Browsing Department of Clinical Medicine by Title

Now showing items 1506-1525 of 2077

    • Patients’ and healthcare workers’ recommendations for a surgical patient safety checklist – a qualitative study 

      Harris, Kristin; Softeland, Eirik; Moi, Asgjerd Litleré; Harthug, Stig; Storesund, Anette; Jesuthasan, Sebastius; Sevdalis, Nick; Haugen, Arvid Steinar (Journal article; Peer reviewed, 2020)
      Background: Patients’ involvement in patient safety has increased in healthcare. Use of checklists may improve patient outcome in surgery, though few have attempted to engage patients’ use of surgical checklist. To identify ...

    • Patterns of local recurrence and dose fractionation of adjuvant radiation therapy in 462 patients with soft tissue sarcoma of extremity and trunk wall 

      Jebsen, Nina; Engellau, Jacob; Engström, Katarina; Bauer, Henrik C.; Monge, Odd R; Muren, Ludvig Paul; Eide, Geir Egil; Trovik, Clement; Bruland, Øyvind (Peer reviewed; Journal article, 2013-08-01)
      Purpose To study the impact of dose fractionation of adjuvant radiation therapy (RT) on local recurrence (LR) and the relation of LR to radiation fields. Methods and Materials LR rates were analyzed in 462 adult patients ...

    • Patterns of motor activity in spontaneously hypertensive rats compared to Wistar Kyoto rats 

      Fasmer, Ole Bernt; Johansen, Espen Borgå (Peer reviewed; Journal article, 2016-12-01)
      Background: Increased motor activity is a defining characteristic of patients with ADHD, and spontaneously hypertensive rats have been suggested to be an animal model of this disorder. In the present study, we wanted to ...

    • Patterns of transmitted HIV drug resistance in Europe vary by risk group 

      Frentz, Dineke; van de Vijver, David A.; Abecasis, Ana B.; Albert, Jan; Hamouda, Osamah; Jørgensen, Louise B.; Kücherer, Claudia; Struck, Daniel; Schmit, Jean-Claude; Vercauteren, Jürgen; Åsjø, Birgitta; Balotta, Claudia; Bergin, Colm; Beshkov, Danail; Camacho, Ricardo; Clotet, Bonaventura; Griskevicius, Algirdas; Grossman, Zehava; Horban, Andrzej; Kolupajeva, Tatjana; Korn, Klaus; Kostrikis, Leondios; Linka, Kirsi Litsola Marek; Nielsen, Claus; Otelea, Dan; Paraskevis, Dimitrios; Paredes, Roger; Poljak, Mario; Puchhammer-Stöckl, Elisabeth; Sönnerborg, Anders; Stanekova, Danica; Stanojevic, Maja; Vandamme, Anne-Mieke; Boucher, Charles A.B.; Wensing, Annemarie (Peer reviewed; Journal article, 2014-04-10)
      Background: In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to the ...

    • Pediatric prolonged-release melatonin for insomnia in children and adolescents with autism spectrum disorders 

      Schroder, Carmen M.; Banaschewski, Tobias; Fuentes, Joaquin; Hill, Catherine Mary; Hvolby, Allan; Posserud, Maj-Britt Rocio; Bruni, Oliviero (Journal article; Peer reviewed, 2021)
      Introduction: Insomnia is common among children and adolescents with Autism spectrum disorder (ASD). The first drug licensed for insomnia in this population, a pediatric-appropriate prolonged-release melatonin (PedPRM) ...

    • Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization 

      Cristea, Ileana; Bruland, Ove; Rødahl, Eyvind; Bredrup, Cecilie (Journal article; Peer reviewed, 2021)
      Pellino-2 is an E3 ubiquitin ligase that mediates intracellular signaling in innate immune pathways. Most studies of endogenous Pellino-2 have been performed in macrophages, but none in nonimmune cells. Using yeast two-hybrid ...

