Blar i Department of Clinical Medicine på tittel
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Epidemiology of benign external hydrocephalus in Norway - a population-based study
(Peer reviewed; Journal article, 2017-08)Background: Benign external hydrocephalus is defined as a rapidly increasing head circumference (occipitofrontal circumference) with characteristic radiological findings of increased subarachnoid cerebrospinal fluid spaces ... -
Epidemiology of forearm fractures in women and men in Norway 2008–2019
(Journal article; Peer reviewed, 2023)Summary The purpose of this paper is to describe rates of forearm fractures in adults in Norway 2008–2019. Incidence rate of distal forearm fractures declined over time in both sexes. Forearm fracture constitute a ... -
Epidemiology, comorbidity and clinical course of myasthenia gravis. A registry-based study
(Doctoral thesis, 2016-01-22)Background: Autoimmune myasthenia gravis (MG) is a rare neuromuscular transmission disorder. The pathophysiologic mechanisms are well-studied, but the etiology remains unknown. The clinical course of MG is still characterized ... -
Epidemiology, treatment and outcome of out-of-hospital cardiac arrest
(Doctoral thesis, 2015-03-26)Introduction: Every year in the Western world, emergency medical system (EMS) personnel attempt to resuscitate approximately 500,000 patients who experience out of the hospital cardiac arrest (OHCA). Reported incidences ... -
Epithelial PD-L1 expression at tumor front predicts overall survival in a cohort of oral squamous cell carcinomas from Sudan
(Journal article; Peer reviewed, 2022)Background We recently described the tumor immune microenvironment (TIME) in oral squamous cell carcinomas (OSCC) from Sudan by assessing the core of the lesions. However, the invasive tumor front (ITF) is the most active ... -
Epithelial to Mesenchymal Transition of a Primary Prostate Cell Line with Switches of Cell Adhesion Modules but without Malignant Transformation
(Peer reviewed; Journal article, 2008-10-13)Background: Epithelial to mesenchymal transition (EMT) has been connected with cancer progression in vivo and the generation of more aggressive cancer cell lines in vitro. EMT has been induced in prostate cancer cell lines, ... -
Epithelial-to-mesenchymal transition in clear cell renal cell cancer and renal fibrosis
(Doctoral thesis, 2019-01-16)Background: Clear cell renal cell cancer (ccRCC) is a common cancer in humans and still has a high mortality. Chronic kidney disease (CKD) is a worldwide public health issue due to its increasing incidence and high morbidity ... -
The epithelial–mesenchymal transition regulators Twist, Slug, and Snail are associated with aggressive tumour features and poor outcome in prostate cancer patients
(Journal article; Peer reviewed, 2021)The prognostic importance of transcription factors promoting epithelial–mesenchymal transition (EMT) and angiogenesis has not been well explored in prostate cancer patients with long follow-up, nor the interplay between ... -
Er angst, apati og kognitiv sviktprofil assosiert med sykdomsprogresjon ved mild demens? Med hovedfokus på demens med Lewylegemer
(Doctoral thesis, 2018-10-12)Background Dementia is a major public health problem in all parts of the world, and due to an aging population, the prevalence of dementia is growing. Two of the most frequent forms of dementias are Alzheimer`s disease ... -
Ernæringsstatus hos voksne pasienter med inflammatorisk tarmsykdom som får biologisk behandling ved Sørlandet sykehus
(Master thesis, 2018-06-22)Rationale: Patients with inflammatory bowel disease (IBD) belong to a high-risk group for malnutrition [1]. The aim was to evaluate if «Nutritional Risk Screening 2002» (NRS 2002) detects patients at nutritional risk, and ... -
Erosion or normal variant? 4-year MRI follow-up of the wrists in healthy children
(Journal article; Peer reviewed, 2016)Background A large proportion of healthy children have wrist changes on MRI, namely carpal depressions, findings that have been described as pathological in children with juvenile idiopathic arthritis. Objective We ... -
Errors in medicine: punishment versus learning medical adverse events revisited - expanding the frame
(Journal article; Peer reviewed, 2023)Purpose of review : Despite healthcare workers’ best intentions, some patients will suffer harm and even death during their journey through the healthcare system. This represents a major challenge, and many solutions have ... -
Esophageal perforation: Diagnostic work-up and clinical decision-making in the first 24 hours
(Peer reviewed; Journal article, 2011-10-30)Abstract Esophageal perforation is a rare and potentially life-threatening condition. Early clinical suspicion and imaging is important for case management to achieve a good outcome. However, recent studies continue to ... -
The ESSO core curriculum committee update on surgical oncology
(Journal article; Peer reviewed, 2021)Introduction Surgical oncology is a defined specialty within the European Board of Surgery within the European Union of Medical Specialists (UEMS). Variation in training and specialization still occurs across Europe. There ... -
Establishing quality indicators for prehospital advanced airway management: a modified nominal group technique consensus process
(Journal article; Peer reviewed, 2021)Background: Prehospital advanced airway management is a complex intervention composed of numerous steps, interactions, and variables that can be delivered to a high standard in the prehospital setting. Standard research ... -
Establishing reliable MR spectroscopy techniques for measuring GABA and Glutathione in the human brain
(Doctoral thesis, 2018-05-03)Background: Proton MR spectroscopy (MRS) is a well-established method for measuring the relative concentration of a wide range of metabolites in the human brain noninvasively. Lately, more advanced spectroscopic techniques, ... -
Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds.
(Peer reviewed; Journal article, 2015)Background: Microenvironmental cues play a major role in head and neck cancer. Biodegradable scaffolds used for bone regeneration might also act as stimulative cues for head and neck cancer. The purpose of this study was ... -
Establishment of a novel cancer cell line derived from vulvar carcinoma associated with lichen sclerosus exhibiting a fibroblast-dependent tumorigenic potential
(Journal article; Peer reviewed, 2020)Vulvar squamous cell carcinoma associated with lichen sclerosus (VLS-VSCC) are rare tumors but with higher recurrence and worse prognosis than other types of VSCC. Lack of experimental models has limited the search for ... -
Estimation of Preanalytical Uncertainty in Clinical Chemistry
(Doctoral thesis, 2013-05-27)Preanalytical uncertainty is attributable to variations in blood sample collection and sample handling before analysis. The aim of this study was to establish a modelling framework for estimating preanalytical uncertainty. ... -
Estradiol measurement in translational studies of breast cancer
(Peer reviewed; Journal article, 2015-07)Plasma estrogen measurement with use of radioimmunoassays has been instrumental in the development of aromatase inhibitors for endocrine therapy of postmenopausal breast cancer. However, due to low plasma estrogen ...