Blar i Department of Clinical Science på tittel

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    • Octogenarian patients’ sleep and delirium experiences in hospital and four years after aortic valve replacement: a qualitative interview study 

      Amofah, Hege Andersen; Broström, Anders; Instenes, Irene; Fridlund, Bengt; Haaverstad, Rune; Kuiper, Karel Kier-Jan; Ranhoff, Anette Hylen; Norekvål, Tone Merete (Journal article; Peer reviewed, 2021)
      Objectives Sleep disturbances and delirium are frequently observed complications after surgical aortic valve replacement (SAVR) and transcutaneous aortic valve implantation (TAVI), especially in octogenarian patients. ...

    • Olaparib monotherapy as primary treatment in unselected triple negative breast cancer 

      Eikesdal, Hans Petter; Yndestad, Synnøve; Elzawahry, Asmaa; Llop-Guevara, Alba; Gilje, Bjørnar; Blix, Egil Støre; Espelid, Helge; Lundgren, Steinar; Geisler, Jürgen; Vagstad, Geirfinn; Venizelos, Andreas; Minsaas, Laura; Leirvaag, Beryl; Gudlaugsson, Einar; Vintermyr, Olav Karsten; Aase, Hildegunn Siv; Aas, Turid; Balmaña, Judith; Serra, Violeta; Janssen, Emiel; Knappskog, Stian; Lønning, Per Eystein (Journal article; Peer reviewed, 2020)
      Background The antitumor efficacy of PARP inhibitors (PARPi) for breast cancer patients harboring germline BRCA1/2 (gBRCA1/2) mutations is well established. While PARPi monotherapy was ineffective in patients with metastatic ...

    • Older patients’ perspectives on illness and healthcare during the early phase of the COVID-19 pandemic 

      Jøranson, Nina; Heggestad, Anne Kari Tolo; Lausund, Hilde; Breievne, Grete; Bruun-Olsen, Vigdis; Heiberg, Kristi Elisabeth; Myrstad, Marius; Ranhoff, Anette Hylen (Journal article; Peer reviewed, 2022)
      Background Equal access to healthcare is a core principle in Norway’s public healthcare system. The COVID-19 pandemic challenged healthcare systems in the early phase – in particular, related to testing and hospital ...

    • On the importance of parenting in externalizing disorders: an evaluation of indirect genetic effects in families 

      Eilertsen, Espen Moen; Gillespie Cheesman, Rosa Catherine; Ayorech, Ziada; Røysamb, Espen; Pingault, Jean-Baptiste; Njølstad, Pål Rasmus; Andreassen, Ole; Havdahl, Alexandra Karoline Saasen; McAdams, Tom A.; Torvik, Fartein Ask; Ystrøm, Eivind (Journal article; Peer reviewed, 2022)
      Background: Theoretical models of the development of childhood externalizing disorders emphasize the role of parents. Empirical studies have not been able to identify specific aspects of parental behaviors explaining a ...

    • One-year impact of bariatric surgery on left ventricular mechanics: results from the prospective FatWest study 

      Grymyr, Lisa Marie Dale; Nadirpour, Saied; Gerdts, Eva; Nedrebø, Bjørn Gunnar; Hjertaas, Johannes Just; Matre, Knut; Cramariuc, Dana (Journal article; Peer reviewed, 2021)
      Aims Patients with severe obesity are predisposed to left ventricular (LV) hypertrophy, increased myocardial oxygen demand, and impaired myocardial mechanics. Bariatric surgery leads to rapid weight loss and improves ...

    • One-Year Treatment with Olanzapine Depot in Female Rats: Metabolic Effects 

      Ersland, Kari Merete; Myrmel, Lene Secher; Fjære, Even; Berge, Rolf Kristian; Madsen, Lise; Steen, Vidar Martin; Skrede, Silje (Peer reviewed; Journal article, 2019-05)
      Background: Antipsychotic drugs can negatively affect the metabolic status of patients, with olanzapine as one of the most potent drugs. While patients are often medicated for long time periods, experiments in rats typically ...

