Browsing Department of Clinical Science by Title
Now showing items 2167-2186 of 2308
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Thrombosis and thrombocytopenia after HPV vaccination
(Journal article; Peer reviewed, 2021)Background Vaccine-induced immune thrombotic thrombocytopenia (VITT) has so far only been reported after adenovirus vector severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines. Objective We report ... -
Thrombus characteristics evaluated by acute optical coherence tomography in ST elevation myocardial Infarction
(Journal article; Peer reviewed, 2022)Aims ST elevation myocardial infarction (STEMI) is caused by an occlusive thrombosis of a coronary artery. We wanted to assess if the thrombus can be characterized according to erythrocyte content and age using intravascular ... -
Tick-borne infections in Sogn og Fjordane, western Norway. Seroprevalence, risk factors and subjective health complaints in blood donors
(Doctoral thesis, 2017-09-15)Background: The tick Ixodes ricinus is involved in the transmission of a large variety of pathogens of medical and veterinary importance in Norway. The most prevalent human tickborne disease in the country is Lyme borreliosis, ... -
Tidal breathing parameters in extremely premature infants. Feasibility and clinical utility of electromagnetic inductance plethysmography
(Doctoral thesis, 2018-09-06)Background: Extremely preterm (EP) birth is associated with adverse lung growth, due to disturbance of programmed and fine-tuned sequences of normal intrauterine development, as well as the trauma inflicted by life-saving ... -
Tidal Expiratory Flow Limitation. A new method for evaluating pulmonary function in elderly and patients with Chronic Obstructive Pulmonary Disease
(Doctoral thesis, 2018-01-18)Background: Lung function declines with old age and is further accelerated by exposure to noxious particles. As our society ages, expected lifespan increases, and prevalence of chronic obstructive pulmonary disease (COPD) ... -
Tidal volumes and pressures delivered by the NeoPuff T-piece resuscitator during resuscitation of term newborns
(Journal article; Peer reviewed, 2022)Aim: T-piece resuscitators are commonly used for respiratory support during newborn resuscitation. This study aimed to describe delivered pressures and tidal volumes when resuscitating term newborns immediately after birth, ... -
Tidal volumes and pressures delivered by the NeoPuff T-piece resuscitator during resuscitation of term newborns
(Journal article; Peer reviewed, 2022)Aim: T-piece resuscitators are commonly used for respiratory support during newborn resuscitation. This study aimed to describe delivered pressures and tidal volumes when resuscitating term newborns immediately after birth, ... -
Tigecycline attenuates polymorphonuclear leukocyte (PMN) receptors but not functions
(Peer reviewed; Journal article, 2011)Tigecycline achieves high intracellular concentrations in polymorphonuclear leukocytes (PMNs). To evaluate the effects of tigecycline on human PMNs, PMNs were incubated with tigecycline dilutions (0.1 to 100 mg L–¹). ... -
Time-Resolved Concentrations of Serum Amino Acids, One-carbon Metabolites, and B-vitamin Biomarkers during the Postprandial and Fasting State: The Postprandial Metabolism in Healthy Young Adults (PoMet) study
(Journal article; Peer reviewed, 2023)Metabolomics has been utilised in epidemiological studies to investigate biomarkers of nutritional status and metabolism in relation to non-communicable diseases. However, little is known about the effect of prandial status ... -
Timing of menarche in Norwegian girls: Associations with body mass index, waist circumference and skinfold thickness
(Peer reviewed; Journal article, 2017-06-06)Background: Research studies show conflicting results regarding the association between menarche and body weight. The purpose of the present study was to investigate if anthropometric indicators of body composition, body ... -
Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer
(Peer reviewed; Journal article, 2016-09-13)Hypoxia is frequent in solid tumors and linked to aggressive phenotypes and therapy resistance. We explored expression patterns of the proposed hypoxia marker HIF-1α in endometrial cancer (EC) and investigate whether ... -
Tissue characterisation by ultrasound strain imaging. Methodological aspects and gastroenterological applications
(Doctoral thesis, 2012-10-11)Real-Time Elastography (RTE) is a new imaging modality that monitors tissue strain during applied stress. The aim of this thesis was to validate if RTE was a reliable modality to reflect pathologically induced differences ... -
Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
(Journal article; Peer reviewed, 2022)Diagnostic assays currently used to monitor the efficacy of COVID-19 vaccines measure levels of antibodies to the receptor-binding domain of ancestral SARS-CoV-2 (RBDwt). However, the predictive value for protection against ... -
Titrating complex mass cytometry panels
(Peer reviewed; Journal article, 2019-07-13)We describe here a simple and efficient antibody titration approach for cell‐surface markers and intracellular cell signaling targets for mass cytometry. The iterative approach builds upon a well‐characterized backbone ... -
TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies
(Journal article; Peer reviewed, 2020)Inflammation and oxidative stress at the maternal‐fetal interface characterize the placental dysfunction that underlies the pregnancy disorder preeclampsia. Specialized fetal trophoblasts directly interact with leukocytes ... -
TNF-α is associated with loss of lean body mass only in already cachectic COPD patients
(Peer reviewed; Journal article, 2012-06-18) -
Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia
(Journal article; Peer reviewed, 2022-01-23)Toll-like receptor 4 (TLR4) is a pattern-recognizing receptor that can bind exogenous and endogenous ligands. It is expressed by acute myeloid leukemia (AML) cells, several bone marrow stromal cells, and nonleukemic cells ... -
Toluene diisocyanate (TDI)-induced asthma: Inflammatory and immunological responses to TDI, ovalbumin (OVA) and ovalbumin peptide OVA 323-339 in mouse models
(Doctoral thesis, 2012-06-07)Among three major diisocyanates: TDI, methylenediphenyl diisocyanate (MDI) and hexamethylene diisocyanate (HDI), TDI has been regarded as the leading cause of diisocyanate-induced asthma. The principal feature of TDI-induced ... -
Total Bilirubin Yields Prognostic Information Following a Myocardial Infarction in the Elderly
(Journal article; Peer reviewed, 2023)Total bilirubin consists of an unconjugated form, solubilized by its binding to albumin, and a conjugated form representing a minor part of the circulating bilirubin. As total bilirubin in physiological concentrations is ... -
Total circulating cell-free DNA as a prognostic biomarker in metastatic colorectal cancer before first-line oxaliplatin-based chemotherapy
(Peer reviewed; Journal article, 2019-05-02)Background: Metastatic colorectal cancer (mCRC) is a heterogeneous disease where prognosis is dependent both on tumor biology and host factors. Total circulating cell-free DNA (cfDNA) has shown to harbor prognostic information ...