Blar i Department of Clinical Medicine på tittel
Viser treff 693-712 av 2065
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Establishing reliable MR spectroscopy techniques for measuring GABA and Glutathione in the human brain
(Doctoral thesis, 2018-05-03)Background: Proton MR spectroscopy (MRS) is a well-established method for measuring the relative concentration of a wide range of metabolites in the human brain noninvasively. Lately, more advanced spectroscopic techniques, ... -
Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds.
(Peer reviewed; Journal article, 2015)Background: Microenvironmental cues play a major role in head and neck cancer. Biodegradable scaffolds used for bone regeneration might also act as stimulative cues for head and neck cancer. The purpose of this study was ... -
Establishment of a novel cancer cell line derived from vulvar carcinoma associated with lichen sclerosus exhibiting a fibroblast-dependent tumorigenic potential
(Journal article; Peer reviewed, 2020)Vulvar squamous cell carcinoma associated with lichen sclerosus (VLS-VSCC) are rare tumors but with higher recurrence and worse prognosis than other types of VSCC. Lack of experimental models has limited the search for ... -
Estimation of Preanalytical Uncertainty in Clinical Chemistry
(Doctoral thesis, 2013-05-27)Preanalytical uncertainty is attributable to variations in blood sample collection and sample handling before analysis. The aim of this study was to establish a modelling framework for estimating preanalytical uncertainty. ... -
Estradiol measurement in translational studies of breast cancer
(Peer reviewed; Journal article, 2015-07)Plasma estrogen measurement with use of radioimmunoassays has been instrumental in the development of aromatase inhibitors for endocrine therapy of postmenopausal breast cancer. However, due to low plasma estrogen ... -
Ethical challenges in nursing homes - staff's opinions and experiences with systematic ethics meetings with participation of residents' relatives.
(Peer reviewed; Journal article, 2015-04-28)Background Many ethical problems exist in nursing homes. These include, for example, decision-making in end-of-life care, use of restraints and a lack of resources. Aims The aim of the present study was to investigate ... -
Ethical challenges, decision-making and end-of-life care in nursing homes
(Doctoral thesis, 2017-02-13)Background: Many nursing home residents suffer from multimorbidity, frailty and dementia. A number of ethical challenges are connected to living and dying in nursing homes. Objective/purpose: This thesis investigates ethical ... -
European Burns Association guidelines for the management of burn mass casualty incidents within a European response plan
(Journal article; Peer reviewed, 2023)Background: A European response plan to burn mass casualty incidents has been jointly developed by the European Commission and the European Burn Association. Upon request for assistance by an affected country, the plan ... -
A European multicenter study on systematic ethics work in nursing homes
(Peer reviewed; Journal article, 2016)Background: There are many existing ethical challenges in nursing homes. Although different methods and approaches to discussing the ethical challenges have been established, systematic ethics work is not yet a standard ... -
European neuroborreliosis: Long term follow-up
(Doctoral thesis, 2012-06-15)Lyme disease is the most common human tick borne disease in the northern hemisphere, and the southern coastline of Norway is a high endemic region regarding Lyme disease. European Lyme neuroborreliosis (LNB) often presents ... -
European neuroborreliosis: neuropsychological findings 30 months post-treatment
(Peer reviewed; Journal article, 2011)Background: The aim of this study was to compare neuropsychological (NP) functioning in patients with Lyme neuroborreliosis (LNB) 30 months after treatment to matched controls. Methods: We tested 50 patients with LNB and ... -
European Society of Paediatric Radiology 2019 strategic research agenda: improving imaging for tomorrow’s children
(Peer reviewed; Journal article, 2019)The European Society of Paediatric Radiology (ESPR) research committee was established to initiate, drive forward and foster excellence in paediatric imaging, paediatric image-guided intervention and radiation protection ... -
European Society of Paediatric Radiology Artificial Intelligence taskforce: a new taskforce for the digital age
(Journal article; Peer reviewed, 2022)A new task force dedicated to artificial intelligence (AI) with respect to paediatric radiology was created in 2021 at the International Paediatric Radiology (IPR) meeting in Rome, Italy (a joint society meeting by the ... -
EUS-guided gastroenterostomy with a lumen apposing self-expandable metallic stent relieves gastric outlet obstruction–a Scandinavian case series
(Journal article; Peer reviewed, 2021)Background: EUS-guided gastroenterostomy (EUS-GE) with lumen-apposing metallic stents (LAMS) in patients with gastric outlet obstruction (GOO) has proven to be an alternative to luminal stenting in the duodenum and surgical ... -
Evaluation of a guided self-help intervention for irritable bowel syndrome - An interdisciplinary approach
(Master thesis, 2017-12-16)Background: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, defined by recurrent abdominal pain or discomfort, associated with defecation and/or altered bowel habits. Due to the lack ... -
Evaluation of a new e-learning framework for teaching nuclear medicine and radiology to undergraduate medical students
(Peer reviewed; Journal article, 2019)Background: Radiology and nuclear medicine have traditionally been taught in a series of lectures and seminars concluded by an examination testing knowledge rather than skills. Purpose: To emphasize skills in the students’ ... -
Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study)
(Peer reviewed; Journal article, 2011-02-04)<b>Background:</b> Chronic hyperglycemia confers increased risk for long-term diabetes-associated complications and repeated hemoglobin A1c (HbA1c) measures are a widely used marker for glycemic control in diabetes treatment ... -
Evaluation of Ki67 expression across distinct categories of breast cancer specimens: A Population-based study of matched surgical specimens, core needle biopsies and tissue microarrays
(Peer reviewed; Journal article, 2014-11-06)Introduction: Tumor cell proliferation in breast cancer is strongly prognostic and may also predict response to chemotherapy. However, there is no consensus on counting areas or cut-off values for patient stratification. ... -
Evaluation of nutritional status and methods to identify nutritional risk in rheumatoid arthritis and spondyloarthritis
(Journal article; Peer reviewed, 2020-11-21)Patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA) experience several nutritional challenges and are prone to develop malnutrition. This observational study aimed to perform a comprehensive nutritional ... -
Evaluation of potential reference genes for real time RT-PCR studies in Atlantic halibut (Hippoglossus Hippoglossus L.); during development, in tissues of healthy and NNV-injected fish, and in anterior kidney leucocytes
(Peer reviewed; Journal article, 2010-05-11)Background: Real time RT-PCR has become an important tool for analyzing gene expression in fish. Although several housekeeping genes have been evaluated in Atlantic halibut (Hippoglossus Hippoglossus L.), appropriate ...