasound findings to exocrine pancreatic function and cystic fibrosis genotype. Methods: Patients with cystic ... -
Ultrasound imaging for assessing functions of the GI tract
(Journal article; Peer reviewed, 2021)Objective: In the following review we outline how ultrasound can be used to measure physiological processes in the gastrointestinal tract. Approach: We have investigated the potential of ultrasound in assessing ... -
Ultrasound Strain Rate Imaging in Functional Dyspepsia : in-vitro and clinical evaluation
(Doctoral thesis, 2008-06-20)Functional dyspepsia (FD) is a chronic condition that is characterized by abdominal pain or discomfort, nausea, vomiting, early satiation and abdominal fullness. The Rome III classification of functional gastrointestinal ... -
Ultrasound-Assisted Endoscopic Removal of Pretibial Cysts Related to Biointerference Screw Degradation
(Journal article; Peer reviewed, 2021)We report on the treatment of cases of painful subcutaneous pretibial cyst due to broken and displaced materials of only partly absorbed bioabsorbable interference screws used for anterior cruciate ligament reconstruction. ... -
Umbilical vein constriction at the abdominal wall An ultrasound study in low risk pregnancies
(Doctoral thesis, 2005-05-18)The umbilical vein is the only vessel supplying the fetus with blood supplying oxygen and nutrients from the placenta. Case reports indicate that the fetal end of the umbilical cord is susceptible to mechanical complications. ... -
The unmet need for treatment of children with musculoskeletal impairment in Malawi
(Journal article; Peer reviewed, 2022)Background More than a billion people globally are living with disability and the prevalence is likely to increase rapidly in the coming years in low- and middle-income countries (LMICs). The vast majority of those living ... -
Unsubstantiated belief in the diagnostic accuracy of the triad of abusive head trauma may lead to incorrect diagnoses of alleged abuse cases
(Journal article; Peer reviewed, 2021) -
An Update on Vitamin D and Disease Activity in Multiple Sclerosis
(Peer reviewed; Journal article, 2019)Vitamin D and its main active metabolite 1,25-dihydroxyvitamin D serve a crucial role in maintenance of a healthy calcium metabolism, yet have additional roles in immune and central nervous system cell homeostasis. Serum ... -
Ureteral Strictures Following Ureteroscopic Stone Treatment
(Journal article; Peer reviewed, 2020)Background and Purpose: Ureteral stricture is a rare, but serious complication following ureteroscopy (URS) for stones. The aim of this study was to investigate how many patients ended up with a ureteral stricture after ... -
Ureteroscopy for stone disease in the paediatric population: lessons learned and outcomes in a Nordic setting
(Journal article; Peer reviewed, 2022)Introduction: Paediatric stone disease is rare in the Nordic communities. Still, the condition can require surgical intervention in the form of ureteroscopy (URS). Here, we report outcomes achieved at a regional (tertiary) ... -
Urinary iodine concentration and iodine intake in pregnant Norwegian women. Results from the “Little in Norway” Study (LiN)
(Master thesis, 2015-05-15)Background Iodine is an essential nutrient for the synthesis of thyroid hormones. Inadequate iodine intake is especially critical during pregnancy, lactation and early childhood. Iodine deficiency early in life impairs the ... -
Urinary proteomics in chronic kidney disease: diagnosis and risk of progression beyond albuminuria
(Peer reviewed; Journal article, 2015-08-07)Background: The contrast between a high prevalence of chronic kidney disease (CKD) and the low incidence of end-stage renal disease highlights the need for new biomarkers of progression beyond albuminuria testing. Urinary ... -
Urine and plasma concentrations of amino acids and plasma vitamin status differ, and are differently affected by salmon intake, in obese Zucker fa/fa rats with impaired kidney function and in Long-Evans rats with healthy kidneys
(Peer reviewed; Journal article, 2019)Kidney function affects amino acid metabolism and vitamin status. The aims of the present study were to investigate urine and plasma concentrations of amino acids as well as plasma vitamin status in rats with impaired renal ... -
Use of Benzodiazepines and Antipsychotic Drugs Are Inversely Associated with Acute Readmission Risk in Schizophrenia
(Journal article; Peer reviewed, 2022)Purpose: Little is known about the impact of different psychotropic drugs on acute readmission risk, when used concomitantly in a real-life setting. We aimed to investigate the association between acute readmission risk ... -
Use of immunohistochemical markers can refine prognosis in triple negative breast cancer
(Peer reviewed; Journal article, 2007-07-24)Background: Basal-like breast cancer has been extensively characterized on the basis of gene expression profiles, but it is becoming increasingly common for these tumors to be defined on the basis of immunohistochemical ... -
The use of prosthetic grafts in above-knee femoropopliteal bypass surgery : a clinical study of long-term results and risk factors for failure
(Doctoral thesis, 2007-05-24)Purpose: The purpose of this study has been to investigate the results of above-knee prosthetic femoropopliteal bypass surgery and to identify risk factors for complications and graft failure. The influence of comorbidity, ...