Blar i Department of Clinical Science på tittel
Viser treff 1569-1588 av 2310
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The optimal cut-off values for tumor size, number of lesions, and CEA levels in patients with surgically treated colorectal cancer liver metastases: An international, multi-institutional study
(Journal article; Peer reviewed, 2021)Background and Objectives Despite the long-standing consensus on the importance of tumor size, tumor number and carcinoembryonic antigen (CEA) levels as predictors of long-term outcomes among patients with colorectal liver ... -
Optimization of bacterial DNA and endotoxin extraction from settled airborne dust
(Journal article; Peer reviewed, 2023)Collecting and obtaining sufficient amount of airborne particles for multiple microbial component assessments can be challenging. A passive dust sampling device, the electrostatic dust fall collector (EDC) has been established ... -
An optimized multiplex flow cytometry protocol for the analysis of intracellular signaling in peripheral blood mononuclear cells
(Peer reviewed; Journal article, 2016-09)Phosphoflow cytometry is increasingly being used as a tool for the discovery of biomarkers used in the treatment and monitoring of disease and therapy. The ability to measure numerous phospho-protein targets simultaneously ... -
Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non-adherent to CPAP
(Peer reviewed; Journal article, 2015-12-27)The aim of this retrospective study was to evaluate the effect of individually adjusted custom-made mandibular advancement device/oral appliance (OA) in treatment of patients with moderate and severe obstructive sleep ... -
Oral health-related interdisciplinary practices among healthcare professionals in Saudi Arabia: Does integrated care exist?
(Journal article; Peer reviewed, 2022)Background There is a bidirectional relation between oral and general health, therefore collaboration between healthcare providers is needed. This study investigated current interdisciplinary practices (IDP) and the ... -
Oral microbiota in autoimmune polyendocrine syndrome type 1
(Peer reviewed; Journal article, 2018)Background: Autoimmune polyendocrine syndrome type-1 (APS-1) is a rare, childhood onset disease caused by mutations in the Autoimmune Regulator gene. The phenotypic expression is highly variable and includes disease ... -
An organellar Nα-acetyltransferase, Naa60, acetylates cytosolic n termini of transmembrane proteins and maintains golgi integrity
(Peer reviewed; Journal article, 2015-02-26)N-terminal acetylation is a major and vital protein modification catalyzed by N-terminal acetyltransferases (NATs). NatF, or Nα-acetyltransferase 60 (Naa60), was recently identified as a NAT in multicellular eukaryotes. ... -
Organizational structures influencing timely recognition and acknowledgment of end-of-life in hospitals – A qualitative study of nurses' and doctors’ experiences
(Journal article; Peer reviewed, 2023)Purpose Healthcare personnel's timely recognition and acknowledgment of end-of-life (EOL) is fundamental for reducing futile treatment, enabling informed decisions regarding the last days or weeks of life, and focusing ... -
Our genes, our selves: hereditary breast cancer and biological citizenship in Norway
(Peer reviewed; Journal article, 2017-03)In this paper we explore the rise of ‘the breast cancer gene’ as a field of medical, cultural and personal knowledge. We address its significance in the Norwegian public health care system in relation to so-called biological ... -
Outcome after rewarming from accidental hypothermia by use of extracorporeal circulation
(Peer reviewed; Journal article, 2017)Background: Accidental hypothermia with arrested circulation remains a condition associated with high mortality. In our institution, extracorporeal circulation (ECC) rewarming has been the cornerstone in treating such ... -
Outcomes following PDA surgery in extremely preterm born subjects. Focusing on left vocal cord paralysis and associated short- and long-tem outcomes
(Doctoral thesis, 2022-06-14)Background: Extremely preterm born (EPB) infants are at risk of a range of complications, among them a patent ductus arteriosus (PDA). If a conservative approach does not reduce the cardiopulmonary compromise imposed by ... -
Outdoor air pollution and hormone-assessed pubertal development in children: Results from the GINIplus and LISA birth cohorts
(Journal article; Peer reviewed, 2021)Background Air pollution is hypothesized to affect pubertal development. However, the few studies on this topic yielded overall mixed results. These studies did not consider important pollutants like ozone, and none of ... -
Overcoming addition of phosphoethanolamine to lipid A mediated colistin resistance in Acinetobacter baumannii clinical isolates with colistin–sulbactam combination therapy
(Journal article; Peer reviewed, 2022)Overcoming colistin-resistant Acinetobacter baumannii (CoR-AB) has become a major concern due to the lack of effective antibiotics. This study aimed to explore the prevalence of CoR-AB clinical isolates in Thailand, their ... -
Overweight and obesity in children: a study of weight-related anthropometric variables in childhood
(Doctoral thesis, 2015-11-13) -
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
(Journal article; Peer reviewed, 2020)Oxidation resistance gene 1 (OXR1) protects cells against oxidative stress. We find that male mice with brain-specific isoform A knockout (Oxr1A−/−) develop fatty liver. RNA sequencing of male Oxr1A−/− liver indicates ... -
Oxygen concentration in inhaled gas and nitric oxide concentration in exhaled gas. Is nitric oxide concentration in exhaled gas a useful marker for exposure to hyperoxia?
(Doctoral thesis, 2014-04-10)Background: Exposure to partial pressures of oxygen (PO2) higher than 50 kPa may result in toxic effects on the lungs with reduced vital capacity, maximal expiratory flow rates and diffusion capacity. The risk of developing ... -
p53 protein biosignatures in acute myeloid leukemia
(Doctoral thesis, 2006-03-10)p53 is a tumor suppressor protein often regarded as the guardian of the genome. It is a highly connected protein involved in many signaling processes in the cell. The inactivation of p53 through genetic mutations in TP53 ... -
p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy
(Journal article; Peer reviewed, 2021)p53 protein isoform expression has been found to correlate with prognosis and chemotherapy response in acute myeloid leukemia (AML). We aimed to investigate how p53 protein isoforms are modulated during epigenetic ... -
Pain and pain tolerance in whiplash-associated disorders:A population-based study
(Peer reviewed; Journal article, 2015)Background: Pain is a cardinal symptom in individuals with whiplash-associated disorders (WAD). We aimed to compare pain characteristics between individuals with WAD and individuals reporting chronic pain from other causes, ... -
Paradoxical sinus deceleration during dobutamine stress echocardiography: case series and review of the literature
(Journal article; Peer reviewed, 2022)Background: Dobutamine stress echocardiography is an established diagnostic modality for assessing myocardial ischaemia in patients with known or suspected coronary artery disease. Dobutamine infusion causes dose-dependent ...