Blar i Department of Clinical Science på tittel
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Formulering av kortisonpreparat til bruk ved binyrebarksvikt
(Master thesis, 2008-06-01) -
Forskningsveiledning - en av de essensielle faktorene på «veien til doktorgrad»
(Peer reviewed; Journal article, 2013)The journey to finish a PhD thesis is a long race, and several factors may play important roles in this process. A good working relationship between the supervisor and the candidate is an essential component for achieving ... -
Forskrivningspraksis av psykofarmaka i barne- og ungdomspsykiatri
(Master thesis, 2021-05-20)Bakgrunn: Riktig legemiddelbruk hos barn og unge er et viktig innsatsområde for å styrke kvalitet av behandling og pasientsikkerhet. Forskrivning av medikamenter til barn og unge er et utfordrende terapiområde i barne- og ... -
Fotokjemisk internalisering (PCI) av HER2-rettet immunotoksin; trastuzumab-saporin
(Master thesis, 2009-05-19)En begrensning for terapeutisk nytte av makromolekyler som utøver sin effekt intracellulært er at de etter opptak ved endocytose degraderes lysosomalt før de når sitt terapeutiske mål i cytosol. Fotokjemisk internalisering ... -
Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer’s Disease
(Peer reviewed; Journal article, 2019)Introduction: The aim of the study is to describe the frequency of frailty in people with a new diagnosis of mild dementia due to Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). Methods: This is a secondary ... -
The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy Indian adolescents
(Peer reviewed; Journal article, 2014-07-03)Background: QuantiFERON-TB Gold In-Tube (QFT) is an IFNγ-release assay used in the diagnosis of Mycobacterium tuberculosis (MTB) infection. The risk of TB progression increases with the magnitude of the MTB-specific ... -
Frequency and prognostic implications of orthostatic hypotension and white matter hyperintensities in older people with mild dementia
(Doctoral thesis, 2014-09-19)Background: In addition to cognitive impairments, dementia sufferers may have other problems as well, such as depression and orthostatic hypotension (OH), both of which according to previous studies may be associated with ... -
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
(Peer reviewed; Journal article, 2015)Mitochondrial genomes are separated from the nuclear genome for most of the cell cycle by the nuclear double membrane, intervening cytoplasm, and the mitochondrial double membrane. Despite these physical barriers, we show ... -
Friedreich ataxia in Norway - An epidemiological, molecular and clinical study Rare neurological diseases
(Peer reviewed; Journal article, 2015-09-04)Background: Friedreich ataxia is an autosomal recessive hereditary spinocerebellar disorder, characterized by progressive limb and gait ataxia due to proprioceptive loss, often complicated by cardiomyopathy, diabetes and ... -
Fucosylated AGP glycopeptides as biomarkers of HNF1A-Maturity onset diabetes of the young
(Journal article; Peer reviewed, 2022)Aims: We previously demonstrated that antennary fucosylated N-glycans on plasma proteins are regulated by HNF1A and can identify cases of Maturity-Onset Diabetes of the Young caused by HNF1A variants (HNF1A-MODY). Based ... -
Fueling the flames of colon cancer – does CRP play a direct pro-inflammatory role?
(Journal article; Peer reviewed, 2023-03-17)Background: Systemic inflammation, diagnostically ascribed by measuring serum levels of the acute phase reactant C-reactive protein (CRP), has consistently been correlated with poor outcomes across cancer types. CRP exists ... -
Function and regulation of Steroid Receptor Coactivator 2. Transcriptional regulation of cellular metabolism
(Doctoral thesis, 2015-12-18)Nuclear hormone receptors (NRs) associate with coregulators to enable complex programs of gene expression. The p160 steroid receptor coactivator 2 (SRC- 2/GRIP1) regulates metabolism and cellular processes in a tissue-specific ... -
Functional analyses of BRCA1 variants of unknown significance found in hereditary breast or ovarian cancer families in Norway: A tool for improved diagnosis
(Doctoral thesis, 2023-03-21)Tumorsuppressorgenet BRCA1 speler mange viktige roller for å hindre tumorutvikling, og endringar i BRCA1-genet er ei av hovudårsakene til arveleg bryst- og eggstokk-kreft (HBOC). I artikkel I vart det laga ei oversikt over ... -
Functional Analyses of Rare Germline Missense BRCA1 Variants Located within and outside Protein Domains with Known Functions
(Journal article; Peer reviewed, 2023-01-19)The BRCA1 protein is implicated in numerous important cellular processes to prevent genomic instability and tumorigenesis, and pathogenic germline variants predispose carriers to hereditary breast and ovarian cancer (HBOC). ... -
Functional analysis of tilS homologues in Bacteria and Archaea
(Master thesis, 2005-09-09)Out of all of the microorganisms sequenced so far about one third of the genes have unknown function. Several studies have shown that information on evolutionary relationships between unknown genes can aid in the prediction ... -
Functional and Binding H1N1pdm09-Specific Antibody Responses in Occasionally and Repeatedly Vaccinated Healthcare Workers: A Five-Year Study (2009-2014)
(Journal article; Peer reviewed, 2021)Background: In 2009, a novel influenza A/H1N1pdm09 emerged and caused a pandemic. This strain continued to circulate and was therefore included in the seasonal vaccines up to the 2016/2017-season. This provided a unique ... -
Functional characterization of genetic risk factors in autoimmune Addison’s disease
(Doctoral thesis, 2020-10-23)Autoimmune diseases occur when the immune system attacks and damages the body’s own tissue. Why people develop these diseases, and how the autoimmune reaction develops are unanswered questions. Autoimmune Addison's disease ... -
Functional studies of novel CYP21A2 mutations detected in Norwegian patients with congenital adrenal hyperplasia
(Peer reviewed; Journal article, 2014)In about 95% of cases, congenital adrenal hyperplasia (CAH) is caused by mutations in CYP21A2 gene encoding steroid 21-hydroxylase (21OH). Recently, we have reported four novel CYP21A2 variants in the Norwegian population ... -
Functional toll-like receptors (TLRs) are expressed by a majority of primary human acute myeloid leukemia cells and inducibility of the TLR signaling pathway is associatedwith a more favorable phenotype
(Peer reviewed; Journal article, 2019-07-11)Acute myeloid leukemia (AML) is a highlyheterogeneous disease withregardto biological characteristics and receptor expression. Toll-like receptors (TLRs) are upstream to the transcription factor NFκB and part of the innate ... -
Fysisk aktivitet og astma blant barn og ungdommer i Bergen – RHINESSA-studien
(Master thesis, 2020-06-19)En stor andel av barn og unge i Norge har den kroniske lungesykdommen astma og behandles med astmamedikamenter for dette. Samtidig viser rapporten «Kartlegging av fysisk aktivitet, sedat tid og fysisk form blant barn og ...