Browsing Department of Clinical Medicine by Title
Now showing items 166-185 of 2170
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Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology
(Journal article; Peer reviewed, 2021)Aging, genomic stress, and mitochondrial dysfunction are risk factors for neurodegenerative pathologies, such as Parkinson disease (PD). Although genomic instability is associated with aging and mitochondrial impairment, ... -
Baseline microvessel density predicts response to neoadjuvant bevacizumab treatment of locally advanced breast cancer
(Journal article; Peer reviewed, 2021)A subset of breast cancer patients benefits from preoperative bevacizumab and chemotherapy, but validated predictive biomarkers are lacking. Here, we aimed to evaluate tissue-based angiogenesis markers for potential ... -
BCG vaccination and multiple sclerosis risk: A Norwegian cohort study
(Journal article; Peer reviewed, 2024)Introduction: Bacillus Calmette–Guérin (BCG) vaccination induces long-lasting effects on the adaptive and innate immune systems and prevents development of experimental autoimmune encephalomyelitis and possibly also ... -
Behandling av motoriske symptomer ved Parkinsons sykdom
(Journal article; Peer reviewed, 2023)Gjennom de siste årene har nye terapimuligheter og økt kunnskap om gamle metoder ført til endringer i vår behandling av Parkinsons sykdom. Likevel åpner alle tilgjengelige norske og utenlandske terapianbefalinger for ulike ... -
Behavioral Inhibition and Social Anxiety Disorder as Predictors of Long-Term Outcomes of Cognitive Behavioral Therapy for Youth Anxiety Disorders
(Journal article; Peer reviewed, 2024)The temperamental trait behavioral inhibition (BI) is related to the development and maintenance of anxiety, particularly much so to social anxiety disorder. We investigated if BI and social anxiety disorder predicted ... -
Benchmarking of aggregated length of stay after open and laparoscopic surgery for cancers of the digestive system
(Peer reviewed; Journal article, 2018-08-01)Background: Length of hospital stay (LOS) may serve as a surrogate measure of healthcare quality and resource use, particularly when transfers of care and readmissions are accounted for. This study aimed to benchmark true ... -
Benefit from B-Lymphocyte Depletion Using the Anti- CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study
(Peer reviewed; Journal article, 2011-10-19)Background: Chronic fatigue syndrome (CFS) is a disease of unknown aetiology. Major CFS symptom relief during cancer chemotherapy in a patient with synchronous CFS and lymphoma spurred a pilot study of B-lymphocyte depletion ... -
Benign external hydrocephalus: a review, with emphasis on management
(Peer reviewed; Journal article, 2011-06-07)Benign external hydrocephalus in infants, characterized by macrocephaly and typical neuroimaging findings, is considered as a self-limiting condition and is therefore rarely treated. This review concerns all aspects of ... -
Benign paroxysmal positional vertigo and treatment in biaxial rotational chair
(Doctoral thesis, 2021-04-23)Benign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral dizziness. The overall aim of this thesis was to examine a new standardised intervention-tool to provide a better treatment for patients ... -
Benzodiazepines and antidepressants: Effects on cognitive and functional decline in Alzheimer's disease and Lewy body dementia
(Journal article; Peer reviewed, 2021-12-31)Objectives We aim to study the effects of the prescription of benzodiazepines and antidepressants on cognitive and functional decline in older adults living with Alzheimer's disease (AD) and Lewy body dementia (LBD) over ... -
Best Practice Recommendations for the Implementation of a Digital Pathology Workflow in the Anatomic Pathology Laboratory by the European Society of Digital and Integrative Pathology (ESDIP)
(Journal article; Peer reviewed, 2021)The interest in implementing digital pathology (DP) workflows to obtain whole slide image (WSI) files for diagnostic purposes has increased in the last few years. The increasing performance of technical components and the ... -
Better mental health in children of Vietnamese refugees compared with their Norwegian peers - a matter of cultural difference?
(Peer reviewed; Journal article, 2009-10-21)Background: There are conflicting results on whether immigrant children are at a heightened risk of mental health problems compared with native youth in the resettlement country. The objective of the study: To compare the ... -
Better survival of hybrid total knee arthroplasty compared to cemented arthroplasty.
(Peer reviewed; Journal article, 2015)Background and purpose — There have been few comparative studies on total knee replacement (TKR) with cemented tibia and uncemented femur (hybrid TKR). Previous studies have not shown any difference in revision rate between ... -
Bioavailability of iodine from a meal consisting of sushi and a wakame seaweed salad—A randomized crossover trial
(Journal article; Peer reviewed, 2023)The consumption of seaweed is on the rise in the Western world. Seaweeds may contain substantial amounts of iodine, and some species could serve as a potential dietary iodine source. However, limited data on the iodine ... -
Bioavailability of iron, zinc, folate and vitamin A when fortified in condiments and seasonings
(Peer reviewed; Journal article, 2015-11)Seasonings and condiments can be candidate vehicles for micronutrient fortification if consumed consistently and if dietary practices ensure bioavailability of the nutrient. In this review, we identify factors that may ... -
Biological Characteristics of Stem-Like Cells in Oral Squamous Cell Carcinoma
(Doctoral thesis, 2013-06-18)It has been shown that many solid malignancies, including oral squamous cell carcinoma (OSCC), contain a small population of tumorigenic cells referred to as cancer stem-like cells (CSCs) or tumor initiating cells (TICs). ... -
The biology of aging and cancer: A brief overview of shared and divergent molecular hallmarks
(Peer reviewed; Journal article, 2017-10)Aging is the inevitable time-dependent decline in physiological organ function and is a major risk factor for cancer development. Due to advances in health care, hygiene control and food availability, life expectancy is ... -
Biomarker and pathology studies in neurodegenerative cognitive impairment
(Doctoral thesis, 2019-10-16)Background: Dementia is a major cause of functional impairment and early death in older age groups. Neurodegenerative disorders are the most common cause of dementia. The most frequent neuropathological lesions include ... -
Biomarker profiles in serum and saliva of experimental Sjögren's syndrome: associations with specific autoimmune manifestations
(Peer reviewed; Journal article, 2008-02-20)Introduction Sjögren's syndrome (SS) is a systemic autoimmune disease that mainly targets the exocrine glands. The aim of this study was to investigate the involvement of 87 proteins measured in serum and 75 proteins ... -
Biomarker prognostication of cognitive impairment may be feasible even in out-of hospital cardical arrest survivors with good neurological outcome
(Journal article; Peer reviewed, 2021)Background Patients surviving out-of hospital cardicac arrest, with good neurological outcome according to Cerebral Performance Category, frequently have neuropsychological impairment. We studied whether biomarker data ...