    • Pellino-2 intracellular localization and inflammasome overactivation in skin and corneal disease 

      Cristea, Ileana (Doctoral thesis, 2021-12-17)
      Background: Ocular pterygium-digital keloids dysplasia (OPDKD) is a rare, genetic disorder characterized by early onset corneal overgrowth and later development of keloids on distal limbs. We identified a de novo PELI2 ...

    • A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium–digital keloid dysplasia 

      Cristea, Ileana; Abarca, Hugo; Christensen, Anne Elisabeth; Trubnykova, Milana; Mehrasa, Roya; Peters, Dorien J. M.; Houge, Gunnar Douzgos; Hennekam, Raoul C. M.; Rødahl, Eyvind; Bruland, Ove; Bredrup, Cecilie (Journal article; Peer reviewed, 2023)
      Ocular pterygium–digital keloid dysplasia (OPDKD) is a rare hereditary disease characterized by corneal ingrowth of vascularized conjunctival tissue early in life. Later, patients develop keloids on fingers and toes but ...

    • Percutaneous cholecystostomy in acutecholecystitis; a retrospective analysis of a largeseries of 104 patients 

      Viste, Asgaut; Jensen, Dag Kjartan; Angelsen, Jon-Helge; Hoem, Dag (Peer reviewed; Journal article, 2015-03-08)
      Background: The purpose of this study was to evaluate the clinical course and possible benefit of a percutaneous cholecystostomy in patients with acute cholecystitis. Methods: Retrospective study of 104 patients with severe ...

    • Percutaneous cholecystostomy – An option in selected patients with acute cholecystitis 

      Søreide, Jon Arne; Fjetland, Anja Maria; Desserud, Kari Festøy; Greve, Ole Jacob; Fjetland, Lars (Journal article; Peer reviewed, 2020-05)
      While urgent percutaneous cholecystostomy (PC) was introduced as an alternative to acute surgical treatment for acute cholecystitis (AC), the current place of PC in the treatment algorithm for AC is challenged. We evaluate ...

    • Perinatal Depression and Anxiety in Women with Multiple Sclerosis: A Population-Based Cohort Study 

      Eid, Karine; Torkildsen, Øivind Fredvik Grytten; Aarseth, Jan Harald; Flemmen, Heidi Øyen; Holmøy, Trygve; Lorentzen, Åslaug Rudjord; Myhr, Kjell-Morten; Riise, Trond; Simonsen, Cecilia Smith; Torkildsen, Cecilie Fredvik; Wergeland, Stig; Willumsen, Johannes Sverre; Øksendal, Nina; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2021)
      Objective: To assess the occurrence of perinatal depression and anxiety in women before and after diagnosis of multiple sclerosis (MS). Methods: 114,629 pregnant women were included in the Norwegian Mother, Father and Child ...

    • Perioperative interventions and postoperative outcomes 

      Jammer, Ib (Doctoral thesis, 2015-11-05)
      Background: Postoperative complications are frequent causes of postoperative mortality. Such complications may also lead to a prolonged period with decreased functional and cognitive status. Perioperative care is a factor ...

    • Perioperative, short, and long-term mortality related to fixation in primary total hip arthroplasty: a study of 79,557 patients in the Norwegian Arthroplasty Register 

      Dale, Håvard; Børsheim, Sjur; Kristensen, Torbjørn; Fenstad, Anne Marie; Gjertsen, Jan-Erik; Hallan, Geir; Lie, Stein Atle; Furnes, Ove (Peer reviewed; Journal article, 2019-12-13)
      Background and purpose — There are reports on perioperative deaths in cemented total hip arthroplasty (THA), and THA revisions are associated with increased mortality. We compared perioperative (intraoperatively or within ...

    • Persistence of a pKPN3-like CTX-M-15-encoding IncFIIK plasmid in a Klebsiella pneumonia ST17 host during two years of intestinal colonization 

      Löhr, Iren Høyland; Hülter, Nils Fredrik; Bernhoff, Eva; Johnsen, Pål Jarle; Sundsfjord, Arnfinn; Naseer, Mohammed Umaer (Peer reviewed; Journal article, 2015-03-04)
      Objectives. To characterize the CTX-M-15-encoding plasmid in a Klebsiella pneumoniae ST17 strain, responsible for an outbreak at a Norwegian neonatal intensive care unit and subsequent colonization of affected children for ...

