Blar i Department of Clinical Medicine på tittel
Viser treff 1204-1223 av 2171
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Labour onset and early labour. An exploration of first-time mothers’ and midwives’ experiences
(Doctoral thesis, 2011-10-28)This dissertation is about how women experience waiting for the onset of labour, and how first-time mothers and midwives communicate during the early phases of labour. Most women in Norway give birth in public hospitals, ... -
Lack of Association Between GBA Mutations and Motor Complications in European and American Parkinson’s Disease Cohorts
(Journal article; Peer reviewed, 2021)Background: Motor complications are a consequence of the chronic dopaminergic treatment of Parkinson’s disease (PD) and include levodopa-induced dyskinesia (LIDs) and motor fluctuations (MF). Currently, evidence is on ... -
Lactate is associated with mortality in very old intensive care patients suffering from COVID-19: results from an international observational study of 2860 patients
(Journal article; Peer reviewed, 2021)Purpose: Lactate is an established prognosticator in critical care. However, there still is insufficient evidence about its role in predicting outcome in COVID-19. This is of particular concern in older patients who have ... -
Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in utero – the Norwegian Mother and Child Cohort Study
(Peer reviewed; Journal article, 2020)Background and purpose: The purpose was to examine the consequences of antiepileptic drug (AED) exposure during pregnancy on language abilities in children aged 5 and 8 years of mothers with epilepsy. Methods: The study ... -
Laparoscopic rectal cancer resection yields comparable clinical and oncological results with shorter hospital stay compared to open access: a 5-year national cohort
(Journal article; Peer reviewed, 2023)Purpose Although widely applied, the results following laparoscopic rectal resection (LRR) compared to open rectal resection (ORR) are still debated. The aim of this study was to assess clinical short- and long-term ... -
Large-scale resting state network correlates of cognitive impairment in Parkinson’s disease and related dopaminergic deficits
(Peer reviewed; Journal article, 2014-04-03)Cognitive impairment is a common non-motor feature of Parkinson’s disease (PD). Understanding the neural mechanisms of this deficit is crucial for the development of efficient methods for treatment monitoring and augmentation ... -
Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis
(Peer reviewed; Journal article, 2017)Background: Most patients with amyotrophic lateral sclerosis (ALS) are treated with mechanical insufflation–exsufflation (MI-E) in order to improve cough. This method often fails in ALS with bulbar involvement, allegedly ... -
Larynx during exercise: the unexplored bottleneck of the airways
(Peer reviewed; Journal article, 2014-07-18)Exercise-induced shortness of breath is not uncommon in otherwise healthy young people. Based on the presenting symptoms alone, it is challenging to distinguish exercise-induced asthma (EIA) from exercise-induced obstruction ... -
Larynx in exercising humans. The unexplored bottleneck of the airways
(Doctoral thesis, 2012-06-21) -
Late Onset Myasthenia Gravis Is Associated with HLA DRB1*15:01 in the Norwegian Population
(Peer reviewed; Journal article, 2012-05-09)Background: Acquired myasthenia gravis (MG) is a rare antibody-mediated autoimmune disease caused by impaired neuromuscular transmission, leading to abnormal muscle fatigability. The aetiology is complex, including genetic ... -
Late-Stage Prostate Cancer and Prostate Cancer Mortality : A Population-Based Study
(Doctoral thesis, 2019-11-29)AIMS OF THE THESIS The aim of this thesis was to provide a better understanding of the final stages of PCa, metastatic castration resistant PCa and PCa death. We further aimed to address the consequences of possible ... -
Left ventricular ejection fraction and adjudicated, cause-specific hospitalizations after myocardial infarction complicated by heart failure or left ventricular dysfunction
(Peer reviewed; Journal article, 2019)Background: Reduced left ventricular ejection fraction (LVEF) after acute myocardial infarction (MI) increases risk of cardiovascular (CV) hospitalizations, but evidence regarding its association with non-CV outcome is ... -
Left ventricular geometry and function in Tanzanian patients with hypertension and diabetes
(Doctoral thesis, 2013-02-15)From echocardiographic studies in hypertension, African Americans have been found to be more prone to develop cardiac target-organ damage than Caucasians. Hypertension is among the major upcoming health problems in Africa. ... -
Left ventricular systolic deformation in subclinical metabolic cardiomyopathies
(Doctoral thesis, 2013-02-21)Cardiovascular disease is a significant contributor to morbidity and mortality in patients with inherited metabolic disorders or chronic kidney disease. Conventional echocardiography typically identifies cardiac involvement ... -
Leg cramps in pregnancy caused by chronic compartment syndrome and relieved by fasciotomy after childbirth
(Peer reviewed; Journal article, 2014-06)Key Clinical Message A case of intolerable leg pain in pregnancy, caused by Chronic Compartment Syndrome (CCS), is presented. Increasing amounts of opioids were given throughout the pregnancy. Anesthetical dilemmas and ... -
Legume consumption in adults and risk of cardiovascular disease and type 2 diabetes: a systematic review and meta-analysis
(Journal article; Peer reviewed, 2023)Objectives: This study aimed to systematically review the evidence for associations between consumption of legumes and cardiovascular disease (CVD), type 2 diabetes (T2D) and their risk factors among healthy adults. Methods: ... -
Length of hospital stay and risk of intensive care admission and in-hospital death among COVID-19 patients in Norway: a register-based cohort study comparing patients fully vaccinated with an mRNA vaccine to unvaccinated patients
(Journal article; Peer reviewed, 2022)Objectives We estimated the length of stay (LoS) in hospital and the intensive care unit (ICU) and risk of admission to ICU and in-hospital death among COVID-19 patients ≥18 years in Norway who had been fully vaccinated ... -
Leptin receptor signaling regulates protein synthesis pathways and neuronal differentiation in pluripotent stem cells
(Journal article; Peer reviewed, 2020)The role of leptin receptor (OB-R) signaling in linking pluripotency with growth and development and the consequences of dysfunctional leptin signaling on progression of metabolic disease is poorly understood. Using a ... -
Leukocyte transmigration into tissue-engineered constructs is influenced by endothelial cells through Toll-like receptor signaling
(Peer reviewed; Journal article, 2014-12-20)Introduction Inflammation plays a crucial role in tissue regeneration, wound healing, and the success of tissue-engineered constructs. The aim of this study was to investigate the influence of human umbilical vein endothelial ... -
The level of inflammatory tear cytokines is elevated in congenital Aniridia and associated with meibomian gland dysfunction
(Peer reviewed; Journal article, 2018-04)Purpose: To investigate the tear cytokine profile in congenital aniridia, and correlate cytokine levels with ophthalmologic findings. Methods: We examined 35 patients with aniridia and 21 healthy controls. Tear fluid was ...