Browsing Department of Clinical Medicine by Title
Now showing items 1136-1155 of 2260
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Increased Sphingomyelin and Free Sialic Acid in Cerebrospinal Fluid of Kearns-Sayre Syndrome: New Findings Using Untargeted Metabolomics
(Journal article; Peer reviewed, 2023)Background: Kearns-Sayre syndrome (KSS) is caused by duplications and/or deletions of mitochondrial DNA (mtDNA) and is typically diagnosed based on a classic triad of symptoms with chronic progressive external ophthalmoplegia ... -
Increasing age of multiple sclerosis onset from 1920 to 2022: a population-based study
(Journal article; Peer reviewed, 2023)Objective To study the age at onset of relapsing–remitting multiple sclerosis (RRMS) during the past century. Methods This is a population-based cohort study of persons diagnosed with RRMS in Hordaland, Møre, and ... -
Increasing but levelling out risk of revision due to infection after total hip arthroplasty: a study on 108,854 primary THAs in the Norwegian Arthroplasty Register from 2005 to 2019
(Journal article; Peer reviewed, 2020)Background and purpose — Focus on prevention, surveillance, and treatment of infection after total hip arthroplasty (THA) in the last decade has resulted in new knowledge and guidelines. Previous publications have suggested ... -
Increasing risk of prosthetic joint infection after total hip arthroplasty. 2,778 revisions due to infection after 432,168 primary THAs in the Nordic Arthroplasty Register Association (NARA)
(Peer reviewed; Journal article, 2012-10)Background and purpose: The risk of revision due to infection after primary total hip arthroplasty (THA) has been reported to be increasing in Norway. We investigated whether this increase is a common feature in the Nordic ... -
Increasing risk of revision due to deep infection after hip arthroplasty. A study on 97,344 primary total hip replacements in the Norwegian Arthroplasty Register from 1987 to 2007
(Peer reviewed; Journal article, 2009-12)Background and purpose: Over the decades, improvements in surgery and perioperative routines have reduced the incidence of deep infections after total hip arthroplasty (THA). There is, however, some evidence to suggest ... -
Increasing risk of revision due to infection after primary total hip arthroplasty: results from the Nordic Arthroplasty Register Association
(Journal article; Peer reviewed, 2023)Background and purpose: The incidence of periprosthetic joint infection after total hip arthroplasty (THA) may be increasing. We performed time-trend analyses of risk, rates, and timing of revision due to infection after ... -
Increasing the Dose and/or Repeating Faecal Microbiota Transplantation (FMT) Increases the Response in Patients with Irritable Bowel Syndrome (IBS)
(Peer reviewed; Journal article, 2019-06-24)Background: Faecal microbiome transplantation (FMT) appears to be an effective method for treating irritable bowel syndrome (IBS) patients. However, it is not clear if a high transplant dose and/or repeating FMT are/is ... -
Increasing the transplant dose and repeating faecal microbiota transplantation results in the responses of male patients with IBS reaching those of females
(Journal article; Peer reviewed, 2023)Background Faecal microbiota transplantation (FMT) performed with a proper protocol is a safe treatment for IBS that has high efficacy and durable effects. Females have been reported to respond better than males to FMT. ... -
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
(Peer reviewed; Journal article, 2019)How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels ... -
Individual Variability in Reaction Time and Prediction of Clinical Response to Methylphenidate in Adult ADHD: A Prospective Open Label Study Using Conners’ Continuous Performance Test II
(Peer reviewed; Journal article, 2019)Objective: The aim of this study was to examine whether reaction time parameters in adult patients with ADHD could predict their response to methylphenidate (MPH). Method: Previously unmedicated patients (N = 123) were ... -
Infant growth in the KwaZulu-Natal province, South Africa: Results from the KwaZulu-Natal initiative for breastfeeding support (KIBS) survey II at 13-15 weeks and 6 months of age
(Master thesis, 2018-06-22)Background: Today, 155 million children under the age of five years are stunted in the world, 52 million are wasted, while 41 million are overweight. When these conditions exist at the same time, within an individual, ... -
Infantile external hydrocephalus : Epidemiological, radiological, clinical, cognitive, and social aspects
(Doctoral thesis, 2022-11-25)Bakgrunn: Ekstern hydrocefalus («utvendig vannhode») er en tilstand som kan sees hos noen spedbarn med raskt økende hodeomkrets. Radiologisk utredning viser utvidete, væskefylte hulrom på hjernens overflate, spesielt ... -
Infected total hip arthroplasty - Bacteriology and the role of operating room ventilation in the reduction of postoperative infection
(Doctoral thesis, 2020-10-09)Each year approximately 7,000 patients receive a total hip arthroplasty (THA) in Norway. The most common indication is osteoarthritis and most patients experience substantial pain relief postoperatively. A rare but much ... -
Infection after primary hip arthroplasty. A comparison of 3 Norwegian health registers
(Peer reviewed; Journal article, 2011-12)Background and purpose: The aim of the present study was to assess incidence of and risk factors for infection after hip arthroplasty in data from 3 national health registries. We investigated differences in risk patterns ... -
Infection after primary hip arthroplasty. Epidemiology, time trends and risk factors in data from national health registers. The Norwegian Arthroplasty Register
(Doctoral thesis, 2013-02-08)Every year, more than 10,000 Norwegians undergo hip replacement (7,360 THAs and 3,214 HAs in 2011). This may be due to osteoarthritis (OA), inflammatory joint disease, fractures, fracture sequelae, aseptic femoral head ... -
Inflammation markers in multiple sclerosis: CXCL16 reflects and may also predict disease activity
(Peer reviewed; Journal article, 2013-09-19)Background. Serum markers of inflammation are candidate biomarkers in multiple sclerosis (MS). ω-3 fatty acids are suggested to have anti-inflammatory properties that might be beneficial in MS. We aimed to explore the ... -
Inflammatory biomarkers in newly diagnosed patients with Parkinson’s disease and related neurodegenerative disorders
(Journal article; Peer reviewed, 2023)Background and Objectives Neuroinflammation contributes to Parkinson disease (PD) pathology, and inflammatory biomarkers may aid in PD diagnosis. Proximity extension assay (PEA) technology is a promising method for multiplex ... -
Inflammatory Stratification in Primary Sjögren’s Syndrome Reveals Novel Immune Cell Alterations in Patients’ Minor Salivary Glands
(Journal article; Peer reviewed, 2021)There is a critical need to deconvolute the heterogeneity displayed by the minor salivary glands of primary Sjögren’s syndrome (pSS) patients. This is challenging primarily because the disease etiology remains unknown. The ... -
Inflammatory tissue reactions around aseptically loose cemented hip prostheses: A retrieval study of the Spectron EF stem with Reflection All-Poly acetabular cup
(Journal article; Peer reviewed, 2022)The cemented Spectron EF stem in combination with the cemented non-crosslinked Reflection All-Poly cup showed a high rate of mid-term aseptic loosening. However, the failure mechanisms are not fully known. We assessed the ... -
Influence of circulatory shock at hospital admission on outcome after out-of-hospital cardiac arrest
(Journal article; Peer reviewed, 2022)Hypotension after cardiac arrest could aggravate prolonged hypoxic ischemic encephalopathy. The association of circulatory shock at hospital admission with outcome after cardiac arrest has not been well studied. The objective ...