Browsing Department of Clinical Medicine by Title
Now showing items 180-199 of 2082
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Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjogren's syndrome in salivary glands of non-obese diabetic mice
(Peer reviewed; Journal article, 2009-02-18)Introduction The lymphotoxin-beta receptor (LTβR) pathway is important in the development and maintenance of lymphoid structures. Blocking this pathway has proven beneficial in murine models of autoimmune diseases such as ... -
Blood Pressure Treatment in Kidney Transplant Recipients—Can We Improve?
(Journal article; Peer reviewed, 2021)Background. Hypertension in kidney transplant (KTx) recipients is common, affecting both patient and graft survival. Annual data from the Norwegian Renal Registry reveal that <50% of adult (>18 y) KTx recipients reach ... -
Blue-blocking glasses as additive treatment for mania: A randomized placebo-controlled trial
(Peer reviewed; Journal article, 2016-05)Objectives: The discovery of the blue lightsensitive retinal photoreceptor responsible for signaling daytime to the brain suggested that light to the circadian system could be inhibited by using blue-blocking orange tinted ... -
Blue-blocking glasses as adjunctive treatment for bipolar mania - and exploration of motor activity patterns in serious mental disorders
(Doctoral thesis, 2020-10-23)Background: There is a need for more effective treatments of bipolar mania. Promising reports of the effects of dark therapy on bipolar disorder symptoms and the discovery of a mainly blue-light sensitive daylight-signaling ... -
Bone cement product and failure in total knee arthroplasty: A follow-up study of 26,147 knee replacements between 1997 and 2013 in Norway
(Peer reviewed; Journal article, 2017)Background and purpose — The bone cement market for total knee arthroplasty (TKA) in Norway has been dominated by a few products and distributors. Palacos with gentamicin had a market share exceeding 90% before 2005, but ... -
Bowel function and quality of life after superior mesenteric nerve plexus transection in right colectomy with D3 extended mesenterectomy
(Peer reviewed; Journal article, 2016)Background: The aim of this study was to ascertain the impact of injury to the superior mesenteric nerve plexus caused by right colectomy with D3 extended mesenterectomy as performed in the prospective multicenter trial: ... -
Bowel Perfusion Measured with Dynamic Contrast-enhanced Ultrasound Predicts Treatment Outcome in Patients with Crohn’s Disease
(Peer reviewed; Journal article, 2014-09-02)Background: To improve management of patients with Crohn's disease (CD), objective measurements of the degree of local inflammation in the gastrointestinal wall are needed. Increased microvessel density and perfusion are ... -
Brain amyloid and vascular risk are related to distinct white matter hyperintensity patterns
(Journal article; Peer reviewed, 2020)White matter hyperintensities (WMHs) are associated with vascular risk and Alzheimer’s disease. In this study, we examined relations between WMH load and distribution, amyloid pathology and vascular risk in 339 controls ... -
Brain atrophy and clinical characteristics predicting SDMT performance in multiple sclerosis: A 10-year follow-up study
(Journal article; Peer reviewed, 2021)Objectives To identify Magnetic Resonance Imaging (MRI), clinical and demographic biomarkers predictive of worsening information processing speed (IPS) as measured by Symbol Digit Modalities Test (SDMT). Methods Demographic, ... -
Brain atrophy and employment in multiple sclerosis patients: a 10-year follow-up study
(Journal article; Peer reviewed, 2020)Background: Multiple sclerosis is often associated with unemployment. The contribution of grey matter atrophy to unemployment is unclear. Objectives: To identify magnetic resonance imaging biomarkers of grey matter and ... -
Brain changes induced by electroconvulsive therapy are broadly distributed
(Peer reviewed; Journal article, 2020-03-01)Background Electroconvulsive therapy (ECT) is associated with volumetric enlargements of corticolimbic brain regions. However, the pattern of whole-brain structural alterations following ECT remains unresolved. Here, we ... -
Brain lateralization, attention and cognitive control in presistent Attention-Deficit/Hyperactivity Disorder
(Doctoral thesis, 2011-12-09)Objective: Divergent brain lateralization and dysfunctional attention and cognitive control may be part of the pathophysiology of ADHD, with the corpus callosum (CC) and the anterior cortex cinguli (ACC) as important ... -
“Brain MR spectroscopy in autism spectrum disorder—the GABA excitatory/inhibitory imbalance theory revisited”
(Peer reviewed; Journal article, 2015-06-22)Magnetic resonance spectroscopy (MRS) from voxels placed in the left anterior cingulate cortex (ACC) was measured from 14 boys with Autism Spectrum Disorder (ASD) and 24 gender and age-matched typically developing (TD) ... -
Brain MRI changes in Parkinson’s disease A cross sectional study
(Doctoral thesis, 2007-11-09)Background: Cognitive impairment is common even in newly diagnosed Parkinson’s disease (PD), and characteristically involves executive and visuospatial functions with deficits also in the memory domain. There is an increased ... -
Breast cancer of the young: Exploring age-related breast cancer biology
(Doctoral thesis, 2023-11-30)Brystkreft er en sykdom som i en økende grad rammer kvinner i Norge og den vestlige verden. Brystkreft blant yngre kvinner er også økende, og dessuten assosiert med mer aggressiv tumor type og verre klinisk utfall sammenlignet ... -
Breast cancer stromal elastosis is associated with mammography screening detection, low Ki67 expression and favourable prognosis in a population-based study
(Peer reviewed; Journal article, 2014-12-19)Background: Mammography screen-detected breast cancers have a better prognosis than predicted from established prognostic markers. A search for additional features that are characteristic for these tumours and their prognosis ... -
Breast-Specific Molecular Clocks Comprised of ELF5 Expression and Promoter Methylation Identify Individuals Susceptible to Cancer Initiation
(Journal article; Peer reviewed, 2021)A robust breast cancer prevention strategy requires risk assessment biomarkers for early detection. We show that expression of ELF5, a transcription factor critical for normal mammary development, is downregulated in mammary ... -
Bridging the Gap for Children With Compound Health Challenges: An Intervention Protocol
(Journal article; Peer reviewed, 2021)Background: During the last decades, there is a major shift in the panorama of diseases in children and adolescents. More children are referred to the specialized health care services due to less specific symptoms and more ... -
Brief international cognitive assessment for MS (BICAMS) and global brain volumes in early stages of MS – A longitudinal correlation study
(Journal article; Peer reviewed, 2023)Background: Cognitive impairment is common in patients with multiple sclerosis, even in the early stages of the disease. The Brief International Cognitive Assessment for multiple sclerosis (BICAMS) is a short screening ... -
Buegangsdehiscens
(Journal article; Peer reviewed, 2022)Buegangsdehiscens er en tilstand med plagsomme øresymptomer og svimmelhet forårsaket av en defekt i benet mellom det indre øret og midtre skallegrop. Sykdommen er ufarlig, og for mange pasienter er det tilstrekkelig med ...