Blar i Department of Clinical Medicine på tittel
Viser treff 241-260 av 2116
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CD47 and CD68 expression in breast cancer is associated with tumor-infiltrating lymphocytes, blood vessel invasion, detection mode, and prognosis
(Journal article; Peer reviewed, 2023)CD47 expressed on tumor cells binds to signal regulatory protein alpha on macrophages, initiating inhibition of phagocytosis. We investigated the relationships between tumor expression of CD47 and CD68 macrophage content, ... -
CDR2 antigen and Yo antibodies
(Peer reviewed; Journal article, 2011)Paraneoplastic cerebellar degeneration (PCD) is often associated with Yo antibodies that are directed against human cerebellar degeneration-related protein 2 (CDR2). Such antibodies may also be found in ovarian cancer ... -
CDR2L Is the Major Yo Antibody Target in Paraneoplastic Cerebellar Degeneration
(Peer reviewed; Journal article, 2019)The pathogenesis of Yo‐mediated paraneoplastic cerebellar degeneration (PCD) is unclear. We applied cerebrospinal fluid and serum from PCD patients as well as CDR2 and CDR2L antibodies to neuronal tissue, cancer cell lines, ... -
Cellular metabolism in colorectal carcinogenesis: Influence of lifestyle, gut microbiome and metabolic pathways
(Peer reviewed; Journal article, 2014-03-12)The interconnectivity between diet, gut microbiota and cell molecular responses is well known; however, only recently has technology allowed the identification of strains of microorganisms harbored in the gastrointestinal ... -
Cemented or uncemented hemiarthroplasty for femoral neck fracture? Data from the Norwegian Hip Fracture Register
(Journal article; Peer reviewed, 2020)Background A displaced femoral neck fracture in patients older than 70 years is a serious injury that influences the patient’s quality of life and can cause serious complications or death. Previous national guidelines ... -
Cementing technique for primary knee arthroplasty: a scoping review
(Peer reviewed; Journal article, 2019-08-27)Background and purpose - The optimal cementing technique for primary total knee arthroplasty (TKA) remains unclear. We therefore performed a scoping review based on available studies regarding cementation technique in ... -
Cementing techniques for total knee arthroplasty in Norwegian hospitals; a questionnaire-based study
(Journal article; Peer reviewed, 2023-11-18)Background: Cementing technique in total knee arthroplasty (TKA) may influence implant survival. There is limited knowledge about the results with clinically used techniques. The aim of this study was to investigate ... -
Centralizing a national pancreatoduodenectomy service: striking the right balance
(Journal article; Peer reviewed, 2020)Background Centralization of pancreatic surgery is currently called for owing to superior outcomes in higher-volume centres. Conversely, organizational and patient concerns speak for a moderation in centralization. Consensus ... -
A cerebellar degeneration-related protein 2-like cell-based assay for anti-Yo detection in patients with paraneoplastic cerebellar degeneration
(Journal article; Peer reviewed, 2023)Background and purpose Commercially available tests for Yo antibody detection have low specificity for paraneoplastic cerebellar degeneration (PCD) because these assays use cerebellar degeneration-related protein 2 (CDR2) ... -
Cerebellar degeneration-related proteins in anti-Yo associated paraneoplastic cerebellar degeneration
(Doctoral thesis, 2021-06-25)Background: Paraneoplastic neurological syndromes (PNS) are rare immune-mediated diseases triggered by cancer, and characterized by circulating onconeural antibodies directed against antigens expressed by neurons and tumor ... -
Cerebral magnetic resonance imaging in children with prenatal drug exposure. Structural and functional aspects of the opioid-exposed brain
(Doctoral thesis, 2018-02-02)Background: Over the last few decades brain imaging studies have made important contributions to our understanding of how prenatal drug exposure can impact normal brain development. The teratogenic potential of alcohol has ... -
Cerebrospinal fluid neurofilament light chain mediates age-associated lower learning and memory in healthy adults
(Journal article; Peer reviewed, 2023)Multiple cognitive domains, including learning, memory, and psychomotor speed, show significant reductions with age. Likewise, several cerebrospinal fluid (CSF) neurodegenerative biomarkers, including total tau (t-tau, a ... -
Challenges and possible solutions in cross-disciplinary and cross-sectorial research teams within the domain of e-mental health
(Journal article; Peer reviewed, 2021)Purpose: Mental illness presents a huge individual, societal and economic challenges, currently accounting for 20% of the worldwide burden of disease. There is a gap between the need for and access to services. Digital ... -
Chambered warm moist air eyelid warming devices – a review
(Journal article; Peer reviewed, 2021)Background Eyelid warming is an important treatment for meibomian gland dysfunction (MGD). Specialized chambered devices, using warm moist air have been developed. Purpose To critically evaluate the literature on the ... -
Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels
(Journal article; Peer reviewed, 2022)Purpose: To investigate the changes in the tear cytokine profile of patients with meibomian gland dysfunction (MGD) treated with eyelid warming and to correlate these changes with clinical parameters for dry eye disease ... -
Changes in colonic enteroendocrine cells of patients with irritable bowel syndrome following fecal microbiota transplantation
(Journal article; Peer reviewed, 2022)Objectives The aim was to investigate the effect of fecal microbiota transplantation (FMT) on colonic enteroendocrine cells densities in patients with irritable bowel syndrome (IBS). Materials and methods This study ... -
Changes in epidemiology and care strategies at the Norwegian National Burn Centre over 35 years (1986–2020)
(Journal article; Peer reviewed, 2023)Introduction: We evaluated trends in admissions, % TBSA (total body surface area) burnt, age, and outcomes over a 35-year period at the national burn centre in Norway. Methods: Relevant data were extracted from the ... -
Changes in fecal short-chain fatty acids following fecal microbiota transplantation in patients with irritable bowel syndrome
(Journal article; Peer reviewed, 2020)Background Short‐chain fatty acids (SCFAs) may play a role in the pathophysiology of irritable bowel syndrome (IBS). This study analyzed fecal SCFAs after performing fecal microbiota transplantation (FMT) in the IBS ... -
Changes in Immune Cell Types with Age in Breast are Consistent with a Decline in Immune Surveillance and Increased Immunosuppression
(Journal article; Peer reviewed, 2021)A majority of breast cancers (BC) are age-related and we seek to determine what cellular and molecular changes occur in breast tissue with age that make women more susceptible to cancer initiation. Immune-epithelial cell ... -
Changes in leg pain after bilateral fasciotomy to treat chronic compartment syndrome: a case series study
(Peer reviewed; Journal article, 2013-04-05)Background: Intracompartmental pressure (ICP) as the diagnostic gold standard in the management of chronic compartment syndrome (CCS) is debated. We present a diagnostic protocol in which the decision to operate can be ...