    • Persistent microembolic signals in the cerebral circulation on transcranial Doppler after intravenous sulfur hexafluoride microbubble infusion 

      Aarli, Sander Johan; Novotny, Vojtech; Thomassen, Lars; Kvistad, Christopher Elnan; Logallo, Nicola; Fromm, Annette (Peer reviewed; Journal article, 2020)
      Background and purpose: Microembolic signals (MES) are detectable by transcranial Doppler monitoring and associated with increased risk of first or recurrent ischemic stroke. MES detection can also illuminate stroke etiology ...

    • The personality profile of IPS employment specialists, and how it relates to job satisfaction: A longitudinal cohort study 

      Butenko, Daniil; Rinaldi, Miles; Brinchmann, Beate; Brandseth, Oda Lekve; Killackey, Eoin; Mykletun, Arnstein (Journal article; Peer reviewed, 2022)
      The role of the Individual Placement and Support (IPS) employment specialist is a new type of occupation within mental healthcare. High turnover among employment specialists necessitates improvement in their recruitment ...

    • Personality traits predict job stress, depression and anxiety among junior physicians 

      Gramstad, Thomas Olsen; Gjestad, Rolf; Haver, Brit (Peer reviewed; Journal article, 2013-11-09)
      Background: High levels of stress and deteriorating mental health among medical students are commonly reported. In Bergen, Norway, we explored the impact of personality traits measured early in their curriculum on stress ...

    • Personalized estimation of one-year mortality risk after elective hip or knee arthroplasty for osteoarthritis. 

      Trela-Larsen, L; Kroken, Gard; Bartz-Johannessen, Christoffer; Sayers, Adele; Aram, P; McCloskey, Eugene; Kadirkamanathan, V; Blom, A; Lie, Stein Atle; Furnes, Ove; Wilkinson, J. Mark (Journal article; Peer reviewed, 2020)
      Aims To develop and validate patient-centred algorithms that estimate individual risk of death over the first year after elective joint arthroplasty surgery for osteoarthritis. Methods A total of 763,213 hip and knee ...

    • The Pharmacogenomics of Bipolar Disorder study (PGBD): Identification of genes for lithium response in a prospective sample 

      Ødegaard, Ketil Joachim; Alda, Martin; Anand, Anit; Andreassen, Ole Andreas; Balaraman, Yokesh; Berrettini, Wade H.; Bhattacharjee, Abesh; Brennand, Kristen J.; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Claasen, Ana; Coryell, William H.; Craig, David; DeModena, Anna; Frye, Mark A.; Gage, Fred H.; Gao, Keming; Garnham, Julie; Gershon, Elliot; Jakobsen, Petter; Leckband, Susan G.; McCarthy, Michael J.; McInnis, Melvin G.; Maihofer, Adam X.; Mertens, Jerome; Morken, Gunnar; Nievergelt, Caroline M.; Nurnberger, John I.; Pham, Son; Schøyen, Helle Kristine; Shekhtman, Tatyana; Shilling, Paul D.; Szelinger, Szabolcs; Tarwater, Bruce; Yao, Jun; Zandi, Peter P.; Kelsoe, John R. (Peer reviewed; Journal article, 2016-05-05)
      Background: Bipolar disorder is a serious and common psychiatric disorder characterized by manic and depressive mood switches and a relapsing and remitting course. The cornerstone of clinical management is stabilization ...

    • Pharmacokinetics of epinephrine during cardiac arrest: A pilot study 

      Heradstveit, Bård Einar; Sunde, Geir Arne; Asbjørnsen, Helge; Aalvik, Rune; Wentzel-Larsen, Tore; Heltne, Jon-Kenneth (Journal article; Peer reviewed, 2023)
      Aim of the study: Epinephrine has been recommended for several decades for the treatment of cardiac arrest. However, although this potent medicament has a documented impact on the return of spontaneous circulation, it does ...