    • Oocyst Shedding Dynamics in Children with Cryptosporidiosis: a Prospective Clinical Case Series in Ethiopia 

      Johansen, Øystein Haarklau; Abdissa, Alemseged; Bjørang, Ola; Zangenberg, Mike; Sharew, Bizuwarek; Alemu, Yonas; Moyo, Sabrina John; Mekonnen, Zeleke; Langeland, Nina; Robertson, Lucy; Hanevik, Kurt (Journal article; Peer reviewed, 2022)
      Knowledge on the duration of Cryptosporidium oocyst shedding, and how shedding may be affected by subtypes and clinical parameters, is limited. Reduced transmission may be a secondary benefit of cryptosporidiosis treatment ...

    • Operator radiation exposure in cardiac catheterization   

      Davidsen, Cedric (Doctoral thesis, 2024-03-22)
      Introduksjon Røntgenveiledete hjerteprosedyrer utsetter både pasient og operatør for ioniserende stråling. Selv om operatørdosen er en brøkdel av pasientdosen, kan en operatør utføre tusenvis av prosedyrer i løpet av en ...

    • Opptak av legemiddelanamnese ved innleggelse på sykehus 

      Brøndbo, Inga Aftret (Master thesis, 2011-05-20)
      Uheldige hendelser som følge av feil legemiddelbruk forårsaker årlig et betydelig antall dødsfall, invalidiserende skader og ekstra liggedøgn i sykehus. Halvparten av hendelsene kan forebygges. En stor andel feil skjer ved ...

    • Optic nerve constraints for carbon ion RT at CNAO ? Reporting and relating outcome to European and Japanese RBE 

      Dale, Jon Espen; Molinelli, Silvia; Vitolo, Viviana; Vischioni, Barbara; Bonora, Maria; Magro, Giuseppe; Pettersen, Helge Egil Seime; Mairani, Andrea; Hasegawa, Azusa; Dahl, Olav; Valvo, Francesca; Fossati, Piero (Peer reviewed; Journal article, 2019)
      Background and purpose: Until now, carbon ion RT (CIRT) dose constraints for the optic nerve (ON) have only been validated and reported in the NIRS RBE-weighted dose (DNIRS). The aim of this work is to improve CNAO’s ...

    • The optimal cut-off values for tumor size, number of lesions, and CEA levels in patients with surgically treated colorectal cancer liver metastases: An international, multi-institutional study 

      Kamphues, Carsten; Andreatos, Nikolaos; Kruppa, Jochen; Buettner, Stefan; Wang, Jaeyun; Sasaki, Kazunari; Wagner, Doris; Morioka, Daisuke; Fitschek, Fabian; Løes, Inger Marie; Imai, Katsunori; Sun, Jinger; Poultsides, George; Kaczirek, Klaus; Lønning, Per Eystein; Endo, Itaru; Baba, Hideo; Kornprat, Peter; Aucejo, Federico N.; Wolfgang, Christopher L.; Kreis, Martin E.; Weiss, Matthew J.; Margonis, Georgios Antonios (Journal article; Peer reviewed, 2021)
      Background and Objectives Despite the long-standing consensus on the importance of tumor size, tumor number and carcinoembryonic antigen (CEA) levels as predictors of long-term outcomes among patients with colorectal liver ...

    • Optimization of bacterial DNA and endotoxin extraction from settled airborne dust 

      Abouelhana, Hesham Amin Mohamed; Marshall, Ian P.G.; Bertelsen, Randi Jacobsen; Wouters, Inge M.; Schlünssen, Vivi; Sigsgaard, Torben; Šantl-Temkiv, Tina (Journal article; Peer reviewed, 2023)
      Collecting and obtaining sufficient amount of airborne particles for multiple microbial component assessments can be challenging. A passive dust sampling device, the electrostatic dust fall collector (EDC) has been established ...

    • An optimized multiplex flow cytometry protocol for the analysis of intracellular signaling in peripheral blood mononuclear cells 

      Davies, Richard Allan; Vogelsang, Petra; Jonsson, Roland; Appel, Silke (Peer reviewed; Journal article, 2016-09)
      Phosphoflow cytometry is increasingly being used as a tool for the discovery of biomarkers used in the treatment and monitoring of disease and therapy. The ability to measure numerous phospho-protein targets simultaneously ...

    • Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non-adherent to CPAP 

      Gjerde, Kjersti; Lehmann, Sverre; Berge, Morten Eirik; Johansson, Ann-Katrin Gerd; Johansson, Anders (Peer reviewed; Journal article, 2015-12-27)
      The aim of this retrospective study was to evaluate the effect of individually adjusted custom-made mandibular advancement device/oral appliance (OA) in treatment of patients with moderate and severe obstructive sleep ...

    • Oral health-related interdisciplinary practices among healthcare professionals in Saudi Arabia: Does integrated care exist? 

      Gaffar, Balgis; Farooqi, Faraz Ahmed; Nazir, Muhammad Ashraf; Bakhurji, Eman; Al-Khalifa, Khalifa S.; Alhareky, Muhanad; Virtanen, Jorma (Journal article; Peer reviewed, 2022)
      Background There is a bidirectional relation between oral and general health, therefore collaboration between healthcare providers is needed. This study investigated current interdisciplinary practices (IDP) and the ...

    • Oral microbiota in autoimmune polyendocrine syndrome type 1 

      Bruserud, Øyvind; Siddiqui, Huma; Marthinussen, Michaela Cuida; Chen, Tsute; Jonsson, Roland; Oftedal, Bergithe Eikeland; Olsen, Ingar; Husebye, Eystein Sverre; Wolff, Anette Bøe (Peer reviewed; Journal article, 2018)
      Background: Autoimmune polyendocrine syndrome type-1 (APS-1) is a rare, childhood onset disease caused by mutations in the Autoimmune Regulator gene. The phenotypic expression is highly variable and includes disease ...

    • An organellar Nα-acetyltransferase, Naa60, acetylates cytosolic n termini of transmembrane proteins and maintains golgi integrity 

      Aksnes, Henriette; Van Damme, Petra; Goris, Marianne; Starheim, Kristian K.; Marie, Michael Bruno Eric; Støve, Svein Isungset; Hoel, Camilla; Kalvik, Thomas Vikestad; Hole, Kristine; Glomnes, Nina; Furnes, Clemens; Ljostveit, Sonja; Ziegler, Mathias; Niere, Marc; Gevaert, Kris; Arnesen, Thomas (Peer reviewed; Journal article, 2015-02-26)
      N-terminal acetylation is a major and vital protein modification catalyzed by N-terminal acetyltransferases (NATs). NatF, or Nα-acetyltransferase 60 (Naa60), was recently identified as a NAT in multicellular eukaryotes. ...

    • Organizational structures influencing timely recognition and acknowledgment of end-of-life in hospitals – A qualitative study of nurses' and doctors’ experiences 

      Bakken, Janet; Wallgren, Gry Ciekals; Furnes, Bodil; Kørner, Hartwig; Ueland, Venke Irene (Journal article; Peer reviewed, 2023)
      Purpose Healthcare personnel's timely recognition and acknowledgment of end-of-life (EOL) is fundamental for reducing futile treatment, enabling informed decisions regarding the last days or weeks of life, and focusing ...

    • Our genes, our selves: hereditary breast cancer and biological citizenship in Norway 

      Solbrække, Kari Nyheim; Søiland, Håvard; Lode, Kirsten; Gripsrud, Birgitta Haga (Peer reviewed; Journal article, 2017-03)
      In this paper we explore the rise of ‘the breast cancer gene’ as a field of medical, cultural and personal knowledge. We address its significance in the Norwegian public health care system in relation to so-called biological ...

    • Outcome after rewarming from accidental hypothermia by use of extracorporeal circulation 

      Svendsen, Øyvind Sverre; Grong, Ketil; Andersen, Knut Sverre; Husby, Paul (Peer reviewed; Journal article, 2017)
      Background: Accidental hypothermia with arrested circulation remains a condition associated with high mortality. In our institution, extracorporeal circulation (ECC) rewarming has been the cornerstone in treating such ...