Browsing Department of Clinical Medicine by Title
Now showing items 134-153 of 2120
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The association of partial pressures of oxygen and carbon dioxide with neurological outcome after out-of-hospital cardiac arrest: an explorative International Cardiac Arrest Registry 2.0 study
(Journal article; Peer reviewed, 2020)Background Exposure to extreme arterial partial pressures of oxygen (PaO2) and carbon dioxide (PaCO2) following the return of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest (OHCA) is common and may ... -
Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability
(Journal article; Peer reviewed, 2022)Importance: Women with epilepsy frequently need antiseizure medication (ASM) to prevent seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to AMSs is uncertain. Objective: To determine ... -
The association of prior paracetamol intake with outcome of very old intensive care patients with COVID-19: results from an international prospective multicentre trial
(Journal article; Peer reviewed, 2022)Background In the early COVID-19 pandemic concerns about the correct choice of analgesics in patients with COVID-19 were raised. Little data was available on potential usefulness or harmfulness of prescription free ... -
The Association of Sarcopenia and Central Obesity with Mortality Risk in Patients with Chronic Kidney Disease – a 2-Year Observational Study
(Journal article; Peer reviewed, 2023)Background Patients with chronic kidney disease (CKD) face numerous challenges regarding their nutritional status, including undernutrition, wasting, overweight, and obesity. However, there is a gap in the knowledge on ... -
Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients
(Journal article; Peer reviewed, 2021)Objectives: To evaluate the impact of SNCA polymorphisms originally identified as risk factors for Parkinson's disease (PD) on the clinical presentation and progression of the disease in a large cohort of population-based ... -
The association of the Activities of Daily Living and the outcome of old intensive care patients suffering from COVID-19
(Journal article; Peer reviewed, 2022)Purpose Critically ill old intensive care unit (ICU) patients suffering from Sars-CoV-2 disease (COVID-19) are at increased risk for adverse outcomes. This post hoc analysis investigates the association of the Activities ... -
Associations between ABO blood groups and pancreatic ductal adenocarcinoma: influence on resection status and survival
(Peer reviewed; Journal article, 2017-07)Both serology‐based and genetic studies have reported an association between pancreatic cancer risk and ABO blood groups. We have investigated this relationship in a cohort of pancreatic cancer patients from Western Norway ... -
Associations between nasal characteristics and sleep polygraphic data in patients suspected Obstructive Sleep Apnea
(Journal article; Peer reviewed, 2020)Background: The aim of the present study was to explore the relationships between Obstructive Sleep Apnea (OSA), daytime sleepiness, nasal geometry, nasal airflow, and patient- reported sino-nasal symptoms. Methodology: ... -
Associations between post-stroke motor and cognitive function: a cross-sectional study
(Journal article; Peer reviewed, 2021)Background Motor and cognitive impairments are frequently observed following stroke, but are often managed as distinct entities, and there is little evidence regarding how they are related. The aim of this study was to ... -
Associations between pressure pain threshold in the neck and postural control in patients with dizziness or neck pain - a cross-sectional study
(Peer reviewed; Journal article, 2019-11-10)Background: It is theorized that neck pain may cause reduced postural control due to the known physiological connection between the receptors in the cervical spine and the vestibular system. The purpose of this study was ... -
Associations between Serial Intravitreal Injections and Dry Eye
(Journal article; Peer reviewed, 2023)Purpose To investigate the effects of serial intravitreal injections (IVIs) on the ocular surface and meibomian glands (MGs) in patients treated with anti-vascular endothelial growth factor (anti-VEGF) for neovascular ... -
Attention deficit/hyperactivity disorder and occurrence of epilepsy, interictal epileptiform discharges and two years follow-up in children
(Doctoral thesis, 2016-06-15)The detection and treatment of both attention deficit/hyperactivity disorder (ADHD) and epilepsy in young patients are challenging. In some cases, the occurrence of interictal epileptiform discharges (IEDs) flowers the ... -
Attention-Deficit/Hyperactivity Disorder Symptom Dimensions Differentially Predict Adolescent Peer Problems: Findings From Two Longitudinal Studies
(Journal article; Peer reviewed, 2021)Introduction: Previous findings that inattention (IA) and hyperactive/impulsive (HI) symptoms predict later peer problems have been mixed. Utilizing two culturally diverse samples with shared methodologies, we assessed the ... -
Augmented reality versus standard tests to assess cognition and function in early Alzheimer’s disease
(Journal article; Peer reviewed, 2023)Augmented reality (AR) apps, in which the virtual and real world are combined, can recreate instrumental activities of daily living (IADL) and are therefore promising to measure cognition needed for IADL in early Alzheimer’s ... -
Automated segmentation of endometrial cancer on MR images using deep learning
(Journal article; Peer reviewed, 2021)Preoperative MR imaging in endometrial cancer patients provides valuable information on local tumor extent, which routinely guides choice of surgical procedure and adjuvant therapy. Furthermore, whole-volume tumor analyses ... -
Automated spectrophotometric bicarbonate analysis in duodenal juice compared to the back titration method
(Peer reviewed; Journal article, 2016-02-03)Objectives We have recently evaluated a short endoscopic secretin test for exocrine pancreatic function. Bicarbonate concentration in duodenal juice is an important parameter in this test. Measurement of bicarbonate by ... -
The autonomy of different aspects of Sjögren´s syndrome and their treatment in an experimental model: the use of comprehensive biomarker analyses to characterize the disease and the effect of heat-shock proteins in treatment intervention
(Doctoral thesis, 2008-06-20)Sjögren’s syndrome (SS) is a systemic rheumatic disease, in which the salivary and lacrimal glands are the principal targets of a pathological autoimmune reaction. Clinically, SS is manifested by keratoconjunctivitis sicca ... -
AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model
(Journal article; Peer reviewed, 2021)AXL tyrosine kinase activation enhances cancer cell survival, migration, invasiveness, and promotes drug resistance. AXL overexpression is typically detected in a high percentage of renal cell carcinomas (RCCs) and is ... -
AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction
(Peer reviewed; Journal article, 2019)The AXL receptor tyrosine kinase (RTK) is involved in partial epithelial-tomesenchymal transition (EMT) and inflammation – both main promoters of renal fibrosis development. The study aim was to investigate the role of AXL ... -
Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model
(Journal article; Peer reviewed, 2021)Renal fibrosis is a progressive histological manifestation leading to chronic kidney disease (CKD) and associated with mitochondrial dysfunction. In previous work, we showed that Bemcentinib, an Axl receptor tyrosine kinase ...