Browsing Department of Clinical Medicine by Title

Now showing items 1077-1096 of 1497

    • A pan-European survey of research in end-of-life cancer care 

      Sigurdardottir, Katrin Ruth; Haugen, Dagny Faksvåg; Bausewein, Claudia; Higginson, Irene J.; Harding, Richard; Rosland, Jan Henrik; Kaasa, Stein (Peer reviewed; Journal article, 2010-11-30)
      Background To date, there is no coordinated strategy for end-of-life (EOL) cancer care research in Europe. The PRISMA (Reflecting the Positive Diversities of European Priorities for Research and Measurement in End-of-life ...

    • Pancreatic exocrine insufficiency in diabetes is associated with autonomic dysfunction 

      Sangnes, Dag André; Bergmann, Elisabeth Sandvik; Moss, Rose Marie; Engjom, Trond; Søfteland, Eirik Wigtil (Journal article; Peer reviewed, 2021)
      Objectives: Pancreatic exocrine insufficiency (PEI) is prevalent in diabetes. Pathophysiological theories imply autoimmune destruction, lack of trophic effects of insulin or impaired neuronal stimulation, but the relationship ...

    • Pandemic influenza vaccines - the challenges 

      Haaheim, Lars Reinhardt; Madhun, Abdullah Sami; Cox, Rebecca Jane (Peer reviewed; Journal article, 2009-12-03)
      Recent years’ enzootic spread of highly pathogenic H5N1 virus among poultry and the many lethal zoonoses in its wake has stimulated basic and applied pandemic vaccine research. The quest for an efficacious, affordable and ...

    • Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis 

      Schubert, Manja; Panja, Debabrata; Haugen, Mette; Bramham, Clive R.; Vedeler, Christian A. (Peer reviewed; Journal article, 2014-12)
      Paraneoplastic cerebellar degeneration (PCD) is characterized by loss of Purkinje cells (PCs) associated with progressive pancerebellar dysfunction in the presence of onconeural Yo antibodies. These antibodies recognize ...

    • Paraneoplastic cerebellar degeneration: Characterizing the Yo antibody antigens 

      Kråkenes, Torbjørn (Doctoral thesis, 2021-03-16)
      Background: The pathogenesis of paraneoplastic cerebellar degeneration (PCD) with Yo-antibodies is unclear. The disease is generally accepted as immune-mediated, but whether the Yo antibodies themselves are pathogenic ...

    • Paraneoplastic syndrome-associated neuronal antibodies in adult ADHD 

      Haukanes, Bjørn Ivar; Hegvik, Tor-Arne; Eichler, Tilo Wolf; Haavik, Jan; Vedeler, Christian A. (Peer reviewed; Journal article, 2015-09-01)
      A high seroprevalence of Yo antibodies targeting cerebellar Purkinje cells was recently reported in children with attention deficit/hyperactivity disorder (ADHD). We investigated the presence of 8 paraneoplastic neurological ...

    • Parenteral nutrition in patients with incurable cancer: A retrospective study of current practice at Haukeland University Hospital 

      Markhus, Emilie Hjønnevåg (Master thesis, 2020-06-17)
      Background: The use of PN therapy in patients living with incurable cancer is understudied, and there is a need for a stronger evidence base regarding this treatment in patients with incurable cancer. Aims: This study aimed ...

    • Parenteral Vaccination against Influenza Does Not Induce a Local Antigen-Specific Immune Response in the Nasal Mucosa 

      Brokstad, Karl Albert; Eriksson, Jens-Christian Haug; Cox, Rebecca Jane; Tynning, Turid Liv; Olofsson, Jan; Jonsson, Roland; Davidsson, Åke (Peer reviewed; Journal article, 2002-03-19)
      The immune response in the nasal mucosa to influenza vaccination in 23 patients scheduled for tonsillectomy was studied. A statistically significant increase in influenza virus–specific serum and oral fluid antibodies was ...

    • Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells 

      Valvatne, Monica Dalva; el Jellas, Khadija; Gravdal, Anny; Njølstad, Pål Rasmus; Molven, Anders; Fjeld, Karianne; Lugea, Aurelia; Pandol, Stephen J; Waldron, Richard T; Lavik, Ida; Johansson, Bente B. (Journal article; Peer reviewed, 2020)
      Mutations in the gene encoding the digestive enzyme carboxyl ester lipase (CEL) are linked to pancreatic disease. The CEL variant denoted CEL-HYB predisposes to chronic pancreatitis, whereas the CEL-MODY variant causes ...

    • Pathophysiology of idiopathic gastroparesis and implications for therapy 

      Bekkelund, Mattis; Sangnes, Dag André; Hatlebakk, Jan Gunnar; Aabakken, Lars (Peer reviewed; Journal article, 2019)
      Objectives: Idiopathic gastroparesis is a gastric motility disorder characterized by chronic upper gastrointestinal symptoms and delayed gastric emptying without an identifiable underlying condition. This review summarizes ...

    • Patient and surgical factors affecting procedure duration and revision risk due to deep infection in primary total knee arthroplasty 

      Badawy, Mona; Espehaug, Birgitte; Fenstad, Anne Marie; Indrekvam, Kari; Dale, Håvard; Havelin, Leif Ivar; Furnes, Ove (Peer reviewed; Journal article, 2017-12-21)
      Background: The aim of this study was to assess which patient and procedure factors affected both the risk of infection as well as procedure duration. Additionally, to assess if procedure duration affected the revision ...

