Blar i Department of Clinical Medicine på tittel
Viser treff 1071-1090 av 2065
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Integrated Genomic Analysis of the 8q24 Amplification in Endometrial Cancers Identifies ATAD2 as Essential to MYC-Dependent Cancers
(Peer reviewed; Journal article, 2013-02-05)Chromosome 8q24 is the most commonly amplified region across multiple cancer types, and the typical length of the amplification suggests that it may target additional genes to MYC. To explore the roles of the genes most ... -
Integrin a11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression
(Peer reviewed; Journal article, 2017-04)BACKGROUND: Cancer-associated fibroblasts (CAFs) were shown to be important for tumour progression in head and neck squamous cell carcinomas (HNSCCs). Their heterogeneity and lack of specific markers is increasingly ... -
Integrin α11β1 is expressed in breast cancer stroma and associates with aggressive tumor phenotypes
(Peer reviewed; Journal article, 2020)Cancer‐associated fibroblasts are essential modifiers of the tumor microenvironment. The collagen‐binding integrin α11β1 has been proposed to be upregulated in a pro‐tumorigenic subtype of cancer‐associated fibroblasts. ... -
Intense pulsed light treatment in meibomian gland dysfunction: Past, present, and future
(Journal article; Peer reviewed, 2023)Dry eye disease is a highly prevalent condition, which can substantially impair quality of life, work productivity, and vision. It is considered an inflammatory disease and the most common cause is meibomian gland dysfunction. ... -
Inter-hospital transfer: the crux of the trauma system, a curse for trauma registries
(Journal article, 2010-03-16)The inter-hospital transfer of patients is crucial to a well functioning trauma system, and the transfer process may serve as a quality indicator for regional trauma care. However, the assessment of the transfer process ... -
Interaction between ingested nutrients and gut endocrine cells in patients with irritable bowel syndrome (Review)
(Peer reviewed; Journal article, 2014-08)Several endocrine cell abnormalities have been reported in different segments of the gastrointestinal tract of patients with irritable bowel syndrome (IBS). These cells have specialized microvilli that project into the ... -
Interactions between Fusobacterium nucleatum and Primary Human Oral Cells: In Vitro Studies in Monolayer and Organotypic Culture Models
(Doctoral thesis, 2012-06-21)F. nucleatum is a Gram-negative bacterium, member of normal flora in the oral cavity, which has a major role in the formation of the subgingival biofilm. The adhesins expressed on the cell wall outer membrane confer F. ... -
Interdisciplinary Approaches Suggested for Children With Multiple Hospital Referrals Presenting With Non-specific Conditions
(Journal article; Peer reviewed, 2021)Aims: To describe the care patterns of patients with repeated referrals to both mental and somatic specialist healthcare, and to study their diagnostic processes. Methods: In a previous register study patients aged 6–12 ... -
An interdisciplinary intervention for children with complex health complaints; a feasibility study of selection criteria
(Journal article; Peer reviewed, 2023)Background: There is a need for re-designing the health service for children suffering from complex and compound health complaints. Based on a previous register study, we have developed criteria to select patients with ... -
Interictal epileptiform discharges vary across age groups
(Journal article; Peer reviewed, 2020-01)Objective: To investigate whether the occurrence and morphology of interictal epileptiform discharges (IEDs) in scalp-EEG change by age. Methods: 10,547 patients who had a standard or sleep deprived EEG recording reported ... -
Internalizing Symptom Profiles Among Youth in Foster Care: A Comparison Study
(Journal article; Peer reviewed, 2021)Background: A high prevalence of anxiety and depression is found among youth in foster care. There is limited knowledge on the anxiety and depression symptom profiles of youth in foster care. We examined latent profiles ... -
International variation in distribution of ASA class in patients undergoing total hip arthroplasty and its influence on mortality: data from an international consortium of arthroplasty registries
(Journal article; Peer reviewed, 2021)Background and purpose — A challenge comparing outcomes from total hip arthroplasty between countries is variation in preoperative characteristics, particularly comorbidity. Therefore, we investigated between-country ... -
Interobserver agreement and prognostic impact for MRI–based 2018 FIGO staging parameters in uterine cervical cancer
(Journal article; Peer reviewed, 2022)Objectives To evaluate the interobserver agreement for MRI–based 2018 International Federation of Gynecology and Obstetrics (FIGO) staging parameters in patients with cervical cancer and assess the prognostic value of ... -
Interstitial Fluid Colloid Osmotic Pressure in Healthy Children
(Peer reviewed; Journal article, 2015-04-08)Objective: The colloid osmotic pressure (COP) of plasma and interstitial fluid play important roles in transvascular fluid exchange. COP values for monitoring fluid balance in healthy and sick children have not been ... -
Interventions on arterial pressure and perfusion flow rate during cardiopulmonary bypass : effects on global fluid shifts, cerebral metabolic and structural markers in a porcine model
(Doctoral thesis, 2008-01-18)Global and regional organ perfusion during cardiopulmonary bypass (CPB) depends on hemodynamic parameters as mean arterial pressure (MAP) and perfusion flow rate. These parameters may also exert influence on the load of ... -
Intestinal barrier integrity in anorexia nervosa (a pilot study)
(Journal article; Peer reviewed, 2022)Objective There is no conclusive evidence for involvement of intestinal barrier alteration in the etiology of anorexia nervosa (AN). The aims of this pilot study were to identify serum markers of intestinal barrier integrity ... -
Intestinal permeability and gene expression after polyethylene and polyamide microplastic ingestion in Wistar rats
(Journal article; Peer reviewed, 2022)Microplastic particles are ubiquitous in the environment. However, little is known about their uptake and effects in humans or mammalian model organisms. Here, we studied the effects of pristine polyamide (15–20 µm) and ... -
Intestinal ultrasound early on in treatment follow-up predicts endoscopic response to anti-TNFα treatment in Crohn's disease
(Journal article; Peer reviewed, 2022)Background To assess treatment response, objective measures are superior to clinical improvement in Crohn’s disease [CD]. Intestinal ultrasound [IUS] is an attractive, non-invasive alternative to endoscopy, demonstrating ... -
Intestinal Ultrasound to Assess Disease Activity in Ulcerative Colitis: Development of a novel UC-Ultrasound Index
(Journal article; Peer reviewed, 2021)Introduction: Intestinal ultrasound [IUS] is useful to assess inflammation in ulcerative colitis [UC] patients. We aimed to develop an ultrasonographic activity index using endoscopy as the reference standard. Methods: ... -
Intracerebral Hemorrhage In Southern Norway. A study of incidence and outcome
(Doctoral thesis, 2013-11-29)Aims: We aimed to assess the incidence and baseline characteristics of first ever intracerebral hemorrhage (ICH) in Southern Norway leading to hospitalization, mortality rates after ICH and factors associated with 30-day ...