Browsing Department of Clinical Science by Title
Now showing items 658-677 of 2310
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The effects of smoking cessation intervention in patients with coronary heart disease : a randomised, controlled trial
(Doctoral thesis, 2007-02-09)Background: Smoking cessation is the most important action to reduce mortality after a coronary event. Largely, it has previously been unknown whether a smoking cessation program applicable in an ordinary clinical setting ... -
Effects of SNP variants in the 17β-HSD2 and 17β-HSD7 genes and 17β-HSD7 copy number on gene transcript and estradiol levels in breast cancer tissue
(Peer reviewed; Journal article, 2014-02-18)Breast cancers reveal elevated E2 levels compared to plasma and normal breast tissue. Previously, we reported intra-tumour E2 to be negatively correlated to transcription levels of 17β-HSD2 but positively correlated to ... -
Effects of the Autophagy-Inhibiting Agent Chloroquine on Acute Myeloid Leukemia Cells; Characterization of Patient Heterogeneity
(Journal article; Peer reviewed, 2021)Autophagy is a highly conserved cellular degradation process that prevents cell damage and promotes cell survival, and clinical efforts have exploited autophagy inhibition as a therapeutic strategy in cancer. Chloroquine ... -
Effekt av havregrynsgrøt på tykktarmens bakterieflora En eksplorativ studie av fekal beta-galaktosidase galaktosidaseog ureaseaktivitet i tykktarmen hos friske forsøkspersoner
(Master thesis, 2009-05-07)Irritabel tarm (IBS) er en kronisk lidelse som rammer ca. 15 prosent av befolkningen, og kjennetegnes ved magesmerter, oppblåsthet/gassplager og avføringsforstyrrelser. Det er mye som tyder på at bakteriefloraen til pasienter ... -
Efficacy and safety of 4 weeks' treatment with combined fluticasone furoate/vilanterol in a single inhaler given once daily in COPD: a placebo-controlled randomised trial
(Peer reviewed; Journal article, 2012-01-19)Background. Fluticasone furoate/vilanterol (FF/VI) is a novel once-daily (OD) inhaled corticosteroid/long-acting β2 agonist combination in development for chronic obstructive pulmonary disease (COPD) and asthma. Trial ... -
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID‑19 (Bari‑SolidAct): a randomised, double‑blind, placebo‑controlled phase 3 trial
(Journal article; Peer reviewed, 2023)Background Baricitinib has shown efficacy in hospitalized patients with COVID-19, but no placebo-controlled trials have focused specifically on severe/critical COVID, including vaccinated participants. Methods Bari-SolidAct ... -
Efficacy of adrenal venous sampling is increased by point of care cortisol analysis
(Peer reviewed; Journal article, 2013)Primary aldosteronism (PA) is a common cause of secondary hypertension and is caused by unilateral or bilateral adrenal disease. Treatment options depend on whether the disease is lateralized or not, which is preferably ... -
Eksamensformer i de norske medisinstudiene
(Journal article; Peer reviewed, 2022)BAKGRUNN Det finnes ingen samlet oversikt over hvilke eksamensformer som er i bruk i de norske medisinstudiene. I denne studien har vi kartlagt hvilke eksamensformer som er i bruk, og analysert studieledelsenes begrunnelser ... -
Ekspressiv skriving som egenterapeutisk verktøy ett år etter brystkreftdiagnosen - resultater fra en beskrivende pilotstudie
(Peer reviewed; Journal article, 2014)The article presents findings from a pilot study on expressive writing, a therapeutic method undescribed in a Norwegian scientific context. Objective: 1. Gain qualitative data on breast cancer women’s experiences with ... -
Elderly patients’ (≥65 years) experiences associated with discharge; Development, validity and reliability of the Discharge Care Experiences Survey
(Peer reviewed; Journal article, 2018-11-07)Background: A review of the literature reveals a lack of validated instruments that particularly measure quality in the hospital discharge process. This study aims to develop and validate a survey instrument feasible for ... -
Electrolyte imbalances in an unselected population in an emergency department: A retrospective cohort study
(Peer reviewed; Journal article, 2019-04-25)Background: Although electrolyte imbalances (EIs) are common in the emergency department (ED), few studies have examined the occurrence of such conditions in an unselected population. Objectives: To investigate the frequency ... -
Electromagnetic inductance plethysmography is well suited to measure tidal breathing in infants
(Journal article; Peer reviewed, 2016)Reliable, accurate and noninvasive methods for measuring lung function in infants are desirable. Electromagnetic inductance plethysmography has been used to perform infant spirometry and VoluSense Pediatrics (VSP) (VoluSense, ... -
Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
(Peer reviewed; Journal article, 2018)Ankyrin-3 (ANK3) is one of the few genes that have been consistently identified as associated with bipolar disorder by multiple genome-wide association studies. However, the exact molecular basis of the association remains ... -
Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement
(Journal article; Peer reviewed, 2021)Background A high proportion of COVID‐19 patients have cardiac involvement, even those without known cardiac disease. Downregulation of angiotensin converting enzyme 2 (ACE2), a receptor for SARS‐CoV‐2 and the renin‐angiotensin ... -
Elevated plasma cystathionine is associated with increased risk of mortality among patients with suspected or established coronary heart disease
(Journal article; Peer reviewed, 2019)Background Elevated circulating cystathionine levels are related to atherosclerotic cardiovascular disease, a leading cause of death globally. Objective We investigated whether plasma cystathionine was associated with ... -
ELISA-basert deteksjon av biomarkørar i serumprøver ved Giardia-indusert kronisk utmattingssyndrom og funksjonelle gastrointestinale lidingar - Nivå av B-cell activating factor og antistoff mot cytolethal distending toxin B og flagellin hjå personar med langvarige plager etter Giardia-utbrotet i Bergen
(Master thesis, 2017-06-08)Bakgrunn: Parasitten Giardia lamblia forureina drikkevasskjelda Svartediket i Bergen hausten 2004, og var årsaka til eit stort utbrot av giardiasis i menneske. Denne gastrointestinale infeksjonen blei for mange starten på ... -
Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307
(Peer reviewed; Journal article, 2019)Objectives: Recent reports indicate the emergence of a new carbapenemase-producing Klebsiella pneumoniae clone, ST307. We sought to better understand the global epidemiology and evolution of this clone and evaluate its ... -
Emergence of a Streptococcus dysgalactiae subspecies equisimilis stG62647-lineage associated with severe clinical manifestations
(Peer reviewed; Journal article, 2017-08-08)Increasing incidence rates of invasive Streptococcus dysgalactiae subspecies equisimilis (SDSE) infections have been reported worldwide, but the evolutionary mechanisms underlying this development remain elusive. Through ... -
The emerging role of cd24 in cancer theranostics—a novel target for fluorescence image-guided surgery in ovarian cancer and beyond
(Journal article; Peer reviewed, 2020)Complete cytoreductive surgery is the cornerstone of the treatment of epithelial ovarian cancer (EOC). The application of fluorescence image-guided surgery (FIGS) allows for the increased intraoperative visualization and ... -
emm gene diversity, superantigen gene profiles and presence of SlaA among clinical isolates of group A, C and G streptococci from western Norway
(Peer reviewed; Journal article, 2010-11-20)In order to investigate molecular characteristics of beta-hemolytic streptococcal isolates from western Norway, we analysed the entire emm gene sequences, obtained superantigen gene profiles and determined the prevalence ...