    • The patient perspective: Quality of life in advanced heart failure with frequent hospitalisations 

      Nieminen, Markku S.; Dickstein, Kenneth; Fonseca, Cândida; Serrano, Jose Magaña; Parissis, John; Fedele, Francesco; Wikström, Gerhard; Agostoni, Piergiuseppe; Atar, Shaul; Baholli, Loant; Brito, Dulce; Colet, Josep Comin; Édes, István Ferenc; Gómez Mesa, Juan E.; Gorjup, Vojka; Garza, Eduardo Herrera; González Juanatey, José R.; Karanovic, Nenad; Karavidas, Apostolos; Katsytadze, Igor; Kivikko, Matti; Matskeplishvili, Simon; Merkely, Béla; Morandi, Fabrizio; Novoa, Angel; Oliva, Fabrizio; Ostadal, Petr; Pereira-Barretto, Antonio; Pollesello, Piero; Rudiger, Alain; Schwinger, Robert HG; Wieser, Manfred; Yavelov, Igor; Zymlinski, Robert (Peer reviewed; Journal article, 2015-07-15)
      End of life is an unfortunate but inevitable phase of the heart failure patients' journey. It is often preceded by a stage in the progression of heart failure defined as advanced heart failure, and characterised by poor ...

    • Patient safety in pre-hospital emergency tracheal intubation: a comprehensive meta-analysis of the intubation success rates of EMS providers 

      Lossius, Hans Morten; Røislien, Jo; Lockey, David J. (Peer reviewed; Journal article, 2012-02-11)
      Introduction: Pre-hospital airway management is a controversial subject, but there is general agreement that a small number of seriously ill or injured patients require urgent emergency tracheal intubation (ETI) and ...

    • A Patient With Maculopapular Rash and Lichenoid Skin Damage Caused by Ponatinib 

      Teigen, Ingrid Anna; Sæle, Anna Kristine Myrmel; Reikvam, Håkon (Journal article; Peer reviewed, 2020)
      Tyrosine kinase inhibitors (TKIs) are invaluable for the treatment of patients with chronic myelogenous leukemia. Although TKIs are generally better tolerated than traditional chemotherapy, dermatologic side effects are ...

    • Patient-reported outcome after treatment for definite Lyme neuroborreliosis 

      Eikeland, Randi; Ljøstad, Unn; Helgeland, Geir; Sand, Geir; Flemmen, Heidi Øyen; Bø, Margrete Halvorsen; Nordaa, Ludmila; Owe, Jone Furulund; Mygland, Åse; Lorentzen, Åslaug Rudjord (Journal article; Peer reviewed, 2020)
      Objective To chart patient‐reported outcome measures (PROMs) in Norwegian patients treated for definite neuroborreliosis (NB). Material and Methods Adult patients treated for definite NB 1–10 years earlier supplied ...

    • Patient-Reported Outcome Measures after Endoscopic Retrograde Cholangiopancreatography: A Prospective, Multicenter Study 

      Glomsaker, Tom Birger; Hoff, Geir; Kvaløy, Jan Terje; Søreide, Kjetil; Aabakken, Lars; Søreide, Jon Arne; The Norwegian Gastronet ERCP group (Journal article, 2013)
      Objective: While patient-reported outcome measures (PROMs) in ERCP are scarce, these reports are important for making improvements in quality of care. This study sought to document patient satisfaction and specifically ...

    • Patient-reported outcome measures after hip fracture in patients with chronic cognitive impairment: results from 34.675 patients in the Norwegian Hip Fracture Register 

      Kristoffersen, Målfrid Holen; Dybvik, Eva Hansen; Steihaug, Ole Martin; Kristensen, Torbjørn; Engesæter, Lars B.; Ranhoff, Anette Hylen; Gjertsen, Jan-Erik (Journal article; Peer reviewed, 2021)
      Aims: Hip fracture patients have high morbidity and mortality. Patient-reported outcome measures (PROMs) assess the quality of care of patients with hip fracture, including those with chronic cognitive impairment (CCI). ...

    • Patient-reported outcomes in palliative gastrointestinal stenting: a Norwegian multicenter study 

      Larssen, Lene; Medhus, Asle W.; Hjermstad, Marianne J.; Kørner, Hartwig; Glomsaker, Tom Birger; Søberg, Taran; Gleditsch, Dagfinn; Hovde, Øistein; Nesbakken, Arild; Tholfsen, Jan K.; Skreden, Knut; Hauge, Truls (Peer reviewed; Journal article, 2011-04-13)
      Background The clinical effect of stent treatment has been evaluated by mainly physicians; only a limited number of prospective studies have used patient-reported outcomes for this purpose. The aim of this work was to study ...

    • Patients Referred to a Norwegian Trauma Centre: effect of transfer distance on injury patterns, use of resources and outcomes 

      Kristiansen, Thomas; Lossius, Hans Morten; Søreide, Kjetil; Steen, Petter Andreas; Gaarder, Christine; Næss, Pål A. (Peer reviewed; Journal article, 2011-06-16)
      Background: Triage and interhospital transfer are central to trauma systems. Few studies have addressed transferred trauma patients. This study investigated transfers of variable distances to OUH (Oslo University Hospital, ...

    • Patients with advanced cancer and depression report a significantly higher symptom burden than non-depressed patients 

      Grotmol, Kjersti Støen; Lie, Hanne Cathrine; Loge, Jon Håvard; Aass, Nina Kathrine; Haugen, Dagny Faksvåg; Stone, Patrick C; Kaasa, Stein; Hjermstad, Marianne Jensen (Peer reviewed; Journal article, 2019-04)
      Objective. Clinical observations indicate that patients with advanced cancer and depression report higher symptom burden than nondepressed patients. This is rarely examined empirically. Study aim was to investigate the ...